Sentences with phrase «study human disorders»

While Pollard's research focuses on understanding the microbiome through bioinformatics and modeling, other projects study human disorders such as diabetes and asthma, the impact of the ocean and soil on climate change, and the influence of plants, animals, and water on food production.

Not exact matches

Twenge and Campbell are drawing here on research from the so - called positive psychology movement, which recently has attempted to shift the focus of psychological research away from disease and disorder to a study of the character strengths that make for happiness and human flourishing.

Moreover, it is widely believed that personal and social disorders can be cured and human potentialities can be released through the careful study of man and society.

A 2012 study found that consuming maltodextrin increased bacterial adhesion to human intestinal epithelial cells and enhanced E. coli adhesion, which is associated with autoimmune disorders and dybiosis in your gut.

Studies show that dioxins collect in the fatty tissues of animals and humans, and even low levels of exposure can lead to cancer, endometriosis, birth defects, and reproductive disorders.

Some studies have also linked the microbiome to human mood and behavior as well as gut health, human development, and metabolic disorders.

Of the thousands of ancestral variants reintroduced into modern humans, only 41 have been linked in genetic studies to diseases, such as skin conditions and neurological and psychiatric disorders, he said.

'» (Translate is planning human trials with repeated doses of its own mRNA drug for both cystic fibrosis and a rare metabolic disorder called ornithine transcarbamylase deficiency in 2018, but it has not yet published animal studies with repeat dosing.)

Professor Jianfeng Feng commented that new technology has made it possible to conduct this trail - blazing study: «human intelligence is a widely and hotly debated topic and only recently have advanced brain imaging techniques, such as those used in our current study, given us the opportunity to gain sufficient insights to resolve this and inform developments in artificial intelligence, as well as help establish the basis for understanding and diagnosis of debilitating human mental disorders such as schizophrenia and depression.»

In humans, neural oscillations are often studied in relation to epilepsy and various sleeping disorders though questions remain about their precise function.

This study highlights the shared genetic etiology of many canine and human genetic disorders, and provides new tools to investigate PRA mechanisms while the beloved dogs benefit from genetic testing.

A recent study published in Annals of Neurology reports that healthy human tissue grafted to the brains of patients with Huntington's disease in the hopes of treating the neurological disorder also developed signs of the illness, several years after the graft.

By studying these disorders, scientists can learn a lot about human social cognition.

«The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders,» says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study.

Now, in this week's issue of the Proceedings of the National Academy of Sciences, Thomas Albright and Ricardo Gil - da - Costa of the Salk Institute for Biological Studies describe a model system that completes the bridge between cellular and human studies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disStudies describe a model system that completes the bridge between cellular and human studies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disstudies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disorders.

If dozens of human and animal studies published over the past six years are borne out by large clinical trials, nicotine — freed at last of its noxious host, tobacco, and delivered instead by chewing gum or transdermal patch — may prove to be a weirdly, improbably effective drug for relieving or preventing a variety of neurological disorders, including Parkinson's disease, mild cognitive impairment (MCI), Tourette's and schizophrenia.

Treatment implications were examined in a series of human studies that demonstrated similar reductions in the microbiome in participants suffering from both major depression and bipolar disorder.

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.

In response to the recent revelations, an international group of researchers has launched a project called the Human Dark Proteome Initiative to study how disordered proteins cause disease.

«The imaging technique could shed light on the immune dysfunction that underpins a broad range of neuroinflammatory diseases, such as Alzheimer's disease, depression, post-traumatic stress disorder and addiction,» said Christine Sandiego, PhD, lead author of the study and a researcher from the department of psychiatry at the Yale School of Medicine in New Haven, Conn. «This is the first human study that accurately measures this immune response in the brain.

«Horse sickness shares signs of human brain disorders, study finds.»

Among those is canine compulsive disorder (CCD), the counterpart to human obsessive compulsive disorder (OCD),» says the study's first and corresponding author Nicholas Dodman, BVMS, DACVA, DACVB, professor in clinical sciences and section head and program director of animal behavior at Cummings School of Veterinary Medicine at Tufts University.

«Finches offer researchers a new tool with which to study Huntington's disease: Like humans, songbirds learn their vocalizations, suggesting they could be useful as models for certain disorders.»

Now, a new study in mice shows how a gene, called FOXP2, implicated in a language disorder may have changed between humans and chimps to make learning to speak possible — or at least a little easier.

By now, European astronauts had hoped to be established in their space laboratory called Columbus, where they would be melting and solidifying conductive metals, studying microgravity effects on single - celled organisms, investigating human balance disorders, and carrying out dozens of other experiments.

