Sentences with phrase «study telomeres»

Intrigued, after finishing her Ph.D. in 1983, she decided to study telomeres as a postdoc with Harvard Medical School chromosome biologist Jack Szostak.

Lundblad, a tall woman whose wavy brown hair is touched with gray, has been studying telomeres for almost 20 years.

At Baylor, he studied telomere replication proteins in yeast.

(Representative comment, from 2009 Nobel Laureate Elizabeth Blackburn, who originally studied telomeres using the protozoan Tetrahymena: «I urge you to make every possible effort to ensure that the proposed reorganization at NIH does not jeopardize the Tetrahymena stock center - it is a critical resource.»)

One Nobel Prize - winning scientist who studies telomeres has compared them to aglets — the plastic or metal sheath covering ends of shoelaces.

Not exact matches

The same study that pointed to the benefits of marriage also reported that high income is associated with longer telomeres.

Beginning as early as this spring, the companies will offer telomere - measurement tests to research centers and companies studying the role of telomeres in aging and disease; the general public may have access by the fall through doctors and laboratories, perhaps even directly.

The finding is surprising because this was not a study of telomere length.

Studies comparing the telomere length of white blood cells among groups of volunteers show distinct correlations between telomere length and lifestyle.

«With longevity and the ability to bear children at an older age associated with longer telomere length, this study suggests that a higher maternal age of successful child bearing may be a marker of healthy aging,» says Dr. JoAnn Pinkerton, NAMS executive director.

A new study, however, identifies one possible predictor — specifically, telomere length.

In this study, the proportion of women in the longest telomere tertile was higher for women in the fourth quartile of maternal age at the birth of their last child than in the first quartile (35.7 % vs 20.2 %).

The study «Telomere length is longer in women with late maternal age,» used data from LLFS to show that certain factors associated with the rate of aging and longevity, such as telomere length, are also associated with later maternal age at the birth of the lasTelomere length is longer in women with late maternal age,» used data from LLFS to show that certain factors associated with the rate of aging and longevity, such as telomere length, are also associated with later maternal age at the birth of the lastelomere length, are also associated with later maternal age at the birth of the last child.

But well - designed studies looking at telomere length and signs of health like resting heart rate have begun to provide new details concerning telomeres» effects on biological processes, which may help us establish causality in the future.

Some studies suggest there's a connection between shortened telomeres and some types of cancer, but not other types of cancer (see a comprehensive listing of papers on the Telome Health site).

For instance, one small study found that people who ate healthier diets, did yoga or meditation, and exercised daily increased the activity of telomerase, which could lead to longer telomeres.

Telomere length does seem to be linked to life span; one key study in The Lancet found that otherwise - normal people over 60 who started out the study with short telomeres were more likely to die over the next 17 years than those with long telomeres.

Some studies have shown associations between telomere length and exercise, stress, diet, and smoking.

They specifically studied the length of telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood cells); the protective caps are believed to be markers of biological aging, because they shrink over time.

The study, led by scientists from the University of Chicago, uses a novel method to measure genetic predisposition for telomere length, rather than physiological measures which are confounded by factors such as age and lifestyle.

A large - scale genetic study of the links between telomere length and risk for five common cancers finds that long telomeres are associated with an increased risk of lung adenocarcinoma.

Because telomeres can vary greatly due to factors such as age, lifestyle and cancer progression, efforts to study the direct associations between cancer risk and telomere length have been difficult.

By using this technique, we demonstrated that the telomere G - tail length of leukocytes is significantly correlated with endothelial function and severity of ARWMCs,» said Professor Hidetoshi Tahara, a principal investigator of this study at the Department of Cellular and Molecular Biology, Hiroshima University.

Izpisua Belmonte added that more extensive studies will be needed to fully understand the role of heterochromatin disorganization in aging, including how it interacts with other cellular processes implicated in aging, such as shortening of the end of chromosomes, known as telomeres.

