Sentences with phrase «study protocols which»

Not exact matches

In parallel, adjudication will be completed for all MACE which occurred during the study, including adjudication for certain events which, per protocol, can not be finally adjudicated until patients complete their final site visit and results are available from certain non-invasive diagnostic testing conducted during such site visits.
It appears that other types of protocols are utilized by the WHO, such as for the newly released Intrapartum Care for Positive Childbirth Experience, which includes all types of quantitative research, for example observational studies, and is not limited to RCTs.
Companies list projects, which «can range from an hourlong phone call — you want to speak with an expert in CRISPR --[to hiring] a postdoc for 3 weeks to build you a protocol for your clinical study,» he explains.
«Rather than focusing on total numbers of published reports, reviews of academic performance should explicitly take into account the proportion of a researcher's initiated studies (e.g., those receiving ethics approval or funding) that have been reported, for which protocols have been shared, and that have had their dataset reused by other researchers.»
This protocol has been successfully applied to the high incorporation of deuterium and tritium in 18 drug molecules, which meet the requirements for use in ligand - binding assays and absorption, distribution, metabolism, and excretion studies.
Before and during the 35 - week standard treatment protocolwhich was not altered for the current study — MR images were taken with the high - power 3T scanner at the MGH - based Martinos Center for Biomedical Imaging.
In the 2014 soccer World Cup, concussion assessment protocols were not followed in more than 60 percent of plays in which players involved in head collisions were not assessed by sideline health care personnel, according to a study published by JAMA.
Professor Elaine Dennison, Professor of Musculoskeletal Epidemiology and Honorary Consultant in Rheumatology within Medicine at the University of Southampton, noted: «Among the challenges in carrying out this study was the great heterogeneity in the RCTs, including in the exercise protocols and in the dosage of supplementation, all of which contributes to the variable findings between studies.
Although no prototype has yet been built, Ibanez de Alba has already obtained a «viability protocol» — a study which outlines construction and installation procedures — from Dragados y Construccines, one of Spain's major construction companies.
The new protocols of sequencing and analysis allow us to extract quite more information than in previous studies, which were limited to specific regions or surface waters, to an unprecedented level of resolution.»
Other studies which have assessed the importance of the Montreal Protocol have used models to predict atmospheric winds and temperatures and have looked a few decades into the future.
This task has been used in several studies showing recruitment of the medial temporal lobe during navigation.28 - 30 The study was performed in accordance with the protocol (available at NEJM.org), which includes mention of a test of deep - brain stimulation during egocentric training; we have yet to carry out this part of the protocol.
The Children's Oncology Group (COG) Supportive Care Guidelines Committee is an inter-professional committee of pediatric hematology / oncology health care professionals which identifies rigorously developed, evidence - based, supportive care guidelines and evaluate them for endorsement by the COG and incorporation into COG study protocols.
Before conducting a study, scientists should «preregister» their research protocols by posting the intended methodology online, which eliminates opportunities for changing the rules in the middle of the experiment.
The stated enrollment goals suggest the intent to recruit all subjects from the original trial into both studies, which appears to be impossible per the stated protocols.
It is also unclear why results are not presented for the MDS - UPDRS Ia subscale or for cognition, which were both listed in the study protocol as secondary outcomes.
Methods: We performed a cross-sectional study in which 97 healthy participants, 34 with aMCI, and 33 with mild AD were studied with LASSI - L and a comprehensive neuropsychological protocol.
They stated that future studies may benefit from incorporating protocol refinements such as those described here, which include global capture of function, control for potential confounds, and investigation of underlying neural substrates of recovery.
The study protocol was approved by the KPNC institutional review board and the California State Committee for the Protection of Human Subjects, which waived written consent for participants because our data - only study had no direct contact with patients.
