With this technique we can
study synaptic plasticity at its most fundamental level.
Not exact matches
Molecular
studies of gene expression during long - lasting
synaptic plasticity related to memory storage initially focused on the identification of positive regulators.
This finding is in accordance with earlier animal model
studies, which have shown that physical activity increases the amount of growth factors in the brain and improves
synaptic plasticity.
Dr. Stuart Hameroff, lead author on the new TUS
study, said: «This suggests TUS may stimulate natural megahertz resonances in brain microtubules, enhancing not only mood and conscious mental states, but perhaps also microtubule functions in
synaptic plasticity, nerve growth and repair.
A
study based on the research, «Habituation based
synaptic plasticity and organismic learning in a quantum perovskite,» appeared in the August 14 online issue of Nature Communications.
I wanted to continue to
study the hippocampus but change my focus to
synaptic plasticity.
Mice in booze camp In the new
study, performed on adolescent male mice, ethanol alcohol exposure seemed to enhance
synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathway.
Differences and details A 2005
study of ethanol exposure in mice did not find enhancement of
synaptic plasticity.
In this
study, the authors were able to show that TGF β1 triggers N - methyl - D - aspartate receptor (NMDA), a molecule controlling memory formation and maintenance through
synaptic plasticity.
Previous
studies have shown for different brain regions that the metabotropic glutamate receptor 5 (mGlu5 receptor) plays a crucial role in this long - term form of
synaptic plasticity.
We also
study how molecular signaling, translational control,
synaptic plasticity, and behavior are altered in mouse models of developmental disability, autism, aging, and Alzheimer's disease.
Using these techniques, Dr. Watanabe is
studying cellular and molecular mechanisms underlying
synaptic transmission and
synaptic plasticity.
He joined the Polleux lab in 2017 where he
studies how the endoplasmic reticulum (ER) and mitochondria networks regulate spatiotemporal dynamics of dendritic calcium in the context of
synaptic integration,
plasticity, circuit function and behavior.
Based on evidence from electrophysiological
studies showing that both
synaptic plasticity and strength of inputs to hippocampal region CA1 vary systematically with ongoing theta oscillations (Hyman et al., 2003; Brankack et al., 1993), it has been suggested that the theta rhythm functions to separate periods of encoding of current sensory stimuli and retrieval of episodic memory cued by current stimuli so as to avoid interference that would occur if encoding and retrieval were simultaneous.
This is called homeostasis, and I've been
studying that along with the
synaptic plasticity associated with learning and memory.
Using these approaches in combination with genetics, molecular biology and biochemistry, we are
studying the molecular mechanisms underlying
synaptic transmission and
plasticity in mammalian central nervous system.
Haghighi
studies synaptic growth, function and
plasticity in both normal and diseased animals, aiming to identify the very earliest malfunctions in
synaptic function.
In addition to fragile X syndrome, my laboratory also has conducted
studies to determine whether the signaling cascades that normally are required for long - lasting
synaptic plasticity and memory are altered in mouse models of several developmental disorders, iincluding autism spectrum disorder (ASD), intellectual disability (ID), tuberous sclerosis complex (TSC), and Angelman syndrome.
Numerous
studies show that BDNF plays a critical role in
synaptic plasticity and memory [68], [69].
a) In the subsection «Cell type - specific NMDA - R pharmacology in cocaine - induced
synaptic plasticity» we now more clearly introduce the Zweifel and Engblom
studies as well as the differences between them: both of which used genetic ablation of Grin1 over 1 week but showed different results with respect to DA neuron
synaptic potentiation, which was due to methodological challenges with AMP - R compensation.