Generating NPCs in the lab, scientists believe, will offer a new way to
study kidney development and eventually treat kidney diseases.
Not exact matches
Researchers modeled
kidney development and injury in
kidney organoids (shown here), demonstrating that the organoid culture system can be used to
study mechanisms of human
kidney development and toxicity.
Studies in the mouse model further suggest that controlled expression of Lin28 can promote
kidney development and therefore may hold clues to regeneration of damaged
kidneys in adults.
«We analyzed human
kidney development, identifying features that distinguish our
kidney from its well -
studied mouse counterpart.
«Mouse and human
kidney development compared: Findings may lead to advances in the
study and treatment of
kidney disease.»
«We were
studying the role of these genes in the
development of the vasculature of the
kidney,» she recalled.
Their analysis included data from the Coronary Artery Risk
Development in Young Adults (CARDIA)
study, which contained repeated assessments of marijuana use and
kidney outcomes.
Current applications include
studies related to carbon sequestration, as well as the
development of biomarkers for breast and brain cancer, neurological diseases, and diabetes and
kidney diseases, among others.
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Study Uncovered about E-Cigarette Use NJBiz.com - December 9, 2015 Identification of Barrier that Prevents Progression of Benign
Kidney Tumors to Malignant Disease MedicalNewsToday.com - November, 24, 2015 What is the Color of the Lung Cancer Ribbon?
4/22/2008 Fat - Cell Hormone Linked to
Kidney Disease Reduced levels of a hormone produced by fat cells and linked to the development of insulin resistance may also be related to a higher risk of kidney disease, according to a study led by researchers at the University of California, San Diego School of... M
Kidney Disease Reduced levels of a hormone produced by fat cells and linked to the
development of insulin resistance may also be related to a higher risk of
kidney disease, according to a study led by researchers at the University of California, San Diego School of... M
kidney disease, according to a
study led by researchers at the University of California, San Diego School of... More...
While mouse has been successfully used to
study multiple aspects of
kidney development, the amphibian pronephros of Xenopus offers a valuable alternative to explore the underlying molecular and cellular mechanisms.
In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry (JBC), investigators at the Medical University of South Carolina (MUSC) and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo
studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal
kidney development characteristic of polycystic
kidney disease (PKD).
Our biological
studies suggest that a critically reduced amount of this protein alters cell shape, migration, proliferation, and gene expression to the detriment of brain, heart, and
kidney development.
A combination of limited human data and a wealth of animal
studies show that phthalates, as only one of many chemicals in fragrances, can impair reproduction and
development, alter liver and
kidney function, damage the heart and lungs, and effect blood clotting.
More recent nutritional
studies helped in the
development of guidelines for the dietary management of
kidney disease, a major problem in older cats.
Avoid «Senior» Diets That Have Reduced Levels of Protein
Studies have shown that the protein requirement for older dogs does not decrease with age, and that protein levels do not contribute to the
development or progression of renal (
kidney) failure.
These include the latest clinical
studies on emerging
developments in renal medicine and the highest level of original research
studies in therapy and epidemiology of acute and chronic
kidney failure, as well as their translational aspects and genetic basis.