Sentences with phrase «study regulation of gene expression»

Tapscott applies the method to study regulation of gene expression in normal development of muscle tissue, while Olson uses it to identify genetic profiles of brain - cancer development.
Marek is performing postdoctoral research in the lab of Nick Ingolia at UC Berkeley studying the regulation of gene expression.
The Kind group studies the regulation of gene expression in single cells by developing and using novel microscopy and genomics based techniques.

Not exact matches

Booij and her colleagues hope that this study will shed more light on the specific role of early environmental influences on brain development, gene expression and emotional regulation.
The regulation of gene expression, for example, is extremely difficult to study through the genome alone.
The modern study of gene regulation started in the 1950s, but researchers only started to unravel the complex array of histone modifications that fine - tune chromatin control of gene expression 20 years ago.
Embryonic development is a well - studied process in which the precise regulation of gene expression is critical, since many genes are expressed simultaneously and in a punctual manner.
In a study published online in Genome Research, researchers devised a strategy for genome - wide annotation of primary miRNA transcripts, providing extensive new annotations in human and mouse, and shedding light on mechanisms of regulation of microRNA gene expression.
Our technological expertise ranges from the most fundamental approaches to study membrane transport in lymphocytes and dendritic cells (subcellular compartmentalization, intravital microscopy, phagosomal functions), the systematic analysis of gene expression and it regulation (RNAseq, Chip Seq, proteomics) and physiological and pathological immune responses (mouse models for cancer immunity, immunomodulation / vaccination, human clinical studies in cancer).
We have also initiated studies of the regulation of cytokine gene expression in these cells.
The initial work was mainly focused on the study of the regulation of muscle chromatin and gene expression by motor innervation.
Transcriptome studies such as the National Institute of Health's Genotype - Tissue Expression (GTEx) program aim to overcome this limitation by studying gene expression levels and regulation mechanisms and their relationship with diseases, instead of only DNAExpression (GTEx) program aim to overcome this limitation by studying gene expression levels and regulation mechanisms and their relationship with diseases, instead of only DNAexpression levels and regulation mechanisms and their relationship with diseases, instead of only DNA sequence.
These studies are unable to determine a causal relationship due to factors such as gene regulation — a genetic variant may instead contribute to altered expression levels of true causal genes, which remain undetected by a GWAS.
In this study, we also identify p21waf1 / cip1 as a target gene of DDX3, and the up - regulation of p21waf1 / cip1 expression is linked to the growth - suppressive effect exerted by DDX3 (see Fig. 2).
She obtained her PhD in molecular biomedicine from University of Tartu studying the genetic regulation of gene expression.
The main research focus of the single molecule group is the study of molecular motors, the role of force in regulating biological systems, and the molecular mechanisms of gene expression regulation.
- The work, published in Nature Genetics, represents an important advance in our understanding of gene regulation and reveals a new layer of complexity that needs to be studied to properly interpret genomics and gene expression in the future.
A comprehensive study of gene expression in tomato fruits will explore unanswered questions about gene regulation, hormonal control and structural polymers that make up cell walls in fruits, to improve crop quality and yields.
To uncover molecular processes in individual cells and to understand the full complexity of biological systems, our lab applies and develops novel microscopy and genomics based techniques to study the regulation of gene - expression in single cells.
This appears in the latest study from the lab of Rugang Zhang, Ph.D., deputy director of The Wistar Institute Cancer Center, professor and co-program leader of the Gene Expression and Regulation Program.
Betsy M. Martinez - Vaz, Irina Makarevitch, Shane Stensland (2010) Studying Gene Expression: Database Searches and Promoter Fusions to Investigate Transcriptional Regulation in Bacteria Journal of microbiology and biology education.
The SMF's microarray service offers a comprehensive set of integrated gene expression services that facilitate studying the role of genomic alterations and transcriptional regulation of genes.
Studies to date have demonstrated that phytochemicals in common fruit and vegetables can have complementary and overlapping mechanisms of action, including modulation of detoxification enzymes, scavenging of oxidative agents, stimulation of the immune system, regulation of gene expression in cell proliferation and apoptosis, hormone metabolism, and antibacterial and antiviral effects (15, 16).
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