The Ethics Committee of the Federal University of São Paulo previously approved the study protocol, which followed the tenets of the Declaration of Helsinki.32
The expert review panel recommended one practice guideline based on a 2005 randomized trial that provided data to support a memory retraining protocol.12, 13 The trial enrolled 29 subjects with MS - related learning deficits and randomized them to either the control group (n = 14) or the experimental group (n = 15).13 Both groups participated in 8 «treatment» sessions, which consisted of nontraining memory tasks for the control group and the Story Memory Technique (SMT), which taught the skills of visualization and context to improve learning, for the experimental group.13 In subjects with moderately severe impairment, 88 % in the experimental group showed significant improvement in learning abilities compared with 38 % in the control group (P <.01).13 Subjects with mild impairment showed little improvement.13 On this basis, the technique used in this study was recommended by the review panel as a practice guideline for the rehabilitation of learning and memory in persons with MS. 12
For example, one study that set out to determine which type of training was most beneficial for the brain, had one untrained test subject who underwent different training routines — a jogging protocol for one week, a lifting protocol for one week, and HIIT protocol for one week.
Conversely, the extended fasting periods associated with total IER (100 % ER / alternate days) protocols have been linked to worsening post-prandial glucose control in women.32 It will thus be of interest to study and directly compare the metabolic effects of IER protocols which vary in frequency, duration and severity of ER periods.
Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions
Two hormonal regulators which have been studied are leptin and ghrelin, whose effects on energy balance are in a large part mediated by the hypothalamus.87 Leptin, a peptide hormone secreted by adipose tissue, acts to reduce appetite.87 Circulating levels are proportional to adiposity and so decline during weight - loss, thus increasing appetite, however this reduction is believed to be disproportionately greater than the change in fat - mass.82 As expected, IER (60 - 85 % ER on restricted days) weight - loss interventions have all noted a decline in leptin levels 39, 41, 46 - 49, 52, comparable with energy - matched CER protocols after three months 48 and six months.41
Persistent hunger and irritability noted in non-obese men and women in earlier IER trials, where food was completely restricted on alternate days, suggest that some individuals are unlikely to be able to comply for extended periods of time.33 Compliance with IER protocols which allow some intake on restricted days have been promisingly high.38, 43, 48, 49, 51, 52 Additionally, several studies have also demonstrated a lack of compensatory hyperphagia 38, 39, 41, 48, 52, 84 upon resumption of free - eating which, if were to occur, would be expected to limit the efficacy of IER as a weight loss / maintenance strategy.
demonstrated that with proper volume protocols, high rep and low rep groups gain muscle at the same rate in their first 3 months of training, which renders the findings of this study irrelevant.
I'm going to be writing a post on this soon, but I just came across a study which I was really excited about that showed that botanical protocols are more effective than Rifaximin, which is the drug of choice for SIBO, and not only are they more effective, they're, of course, much safer, they don't tend to produce as many side effects, nor do they have as negative of an impact on the gut flora, and they're even effective in people who have done Rifaximin and haven't had success with it.
This post does detail the healing affects of long term dietary protocols that achieved remission or management of chronic disease and identifies the state of the art studies of such with a focus on autism and IBD, most likely due to changing up the microbiome which altered health.
The most significant new piece of news in the article is that Wilson and his colleagues have just finished a follow - up study, in which they used the exact same protocol to study dynamic stretching.
And not by reading journals and studies, which are usually vague at best in describing the protocol being used.
* Duration of a few weeks * An average dose more equivocal to a «loading» phase than a «maintenance phase» * A larger dose for potential responders who lack natural, dietary creatine * A smaller dose for potential non-responders with a significant amount of existing dietary creatine intake * A training protocol that emphasizes all phases of muscular energetics to take advantage of the ATP - CP, glycolytic, and oxidative effects of creatine supplementation (HIIT is ideal for cardiovascular exercise when supplementing creatine, due to the repeated bouts of high intensity work) * A training protocol that incorporates negatives in order to stimulate satellite cell fusion, as per Dr. Hatfield's theory of holistic training * A training protocol that emphasizes repeated bouts of work per the results of creatine studies * A nutrition protocol tailored to reduce post-workout cortisol levels, which would involve a post-workout shake and possible glutamine supplementation * A nutrition protocol that takes advantage of carb - load (super compensation) near the end of the cycle
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While the findings are mixed, this is consistent with many studies of new interventions in yoga and elsewhere in which researchers are eager to test the effects of their newly developed protocols.