«The malfunction in this protein has not been previously linked to clinical disorders of the human immune system,» said Ivona Aksentijevich, M.D., staff scientist in NHGRI's Medical Genetics Branch and study co-author.

In a study spanning molecular genetics, stem cells and the sciences of both brain and behavior, researchers at University of California San Diego, with colleagues at the Salk Institute of Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights into the underlying neurobiology of the human social brain.

The study, led by Dr. Maximilian Muenke of the National Human Genome Research Institute in Bethesda, Maryland, brings scientists closer to understanding how ADGRL3 contributes to risk by providing functional evidence that implicates a transcription factor in the pathology of the disorder.

Already studies on WS have spurred investigators to think about new ways of looking at common disorders of human aging.

The letter further contends that recent chimp studies for the first time have identified «unique features of the human brain and have documented the unusual vulnerability of humans to a variety of disorders, including Alzheimer's disease, infectious diseases, cancer, and heart disease.»

Genome - wide association studies of eating disorders in humans have been limited in their power to detect significant associations between genotype and disease or disease traits such as binge eating.

Now, one researcher is studying them for another reason: Their behavior may provide clues to the genetic basis of some human psychiatric disorders.

Most modern studies of bipolar disorder have concentrated on the brain's cortex, the largest part of the brain in humans, associated with higher - level thought and action.

The study helps explain a distinctly human mechanism of cognition, said the lead researchers at Brown University, and could be applied to studying and treating reward - seeking or punishment - avoidance conditions such as addiction or obsessive - compulsive disorder.

The scientists say their study, published in Frontiers of Neuroscience, opens a pathway to studying bat brains in order to understand certain human language disorders and potentially even improving computer speech recognition.

The genetic causes of bipolar disorder are highly complex and likely involve many different genes, said Carrie Bearden, a senior author of the study and an associate professor of psychiatry and psychology at the UCLA Semel Institute for Neuroscience and Human Behavior.

Dr. Zhu said he believes the study provides the scientific community with an important animal model to further investigate ARID1B's role in human brain disorders and will be a useful tool for therapeutic testing of potential treatments for autism, intellectual disability, and Coffin - Siris syndrome.

«Unfortunately, there are no preventive therapies for any common disorder of the human nervous system — Alzheimer's, Parkinson's, schizophrenia, epilepsy — with the exception of blood pressure - lowering drugs to reduce the likelihood of stroke,» said study author James O. McNamara, M.D., professor of neurobiology at Duke Medicine.

«We can't guess the biology of human brains and neurodevelopmental disorders just by studying mouse brains.»

In the new study, the researchers discovered that during the second trimester of human brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects in which have previously been implicated in autism and several other psychiatric disorders.

«This program reaches an extremely vulnerable population at an extremely vulnerable time with the best treatment available for opioid use disorder,» said study co-author Dr. Josiah «Jody» Rich, professor of medicine and epidemiology at Brown University and director of the Center for Prisoner Health and Human Rights at The Miriam Hospital in Providence.

The feat means that scientists now can relatively easily study DRG sensory neurons derived from many different people, to better understand the diversity of human sensory responses and sensory disorders and advance a «personalized medicine» approach.

The study, funded by the NIH / NIAAA, also demonstrates the great potential value of preclinical studies for understanding human disorders.

«Future studies on how PAF / PAFR signaling controls UCP1 levels through beta3 - AR production in the BAT of animals and humans may reveal new therapeutic targets to treat metabolic disorders associated with obesity,» said Junko Sugatani, Ph.D., a researcher involved in the work from the Department of Pharmaco - Biochemistry at the School of Pharmaceutical Sciences at the University of Shizuoka in Shizuoka, Japan.

Another big reason for studying real vampires, as if scientists need another, is the possibility of finding new insights into human metabolic disorders.

«Massive single - cell survey of kidney cell types reveals new paths to disease: Study of over 57,000 cells from mouse kidneys help identify human renal disorders.»

«Genetically altered mice bear some hallmarks of human bipolar behavior: Study shows the behavior responds to lithium treatment, just as used in people with the disorder.»

The researchers also suggest their study may shed light on how fear disorders such as post-traumatic stress disorder (PTSD) develop in humans, which research shows can be influenced by social environment; PTSD symptoms can be acquired from friends or family who have suffered trauma, for example.

1990s, your class may have studied the molecular basis for human genetic disorders, like cystic fibrosis.

The study, published in Proceedings of the National Academy of Sciences (PNAS), utilized human induced pluripotent stem cells (hiPS cells) to map lithium's response pathway, enabling the larger pathogenesis of bipolar disorder to be identified.