Tapscott applies the method to
study regulation of gene expression in normal development of muscle tissue, while Olson uses it to identify genetic profiles of brain - cancer development.
Marek is performing postdoctoral research in the lab of Nick Ingolia at UC Berkeley
studying the regulation of gene expression.
The Kind group
studies the regulation of gene expression in single cells by developing and using novel microscopy and genomics based techniques.
Not exact matches
Booij and her colleagues hope that this
study will shed more light on the specific role
of early environmental influences on brain development,
gene expression and emotional
regulation.
The
regulation of gene expression, for example, is extremely difficult to
study through the genome alone.
The modern
study of gene regulation started in the 1950s, but researchers only started to unravel the complex array
of histone modifications that fine - tune chromatin control
of gene expression 20 years ago.
Embryonic development is a well -
studied process in which the precise
regulation of gene expression is critical, since many
genes are expressed simultaneously and in a punctual manner.
In a
study published online in Genome Research, researchers devised a strategy for genome - wide annotation
of primary miRNA transcripts, providing extensive new annotations in human and mouse, and shedding light on mechanisms
of regulation of microRNA
gene expression.
Our technological expertise ranges from the most fundamental approaches to
study membrane transport in lymphocytes and dendritic cells (subcellular compartmentalization, intravital microscopy, phagosomal functions), the systematic analysis
of gene expression and it
regulation (RNAseq, Chip Seq, proteomics) and physiological and pathological immune responses (mouse models for cancer immunity, immunomodulation / vaccination, human clinical
studies in cancer).
We have also initiated
studies of the
regulation of cytokine
gene expression in these cells.
The initial work was mainly focused on the
study of the
regulation of muscle chromatin and
gene expression by motor innervation.
Transcriptome
studies such as the National Institute
of Health's Genotype - Tissue
Expression (GTEx) program aim to overcome this limitation by studying gene expression levels and regulation mechanisms and their relationship with diseases, instead of only DNA
Expression (GTEx) program aim to overcome this limitation by
studying gene expression levels and regulation mechanisms and their relationship with diseases, instead of only DNA
expression levels and
regulation mechanisms and their relationship with diseases, instead
of only DNA sequence.
These
studies are unable to determine a causal relationship due to factors such as
gene regulation — a genetic variant may instead contribute to altered
expression levels
of true causal
genes, which remain undetected by a GWAS.
In this
study, we also identify p21waf1 / cip1 as a target
gene of DDX3, and the up -
regulation of p21waf1 / cip1
expression is linked to the growth - suppressive effect exerted by DDX3 (see Fig. 2).
She obtained her PhD in molecular biomedicine from University
of Tartu
studying the genetic
regulation of gene expression.
The main research focus
of the single molecule group is the
study of molecular motors, the role
of force in regulating biological systems, and the molecular mechanisms
of gene expression regulation.
- The work, published in Nature Genetics, represents an important advance in our understanding
of gene regulation and reveals a new layer
of complexity that needs to be
studied to properly interpret genomics and
gene expression in the future.
A comprehensive
study of gene expression in tomato fruits will explore unanswered questions about
gene regulation, hormonal control and structural polymers that make up cell walls in fruits, to improve crop quality and yields.
To uncover molecular processes in individual cells and to understand the full complexity
of biological systems, our lab applies and develops novel microscopy and genomics based techniques to
study the
regulation of gene -
expression in single cells.
This appears in the latest
study from the lab
of Rugang Zhang, Ph.D., deputy director
of The Wistar Institute Cancer Center, professor and co-program leader
of the
Gene Expression and
Regulation Program.
Betsy M. Martinez - Vaz, Irina Makarevitch, Shane Stensland (2010)
Studying Gene Expression: Database Searches and Promoter Fusions to Investigate Transcriptional
Regulation in Bacteria Journal
of microbiology and biology education.
The SMF's microarray service offers a comprehensive set
of integrated
gene expression services that facilitate
studying the role
of genomic alterations and transcriptional
regulation of genes.
Studies to date have demonstrated that phytochemicals in common fruit and vegetables can have complementary and overlapping mechanisms
of action, including modulation
of detoxification enzymes, scavenging
of oxidative agents, stimulation
of the immune system,
regulation of gene expression in cell proliferation and apoptosis, hormone metabolism, and antibacterial and antiviral effects (15, 16).