To achieve this objective, the macronutrient content of the 2 diets was strictly controlled, unlike the protocol in other studies, in which fat or protein content was allowed to vary over the experimental periods (11 — 13).
In fact, studies show that the heavy weight exercise protocols appear to greatly increase plasma beta - endorphin concentration, which in turn modulates mood in a positive manner.
The iQUEST Collaborative Lesson Study (Bransford et al., 1999) protocol builds a community of practice in which teachers routinely share collaboratively developed lessons and share their learning, working in teams facilitated by a project leader.
It is also processes, which may range from lesson study to a protocol for visiting classrooms.
The results of the study may help to diagnose CHF earlier, better stratify cardiovascular risk, tailor therapy to specific dog needs, and reduce the exposure of radiation required for repeated thoracic radiography, which is current protocol.
The test protocol, which is a result of the 2013 Harness Crashworthiness Study conducted by Center for Pet Safety, outlines a consistent test methodology and evaluation program to ensure pet safety harness restraints offer crash protection.
The preponderance of the evidence shown by these studies indicates that the implementation of training and / or behavior modification protocols predicated upon «dominance theory» and social structures («alpha,» or «leader of pack»), usage of physical or mental force, intimidation, coercion or fear are empirically less effective and often create as a consequence «fallout» behaviors — behaviors which may be dangerous to the human and animal involved.
While all large commercial banks have, of course, also increased their renewables finance over the past few years, our study finds that this pales in comparison to their finance for the coal sector, which has grown by almost 400 % since 2005, the year the Kyoto Protocol came into force.
Equipment is miscalibrated, protocols are not scrupulously followed, it happens and when it does the appropriate response is to allow for it, quantify the effect on the conclusions if possible, attempt to reproduce the study using the raw data (which anyone could do and nobody has, to my knowledge).
The starting point is an analysis of the requirements as established mainly in IGACO theme and in the «CAPACITY» study which in turn builds in GMES, DUE and EUMETSAT related activities, the requirements derived from the need to monitor the implementation of the Montreal and Kyoto protocols, and the requirements of the Global Atmospheric Watch.
The effects of an agreement such as the Kyoto Protocol, which implicitly imposes a ceiling on the stock of pollution, have recently been studied in Hotelling models.
Still, Canada is the only industrialized country not party to the protocol, according to the CIPO, which is studying the implications of the protocol, but has not made a decision about whether to join.
The cost to researchers for having to develop protocols which protect protected health information is difficult to estimate, but the Department assumes that each of the affected 76,609 studies will require an average of an additional 8 hours of time for protocol development and implementation.
Completed full Site Management which entailed accounting for study medication in Clinphone system, Ensuring all data in CTMS is accurate, verifying drug accountability, completing drug inventory / ensuring drug maintained in locked limited access environment with temperature range / Temp Logs, completed 100 % SDV, completed query reconciliation trained site staff on EDC system, protocol, GCP Guidelines, etc..
Prepared and maintained approved studies for compliance with the FDA, IRB and sponsors requirements which includes IND Safety Reports, SAE Reports, protocol deviations and FDA 1572 forms.
Embedded Wireless Architecture • Designed and developed RF communication protocol and MAC layer which included scrambling, error detection and correction through Linear block coding • Implemented hardware for MAC layer using RF transceiver modules and studied related spectrum characteristics • Gained proficiency with spread spectrum analysis which is utilized in 802.11 b / g / n IEEE protocol for wireless LAN
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