«The influenza field is largely fixated on studying pandemic or potential pandemic viruses, but those viruses only infect a few dozen people every year whereas seasonal flu infects millions — and yet we don't
study human influenzas closely enough.»
Not exact matches
«You render the most pathogenic
influenza virus known to
humans nontransmissible — that's fascinating,» says bioengineer Ram Sasisekharan of the Massachusetts Institute of Technology, who was not part of the
study.
Weiner, Elliott and colleagues
studied the DNA sequences for two
human monoclonal antibodies — one able to broadly target
influenza A viruses and one able to broadly target
influenza B viruses — with collaborators at Inovio and MedImmune.
The
study, led by Nancy J. Cox of the Centers of Disease Control and Prevention describes a molecular analysis of the novel
influenza A (H1N1) virus infecting
humans in several parts of the world.
If further
studies in
humans prove successful, this research could have broad implications for the prevention of
influenza and, by extension, as an approach for other infectious diseases as well.
A new
study has found that a novel avian - origin H7N9
influenza A virus, which has recently emerged in
humans, attaches moderately or abundantly to the epithelium of both the upper and lower respiratory tracts.
It's been well researched, by
studies, by world organizations, by the Centre for Disease Control in Atlanta, other organizations that have all unanimously come to the conclusion that consumption of pork is not a risk factor for transmission of
influenza virus from swine to
human.
To date, most
studies have focused on the
influenza A virus lineages because they are the more commonly circulating lineages in
humans which have also caused occasional pandemics.
«The whole purpose is to
study the responses of
human and animal bodies to infection from
influenza, Ebola, SARS and MERS, and to understand how they occur,» Kawaoka explains.
A new
study, led by Assistant Professor Vijay Dhanasekaran and Associate Professor Gavin Smith from Duke - NUS Graduate Medical School (Duke - NUS), has presented the largest comparative analysis of
human influenza B viruses undertaken to date.
The
study made many headlines, in part because of the fear that the H5N1 avian
influenza virus, which so far transmits poorly between
humans, could undergo a similarly fateful transformation.
The loss was bad for the vaccine: In a series of experiments Hensley and his colleagues showed antibodies from
humans and ferrets (a good animal model for
influenza A
studies) that had been exposed to the egg - grown vaccine did not effectively kill the circulating sugar - adorned viruses.
Human challenge
studies with
influenza provide a glimpse of the new landscape.
As a controversial
study of the H5N1 avian
influenza virus published online today in Science shows, researchers are keenly interested in how mutations in the virus» genes might enable it to become transmissible in
humans.
Avian
influenza virus H7N9, which killed several dozen people in China earlier this year, has not yet acquired the changes needed to infect
humans easily, according to a new
study by scientists at The Scripps Research Institute (TSRI).
The mouse is described in a
study, «In vivo evasion of MxA by avian
influenza viruses requires
human signature in the viral nucleoprotein,» that will be published April 10 in The Journal of Experimental Medicine.
To capture the early spatial patterns of a newly emergent virus in swine populations prior to extensive geographical mixing, this
study focused on an H1
influenza virus that was introduced twice from
humans into swine around 2003.
Deep Sequencing of
Influenza A Virus from a
Human Challenge
Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification.
LA JOLLA, CA — December 5, 2013 — Avian
influenza virus H7N9, which killed several dozen people in China earlier this year, has not yet acquired the changes needed to infect
humans easily, according to a new
study by scientists at The Scripps Research Institute (TSRI).
Specifically, we will test samples from aged and, as a control, younger
human subject before and after vaccination with the trivalent inactivated
influenza vaccine (TIV) in an exploratory / confirmatory
study design to assess age - related responsiveness to the vaccine.
The
study relates to a particular type of vaccine (killed) against a particular virus,
influenza, though the findings might hold true for other killed vaccines and for those vaccines consisting only of proteins produced by GM in bacteria, yeast or insect cells, against diseases such as hepatitis B (HBV) and
human papilloma virus (HPV, the causative agent of cervical cancer).
A recent
study led by BSI member Professor Andrew Sewell from Cardiff University and published in the Journal of Clinical Investigation showed that a synthetic «mirror image» version of a protein belonging to the
influenza A virus generated strong immune responses in
human cells and mice, with the mice also being protected when exposed to a strain of
influenza A.
The
study, «Preferential Recognition of Avian - Like Receptors in
Human Influenza A H7N9 Viruses,» received support from the National Institutes for Health (R56 AI099275), the Skaggs Institute for Chemical Biology, the Scripps Microarray Core Facility, the Centers for Disease Control and the Netherlands Organization for Scientific Research.
MIT
study identifies
influenza viruses circulating in pigs and birds that could pose a risk to
humans.