Sentences with phrase «studying cell adhesion»

To better imitate cells» real environment in human body, researchers evenly mixed weak (rupture force of 12 pico - Newtons) and strong (rupture force of 54 pico - Newtons) tension gauge tethers and studied cell adhesion in the multiplex scenario.

Not exact matches

A 2012 study found that consuming maltodextrin increased bacterial adhesion to human intestinal epithelial cells and enhanced E. coli adhesion, which is associated with autoimmune disorders and dybiosis in your gut.

The results show that distinct genetic profiles underlie specific memory processes: The study reports, for example, associations between a transporter protein set and the process of learning as well as between a cell adhesion set and the process of memory storage.

In a new study, NAIST scientists, in collaboration with researchers at the Osaka National Hospital and University of Tokyo, report that the L1 Cell Adhesion Molecule (L1 - CAM) is crucial for directed axon migration.

The groundbreaking study identified a protein, known as cadherin - 22, as a potential factor in cancer metastasis, or spread, and showed that hindering it decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.

Their studies indicate that the two conditions common in sickle cell disease, dramatically increase red blood cells» adhesion to the lining of blood vessels walls and the debilitating pain crises that can result.

The study also points to a potentially new therapeutic target, the self - adhesion molecule P - selectin, which the researchers found played a central role in increased red blood cell adhesion.

«In our prior studies, tension gauge tethers with different tension tolerances were individually presented to cells, and we found the universal threshold force for integrin - mediated cell adhesion is around 40 pico - Newtons,» Roein - Peikar said.

The resulting endothelial cell lines described in this study retain their phenotype after repeated passage, require minimal nutritional support and, importantly, may be useful for identifying factors that regulate endothelial cell proliferation and tumor cell adhesion in different anatomical regions.

Pilot studies using a variety of strategies suggested that this goal could be best achieved by stimulating primary organ cell cultures with TNF - α (10 ng / ml) and targeting cells expressing the endothelial cell adhesion molecules E-selectin and VCAM - 1 through a FACS - driven strategy.

A study has shown that the immunosuppressive effect of MSCs is mediated by the secretion of galectin - 3, a protein known to modulate T cell proliferation, gene expression, cell adhesion and migration 44.

«Nanostructured materials are ideally suited to study the impact that spatial properties at the single molecule level have on cell adhesion.»

Recent studies reported that gestational nicotine exposure modulates the cell - adhesion and cell - death / survival systems in the brains of adolescent rats and may lead to numerous behavioral and physiological deficits [41], [42].

Another interesting local network structure is centered around CLU, a gene shown to be involved in AD based on genome - wide association studies, with genes in the integrin family, involved in cell adhesion, clustered around CLU.

Specific mechanistic studies include an interrogation of the adhesion dynamics controlled by the tetraspanin CD151 and affiliated adhesion receptors (Integrins and IgG cell adhesion receptors).

Other studies have shown that a family of proteins called 14 -3-3 are involved in learning along with interesting cell adhesion molecules of the integrin family and the immunoglobulin superfamily.

Genome - wide association studies have identified associations between body mass index and two loci near cell adhesion molecule 1 (CADM1) and cell adhesion molecule 2 (CADM2), which encode membrane proteins that mediate synaptic assembly.

Recently, a large - scale microarray study characterized gene expression differences between current, former, and never smokers [5], and identified specific genes related to xenobiotic functions, anti-oxidation, cell adhesion and electron transport to be more highly expressed in current smokers relative to never smokers.

By utilizing the tools of cell and molecular biology, he studies the mechanisms by which chemical (for example, specific cell adhesion molecules) or mechanical signals (for example, cyclic strain) are sensed by cells and alter their proliferation and specialization to either promote tissue growth or destruction.

Studies cover a breadth of topics ranging from single molecules (molecular motors, DNA - protein interactions, membrane proteins) to cellular functions (cell adhesion, cell division, cell motility, intracellular transport) and the collective behaviour of cells in tissues and organisms (wound healing, morphogenesis).

In a cell - culture study, polyunsaturated fats did not alter TNF - α — mediated up - regulation of the adhesion molecules ICAM - 1, VCAM - 1, and E-selectin (34).

A recent in vitro study showed that incorporating a greater extent (2-fold) of TFA in the phospholipid fraction of endothelial cells significantly increased the expression of endothelial adhesion molecules, including ICAM - 1 (25).

Scientific studies have documented that the deadly powder on gloves increases wound infection, causes adhesions that can compress the bowels, and spreads tumor cells throughout the cavity.