Sentences with phrase «studying cell abnormalities»

Backman has been studying cell abnormalities at the nanoscale in many different types of cancers, using an optical technique he pioneered called partial wave spectroscopic (PWS) microscopy.

Not exact matches

In a study, his team found that female incest survivors had abnormalities in the ratios of immune cells, compared with untraumatised women, exposing them to autoimmune diseases.

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

«Most previous research into ways of delaying the onset of HD symptoms have focused on studying the mutant protein in cells or in animal models, but the relevance of abnormalities in those systems to what actually happens in patients remains a huge assumption,» says James Gusella, PhD, director of the Center for Human Genetic Research (CHGR) at Massachusetts General Hospital (MGH), corresponding author of the Cell paper.

Raquel Oliveira, first author of this study, explains: «Many cancer cells have these type of chromosomal abnormalities and we now show that this can bring additional problems every time a cell divides.»

A recent generation of studies of postmortem brain tissue from people with schizophrenia, particularly from the laboratory of Professor David Lewis and his colleagues at the University of Pittsburgh, have shed light on schizophrenia - related abnormalities in the interplay of the main excitatory neurons, pyramidal neurons, and a specific class of inhibitory nerve cells, called chandelier cells, in the prefrontal cortex.

As before, abnormalities of islet morphology and β cells loss were studied by staining α -, β -, and δ - cells using anti-glucagon, anti-insulin, and anti-somatostatin antibodies, respectively (Fig. 7 C).

«Studies of fetuses and babies with the telltale small brains and heads of microcephaly in Zika - affected areas have found abnormalities in the cortex, and Zika virus has been found in the fetal tissue,» says Guo - li Ming, M.D., Ph.D., a professor of neurology, neuroscience, and psychiatry and behavioral science at Johns Hopkins» Institute for Cell Engineering.

(14,15)-RRB- have found age - related satellite cell attrition consistent with the senescence of a subset thereof; moreover, one such study (15) reported that decreases in the number and quality of satellite cells with aging are reliably associated with elevated expression of p16Ink4a (contrary to (14)-RRB-, and with secretory and proteomic abnormalities consistent with a rising burden of senescent cells.

Team Identifies Genetic Abnormalities in Stem Cell Lines — The study, from the Loring lab, suggests the need for frequent genomic monitoring of stem cells to assure their stability and clinical safety.

In previous studies, TERT - / - mice have been generated on either a C57BL / 6J or a 129 / C57BL / 6J mixed genetic background strain, both of which have «very heterogeneous and unusually long telomeres,» again raising the possibility that any developmental abnormalities might be due to subpopulations of stem cells with critically - short telomeres.

«Given these chromosomal abnormalities, I'd also worry about effects on sperm and egg cells,» says Dr. Solomon, who was not involved in the study.