I asked this question hundreds of times as I called child care centers throughout New Jersey as part of a statewide
study on the availability of center - based care for infants and toddlers
We started 2017 off strong with a comprehensive
study on the availability of shelter dogs in our country, showing that far fewer than previously thought are actually available for adoption.
Not exact matches
Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and
studies of eptinezumab sufficient to achieve a positive completion; the
availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing
on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report
on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC)
on February 26, 2018, and is available
on the SEC's website at www.sec.gov.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required
on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration;
availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical
studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact
on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
According to Living Goods, clients may also be reluctant to buy drugs from other private providers because of the risk of getting a counterfeit medicine.63 Living Goods sent us a
study conducted at the midline of its RCT that claims that both
availability of counterfeit drugs and drug prices decreased at private retailers in areas where CHPs worked.64 According to the
study, about 37 % of private drug shops in the areas it
studied sold fake ACT drugs, 65 and availabilty of fake ACTs was about 50 % lower among non-Living Goods sellers in the areas where Living Goods worked.66 Additional results
on these potential effects will be made available when the full RCT is published.
In the current
study, we provide novel data
on changes in the
availability of added and refined sugars and in recorded intakes of total sugars, added sugars, SSB, carbonated soft drinks, juices, confectionery, and alcohol consumption in Australian adults and children between the 2 most recent national dietary surveys in 1995 and 2011 — 2012.
Manhattan Borough President Scott Stringer wants to require developers to look at the
availability of food and supermarkets when embarking
on their land use
studies.
At 11 a.m., the U.S. Department of Homeland Security and the MTA hold a joint media
availability to discuss the Underground Transport Restoration subway airflow
studies to take place from May 9 to May 13, 34th St. - Penn Station
on the ACE Line, Lower Mezzanine, Manhattan.
The idea that productivity is limited by the
availability of nutrients is based mainly
on studies in surface waters.
Writing in a linked Comment, Gino Vumbaca from Harm Reduction Australia, said: «Evidence
on the effectiveness of compulsory and voluntary drug dependence treatment in the Asian region has been scarce and this
study is a much needed addition to the evidence base that is required to inform policy making... The present
study provides solid evidence in support of urgent need to expand
availability of and access to evidence based voluntary drug dependence treatment approaches to all whom are affected by drug dependence.
While other
studies have examined the tanning habits of college students, no
study has examined the
availability of tanning salons
on or near college campuses, according to background information in the
study.
In his
study, published in
Availability, Reliability and Security, he explains that the dramatic shift in power between a country and an individual is very enticing and it's one sign that a cyber terrorism community could be
on the rise.
Specification of where all data underlying the
study are available, or will be deposited, and whether there are any restrictions
on data
availability such as an MTA.
Previous
studies have suggested that temperature and, more specifically, atmospheric carbon dioxide levels influence body size more via an indirect impact
on food
availability and nutritional content.
This is one of the few
studies to have examined the online
availability of antibiotics and to have explored the potential effects
on public health.
According to the researchers, the importance of their
study is elevated by the large amount of previous work
on the same interval and thus the extensive
availability of supporting data and samples.
Dr Victoria Leong, lead author
on the
study said: «When the adult and infant are looking at each other, they are signalling their
availability and intention to communicate with each other.
The success of fast - food menu labeling depends
on multiple conditions being met, not just the
availability of calorie information,» said
study author Andrew Breck, a doctoral candidate at NYU Wagner Graduate School of Public Service.
Besides its
availability on the Informed Consent Project website, the
study can be read in the online Journal of Health Politics, Policy and Law published by Duke University Press.
«Obesity and Type 2 diabetes in children is
on the rise and there is the argument that it is related to lifestyle and
availability of high calorie foods and reduced physical activity, but our
study has found that maternal antidepressant use may also be a contributing factor to the obesity and diabetes epidemic,» said the
study's senior investigator Alison Holloway, associate professor of obstetrics and gynecology at McMaster University.
The
study compared the influence of pH, resource
availability, temperature, distance from shore, and depth
on accretion - erosion balance.
The
study, published this month in the journal of Urban Forestry & Urban Greening, draws
on Seattle's current land use, light
availability and national nutritional guidelines to determine the city's carrying capacity for feeding its population.
While biofuels from crops, grasses, wood, agricultural residues and other materials emit less carbon than fossil fuels over a crop - to - vehicle life cycle, recent
studies have questioned the
availability of material to make fuels
on a large scale.
A recent
study published in Scientific Reports, led by researchers of the University of Barcelona in collaboration with several other research institutions, shows that the direct effect of climate change in regulating fuel moisture (droughts leading to larger fires) is expected to be dominant, regarding the indirect effect of antecedent climate
on fuel load and structure - that is, warmer / drier conditions that determine fuel
availability.
