Sentences with phrase «study investigators reported»

In 2011, the HPTN 052 study investigators reported a breakthrough: Starting HIV treatment early, when the immune system is relatively healthy, reduced the risk of sexually transmitting the virus to an uninfected partner by 96 percent over 18 months.

Not exact matches

The study was published in two volumes: The Purpose of the Church and Its Ministry, in which Niebuhr developed a theological account of ministry on the basis of a theological analysis of what the church is, and a report and interpretation of research prepared by the three investigators, The Advancement of Theological Education.10

«This is the first study to report an association between handheld screen time and increased risk of expressive language delay,» noted pediatrician Dr. Catherine Birken, MD, MSc, FRCPC, the study's principal investigator.

In these studies, investigators made an attempt to blind outcome assessors, however, because women knew their group allocation, and all data were self - reported, the group allocation could have been revealed during data collection.

Other investigators have reported a significant increase in adverse perinatal outcomes related to planned home births, especially where skilled birth attendants are not universally integrated into regional health systems, or in population - based studies that include at - risk pregnancies [20 — 22].

In this Focus on Education report, WBFO's Eileen Buckley talks to the principal investigator of the study.

People who give up activities and outlets they enjoy such as exercise, music, or art while in graduate school or medical training are more likely to report emotional distress, according to Liselotte Dyrbye, an internist and investigator at the Mayo Clinic in Rochester, Minnesota, who has studied suicidal thoughts among U.S. medical students.

With this kind of review process, if 20 studies of the effectiveness of a truly ineffective drug are conducted, and one of them shows a significant effect with a p - value of 0.05 because of chance alone, investigators for the other 19 studies not showing any effect would presumably not be inhibited from writing up and submitting reports of these for publication out of fear that they'll be denied publication because of their nonsignificant results.

In a study published in Cell Reports, researchers lead by Cédric Blanpain, MD / PhD, WELBIO investigator and Professor at the Université libre de Bruxelles, Belgium, identified a novel lineage - restricted stem cell in the mammary gland.

In a study published in Nature Communications, the investigators report that hyperglycemic mice (or mice with type 2 diabetes) have a 24-fold higher accumulation of succinate, an intermediate metabolite, in the metabolic pathways of their bone marrow stromal cells.

A recent study by investigators from LIJ Medical Center demonstrated that using magnetic resonance imaging (MRI) in men with an elevated prostate specific antigen (PSA) resulted in a prostate cancer detection rate that was twice as high as data reported in the March 1999 Prostate journal that analyzed men undergoing the standard 12 - core biopsy with an elevated PSA.

After six months on the trial, 95 percent of participants reported no problems taking the drug, and while several discontinued treatment for varying periods of time during the study period, the investigators estimate that 90 percent would have tolerated the treatment if they had continued the full two years.

Study subjects who received a 3 - milligram (3 - mg) dose of liraglutide lost an average of 8 percent of their body weight (18.7 pounds), compared with just 2.6 percent (6.2 pounds) for subjects receiving a placebo, or «dummy» drug, the investigators reported.

Study investigators have been following the children since birth, and the current research report evaluates the group through 7 years of age.

The investigators found that the proportion of study participants living with HIV who reported taking ART climbed from zero in 2003 to 69 percent in 2016.

An associate professor of Neurology at Harvard Medical School, Talkowski adds, «Individuals in 10 countries — clinicians, investigators, patients and family members — helped us assemble the largest group of arhinia patients every studied, encompassing 24 percent of the previously reported 80 individuals and 21 newly identified patients.

(This could mean that the studies weren't set up to avoid bias, or that the measures were not reported in the investigator brochures, for instance to keep the packets concise.)

Investigators report today that starting antiretroviral therapy early reduced HIV transmission by 93 percent over the course of the study.

Dr. Criner, who served as the study's Principal Investigator, will report the results on May 18 at the American Thoracic Society's annual international scientific meeting in San Diego, with simultaneous publication of the findings online in The New England Journal of Medicine.

The documentation ranges across the whole spectrum of drug development: Investigators» brochures provide information on all that is currently known about the medicine and so need periodic updating; accurate and concise protocols are required to ensure that trials are performed effectively; clinical trial reports (generally from phase II and III studies) present the information gathered from the trials; higher level documents provide summaries of efficacy and safety data from clinical trial programmes; expert reports provide critical interpretation of the results; and response documents clarify any points that are not clear to the regulatory agencies or provide additional analyses or supporting data for any items of concern.

Once the investigators reported their landmark data in 2011, all infected study participants were offered the opportunity to begin antiretroviral therapy right away, and the trial continued for another four years, concluding this spring.

High - intensity exercise can help stable heart transplant patients reach higher levels of exercise capacity, and gain better control of their blood pressure than moderate intensity exercise, investigators report in a new study published in the American Journal of Transplantation.

These recall studies are tricky, even for the mostcareful investigators, since self - reporting is often inaccurate.

Principle investigator Matthew Berg, associate professor of physics, said the study, published in Nature's Scientific Reports, is key to understanding the aerosol composition of Earth's atmosphere.

The investigators in at least one widely reported study did not look at vitamin D blood levels or supplement intake at all.

While acknowledging that NIH had not yet had time to study the report and decide on a course of action, Kirschstein insisted that «the will is there to assure that younger investigators will have the ability to develop their careers.?

This week in the Journal of Chemical Physics, from AIP Publishing, a group of investigators reports studies of the impact of secondary electrons on a model of DNA.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

In their paper published in the journal Pediatrics, Massachusetts General Hospital (MGH) investigators Shane Shucheng Wong, MD, and Timothy Wilens, MD — both of the MGH Department of Psychiatry — report that their review suggests only two pediatric uses of medical cannabis — to relieve chemotherapy - induced nausea and vomiting and to reduce seizures — are supported by existing studies.