Previous studies have linked telomeres to the function of mitochondria (essential cell organelles that act as cellular power plants) and vice versa.

The study assessed the number of children born to 75 women from two neighbouring indigenous rural Guatemalan communities, and their telomere lengths.

«The findings from our study validated recent findings on the telomere binding role of ZBTB48.

It potentially also suggests applications for the human ageing process even at old age when telomere length has already decreased,» said Dr Grishma Rane, Research Fellow at CSI Singapore and co-first author of the study.

With the discovery of ZBTB48's novel linkage between telomeres and mitochondria, which both have key roles in cellular ageing, we will also be studying whether this interplay contributes to telomere maintenance.»

Subsequent studies have shown that shortened telomeres are linked to many age - related diseases, including heart disease, diabetes, Alzheimer's, stroke and obstructive lung disease.

The length of telomeres has been associated with morbidity and mortality previously, but this is the first study to examine links with having children.

Dr. Anna Z. Pollack, lead author of the study, pointed out, «with cross-sectional data, we can't tell if having children is related to shortening of telomeres or merely whether women who have children start out with shorter telomeres.»

«Previous studies have shown that genetics have an effect on the telomere length in individual birds.

Elizabeth Blackburn is the 59 - year - old Tasmanian - born scientist responsible for launching one of the hottest fields in the life sciences, the study of telomeres.

According to the researchers, their study shows that the environment in which great tits grow up determines the length of their telomeres more than their genetics.

The variant lies near a gene called telomerase RNA component, or TERC, and earlier studies in animals have shown that low TERC expression is associated with shorter telomeres, and faster biological aging.

Several recent studies report that telomeres are shorter among undersleepers.

«In mammalian cells we have only been able to study ALT in cells derived from ALT - dependent tumors,» says Karlseder, who also employs roundworm models to test ALT - dependent telomere construction.

«We've got a marker for biological aging — telomere length — so we're studying whether we can relate it to the increased risk of getting some of these age - associated diseases.

Studies comparing telomere lengths in individuals against the population as a whole suggest that shorter telomeres are linked with ill health and a shorter life.

The studies on autophagy by Yoshinori Ohsumi, which earned him the Nobel Prize in Medicine in 2016, and the discovery of cell cycle regulatory genes for which Leland Hartwell, Timothy Hunt and Paul Nurse received the same award in 2001, including the research of Elizabeth Blackburn, Carol Greider and Jack Szostak on telomeres, telomerase and its protective effect on the chromosomes, were all made possible thanks to yeast.

The study, published in the Journal of Investigative Dermatology measured the length of white blood cell telomeres in 1,205 twins from the TwinsUK cohort.

Previous studies have suggested that shorter telomeres are linked to heart disease, dementia and cancer.

One of the genes involved in telomere length was also associated with acne in a replication sample from the UK Acne Genetic study, also lead by King's scientists.

If further studies confirm the role of the mutation, Rodriguez says, researchers might be able to develop anticancer agents to target cells with ATRX mutations or ALT to limit telomere length.

Study results showed that chicks produced by older mothers and fathers had significantly greater telomere loss than chicks produced by younger parents, but the loss appeared to occur during nestling growth, rather than during the pre-natal period.

James Christiansen, professor of biology at Drake University in DesMoines, is studying how telomeres, the simple, non-genetic DNAsequences that sheathe the ends of chromosomes, function in reptiles.Each time a healthy human cell divides, it loses a little bit of thetelomere, until the strands are too short to protect the chromosomes.At that point the DNA in a cell begins to break down, which triggerssenescence and death.

Previous studies have shown that white blood cell telomere length can be predictive of biological aging and is linked with telomere length in other cells in the body.

Mice in which telomeres have been lengthened by gene therapy tended to live longer in some studies than mice that didn't get the treatment.

The study, published in Frontiers of Molecular Neuroscience, assessed the length of telomeres from 61 ADHD children (age 6 to 16) and their parents.