To examine how the
availability of food may have affected armed conflict in Africa, the
study relies
on PRIO - Grid data from over 10,600 grid cells in Africa from 1998 to 2008, new agricultural yields data from EarthStat and Armed Conflict Location and Event Dataset, which documents incidents of political violence, including those with and without casualties.
The research, made possible by the
availability of high - resolution data in space and time
on veterinarian movements in the
study area, shed light
on the actual significance of operator movements in disease spread, a still poorly understood topic due to the highly diverse and complex nature of such movements and to privacy issues in data collection.
The finding from this
study — that the increased
availability of food
on deep - sea hills is fuelling increased seafloor biomass — is important because there are approximately 25 million abyssal hills and seamounts — they are thought to be the most common landform
on the planet.»
That decision followed a
study requested by electronics companies
on the
availability of high - performance computers from outside the COCOM countries.
In this latest
study, the team of researchers applied empirical and process - based models, to analyze local areas, as well as the global surface, and the effect of temperature and water
availability variations
on carbon exchange between the atmosphere and the terrestrial biosphere.
On a more localized level, however, the
study suggests that water
availability is the dominant factor in determining how successfully carbon sinks are performing.
«This
study addresses one of the most relevant issues in healthcare and research
on aging populations: how to diagnose and assess frailty, given the
availability of many different frailty scores and the lack of a gold standard», says Dr Aguayo.
A Kansas State University
study focuses
on future
availability of groundwater in the High Plains Aquifer.
Impact of sugarcane bagasse - derived biochar
on heavy metal
availability and microbial activity: A field
study — Chengrong Nie — Chemosphere
An in vivo - vitro shuttle system for the
study of P. cynomolgi liver stages12 is being exploited to better understand hypnozoite biology using molecular tools and genome - scale approaches, which rely
on the
availability of a complete and well annotated P. cynomolgi reference genome sequence.
In this
study, women featured increased NO
availability and reduced renal oxidative stress than their male counterparts, which might have protective effects
on progression of diabetic renal impairment (332).
The
study builds
on an earlier map, produced by paper co-authors Ximing Cai, Xiao Zhang, and Dingbao Wang, which had provided a new global estimate for land
availability.
Efficacy
studies depend
on the
availability of the challenge model and can be performed in biosafety containment up to BSL3.
This is the first genome sequence of the T. equiperdum species, and its
availability will provide important insights for future
studies on genetic classification of the subgenus Trypanozoon.
With the current
study, the authors built
on that work, analyzing the planet's nitrogen balance, geochemical proxies and building a spatial nitrogen weathering model to assess rock nitrogen
availability on a global scale.
The
study, part of the Gallup - Healthways State of American Well - Being Series, assigned an «Active Living» score to cities based
on factors like walkability, bike - ability, the quality of the public transit system, and
availability of well - maintained parks.
«While there have been many
studies linking alcohol and drug use by parents to substance use among youths, there is limited research
on how the
availability of alcohol and drugs in the home may influence patterns of use among offspring in the future,» Broman said in a university news release.
A
study of Asian vegetarians with incomplete amino acid intake showed reduced clearing of xenobiotics.47 Low levels of hydrochloric acid have an adverse impact
on the
availability of dietary amino acids, even in a higher protein diet, so stimulating the pancreas using lacto - fermented foods is crucial.
While this
study was lab - based and not conducted
on real people eating real food, we look forward to future
studies that may show the ability of beta - carotene content in our plant foods to improve the
availability of minerals in those foods like iron and zinc.
A new
study by UNESCO's Global Education Monitoring Report (GEM) * to be issued
on 19 January proposes an economic model that would help reduce the cost of textbooks and increase their
availability to students in schools around the world.
The project is a response to concerns about the
availability of inappropriate content to school children - A new
study from researchers at the University of Oxford casts serious doubt
on the effectiveness of internet filtering, suggesting that, while parents are reassured by adding filtering to their domestic gadgets, both the suppliers and consumers of inappropriate content can easily find ways around it.
LaunchPath's goal is to improve the quality and scale of work - based learning by using a comprehensive data system to seamlessly match students and employers based
on students» fields of
study and employers»
availability.
This brief highlights limitations of district - level data
on principals encountered during data collection for a
study on principal preparation programs and describes the importance of improving the accuracy and
availability of these data.
The following aspects of the context were observed across both
studies: the presence of a principal with drive and enthusiasm, the
availability of school resources in the form of both human and technical resources, a strongly supportive school culture in which the expectation that staff would come
on board was strong, and collegial support to help this happen.
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availability of this vehicle.