This study, reported in a special issue of LSE, was led by Rebekah L. Layton in the UNC Office of Graduate Education and principal investigator Melanie Sinche, formerly of the Labor & Worklife Program at Harvard Law School, currently with The Jackson Laboratory.

Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal body mass index (BMI), investigators report in a study published in Lancet Oncology of 1,918 patients in six independent clinical cohorts.

«Although many reports have addressed the effect of lactic acid bacteria on skin properties in subjects with skin diseases, such as atopic dermatitis, few studies have involved healthy humans,» explains lead investigator Hiromi Kimoto - Nira, PhD, of the National Agriculture and Food Research Organization (NARO) Institute of Livestock and Grassland Science (NILGS), Tsukuba, Japan.

Turner served as principal investigator for MUSC in the VIPS for the Non-Invasive Detection of Hemispheric Bioimpedance Asymmetry in Severe Brain Pathology (VITAL) study reported in the article.

The reported incidence of gut maladies in people with autism varies wildly between published studies — from zero to more than 80 % — making it difficult to establish just how commonly the two conditions go together, says principal investigator Sarkis Mazmanian, a microbiologist at the California Institute of Technology (Caltech) in Pasadena.

In a report on the mouse studies, published online Sept. 11 in PNAS (Proceedings of the National Academy of Sciences of the United States of America), the investigators say the genetic alteration appears to release the biochemical «brakes» on brain cells involved in body movement, reasoning and perception of the world, triggering over-excited activity and reactions.

«To our knowledge this is the first report of HRQoL outcomes of men on AS for prostate cancer compared to men without prostate cancer in a prospective, multi-institutional study,» explained lead investigator Christopher R. Porter, MD, FACS, Virginia Mason Medical Center, Seattle, WA.

Of the 14 study participants found to have OSA, 12 women had mild sleep apnea and 2 had moderately severe apnea, the investigators reported.

«And 95 % of these responses are ongoing,» reported study investigator, Jeffrey Weber, MD, Lee Moffitt Cancer Center, adding that, «In my view nivolumab should replace chemotherapy in routine practice in second - or third - line treatment for melanoma patients.»

The presentation, entitled «Ibudilast — Phosphodiesterase Type 4 Inhibitor — Bi-Modal Therapy with Riluzole in Early Cohort and Advanced Amyotrophic Lateral Sclerosis (ALS) Patients — Final Report and Future Directions «(Source) will be presented by principal investigator of the clinical study, Dr. Benjamin Rix Brooks, of the Carolinas HealthCare System's Neuromuscular / ALS - MDA Center at Carolinas HealthCare System Neurosciences Institute.

«This study differs from what's been reported previously about brain neurons that control the gastrointestinal tract,» said R. Alberto Travagli, professor, Department of Neural and Behavioral Sciences, and lead investigator.

These types of reports (of which this is the second) can complement results from studies in much larger numbers of volunteers being generated by investigators based in European and African countries.

Now, in a study published in Stem Cells, the laboratory of Seung Hyun Kim (Hanyang University, Seoul, Korea) report on an open ‐ label, single ‐ arm, investigator ‐ initiated trial to identify biological markers of MSCs to predict response to in patients with ALS [3].

Advancing age of the fathers, the investigators reported, accounted for 26 percent of the cases of schizophrenia in the study; for fathers over 50, two out of every three cases of the illness could be attributed to the father's age.

Genome Atlas Group Reports on Brain Cancer Genes Johns Hopkins Kimmel Cancer Center investigators were part of The Cancer Genome Atlas (TCGA) which reported results from its first comprehensive study focused on the deadly brain cancer glioblastoma.

In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry (JBC), investigators at the Medical University of South Carolina (MUSC) and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal kidney development characteristic of polycystic kidney disease (PKD).

Although investigators have not yet identified which cells carry Sema4a in tumors and boost regulatory T cell function, the scientists did report that immune cells called plasmacytoid dendritic cells (pDCs) provided more than half of the Sema4a in tumors in this study.

But, «the type of treatment effects reported in this study, even though the investigators referred to increases in levels of «hyperactivity,» were not the disruptive excessive hyperactivity behaviors of ADHD but more likely the type of overactivity exhibited occasionally by the general population of preschool and school age children.»

«We've detected bits of «meteor smoke» embedded in noctilucent clouds,» reports James Russell of Hampton University, principal investigator of NASA's AIM mission to study the phenomenon.

As principal investigator for the study, I provided the gathering with key findings: many, many young people were dropping out of Texas schools, most schools reported no plans to address the fact that one out of three students were leaving school before obtaining a high school diploma, and the costs of undereducation to dropouts, their families and the state were enormous.

Some groundbreaking findings from this study appear in a recent paper in PLoS Genetics, «Genome - wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers» (http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004922) From work performed in Dr Lindblad - Toh's lab, the investigators report that they have identified two loci that together contribute approximately 20 % of the risk of developing hemangiosarcoma and lymphoma in Golstudy appear in a recent paper in PLoS Genetics, «Genome - wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers» (http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004922) From work performed in Dr Lindblad - Toh's lab, the investigators report that they have identified two loci that together contribute approximately 20 % of the risk of developing hemangiosarcoma and lymphoma in GolStudy Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers» (http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004922) From work performed in Dr Lindblad - Toh's lab, the investigators report that they have identified two loci that together contribute approximately 20 % of the risk of developing hemangiosarcoma and lymphoma in Goldens.