Sentences with phrase «studying host factors»

Not exact matches

Studies comparing human milk from preterm mothers with that from term mothers suggest that these immunologic benefits may be even greater for preterm infants because secretory immunoglobulin A (IgA), lysozyme, lactoferrin, and interferon are found in greater concentrations in preterm human milk compared with term milk.2 — 4 Very low birth weight (VLBW) infants do not benefit from the transplacental transfer of maternal immunoglobulins that occurs primarily after 34 weeks of gestation.5 These infants are exposed to abundant pathogenic organisms during neonatal intensive care unit (NICU) hospitalization and may benefit from the host defense factors present in preterm human milk.6 — 9

«There is a host of factors that appear to be driving mortality, and the likelihood of those factors occurring is increasing,» added McDowell, who headed the team of scientists from more than two dozen institutions across the globe who were involved in the study.

As well as studying the effects of genetic variations in the virus, scientists are also starting to learn what factors in the host might influence the spread of HIV.

In future studies, the team plans to use the model to better understand how microbes, host factors and inflammatory markers interact to produce the hallmarks of inflammatory disease in the intestine.

«Our study shows that we can use this new CRISPR / Cas9 gene - editing technology to render mosquitoes malaria - resistant by removing a so - called host factor gene,» says study senior author George Dimopoulos, PhD, professor in the Bloomberg School's Department of Molecular Microbiology and Immunology.

In addition, he and his team are using their CRISPR / Cas9 DNA - editing platform to study the effects of deleting other potential malaria host - factor genes and to learn more about the roles of these host factors in mosquitoes.

We used a mathematical model of within - host virus evolution to study factors that could increase and decrease the probability of the remaining substitutions evolving after the virus has infected a mammalian host.

Although this study represents only a single case, it provides unprecedented detail on the host response to Ebola virus disease and may inform the development of therapeutics designed to boost or accelerate host factors that most effectively counter the virus and promote healing.

Knut Madslien has monitored the spread pattern of deer keds in Fennoscandia, produced a description of pathological hair loss in moose in Southeast Norway in 2006/7 and studied environmental factors which can be favourable for the parasite and possible pathogens in the deer ked and its host.

«Nomograms offer the ability to personalize survival estimates for patients based upon a host of factors that are clinically relevant when we meet patients,» stated Carole Fakhry, MD, the study's lead author and an associate professor in the Department of Otolaryngology Head and Neck Surgery at John Hopkins University.

«This study identifies PHB as the first host factor that is specifically involved in EV71 infection of the CNS,» the authors further explain.

Their findings — that nanotubes and vesicles are an important part of the communications process — show that the extracellular vesicles contribute to the complexity of African trypanosomiasis through the transfer of virulence factors between parasites and inadvertent interaction with host cells, which has a profound effect on disease, the study notes.

In many studies of human subjects the question of interest centers on whether a biological factor (disease state, treatment, host genotype etc.) results in a measurable difference on a gut bacterial community against the background of the naturally occurring differences among humans.

During that period she was involved in both HIV and HCV viral infections, studying the role of plasma drugs» concentrations, and host and viral genetic factors on the outcome of the standard HCV therapy.

Additional in vitro and in vivo studies are needed to determine the cause of the specificity of JAK2V617F for myeloid diseases, as second mutations, host modifiers, differential cytokine receptor expression, and other factors may influence the ultimate phenotype of hematopoietic progenitors that acquire the JAK2V617F mutation.

Goyal RK, Lin Y, Schultz KR, Ferrell RE, Kim Y, Fairfull L, Livote E, Yanik G, Atlas M. Tumor necrosis factor - alpha gene polymorphisms are associated with severity of acute graft - versus - host disease following matched unrelated donor bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium study.

Variation in microbiome structure due to diet, health status, age, and other factors is being studied extensively, but the effect of host genotype is less well described.

Several studies have shown that low serum magnesium is an independent risk factor for migraine headaches, and that magnesium can be used therapeutically to both prevent and treat migraines, as well as a host of other disorders characterized by spasm.

includes: Physical factors pushing people out of Niger Human factors pushing people out of Niger costs and benefits of migration for host country - economic + / — social + / — political + / - has several case studies from recent news article

One study that controlled for these factors found that the charters touted as successful — KIPP, Achievement First and Uncommon Schools — spend between 20 - 30 percent more than comparable public schools in their host districts.

During his PhD under the supervision of Drs. Luis Enjuanes and Fernando Almazan at the National Centre of Biotecnology (Madrid, Spain), he studied the mechanism of replication and transcription of coronavirus and the role of host factors that modulate these processes.

We have turned our attention to studying possible host factors that contribute to the risk of bone sarcoma development.

The purpose of our study was to determine if specific host factors, such as age at diagnosis, obesity, and hormone status, influence the prognosis of canine mammary gland carcinomas and to confirm if previously reported risk factors (ie, histologic subtype, tumor size, and World Health Organization [WHO] stage) were important in a large series of affected dogs.

His technical publications included a study of host factors in pituitary chromophobe adenoma, in Metabolism, and an essay on medical obfuscation in the New England Journal of Medicine.

Indeed, they go on for an additional two paragraphs citing other factors which influenced the determination of the Anthro contribution as portrayed in fig 10.5, and still further discussion calling on a host of further studies relating to the role of Internal variability (which unlike forcings, which will scale alike, thus preserving relative contribution, may have been an issue).

The process of non-voluntary immigration, transitioning and acculturating to a new country may have a negative impact on the mental health of immigrants.1 — 3 Postmigration factors (eg, stress, lack of social capital, social isolation and loss of social network) as well as acculturation problems and experiences of discrimination in the host country affect the mental health of the parents and the children.4 5 Moreover, immigrant parents face challenges concerning their role and responsibilities as parents while adjusting to the host country, all of which tend to create stress in parenting.1 3 6 The mental health problems of parents have been reported to be a risk factor for children's behavioural problems and may negatively affect the parent — child attachment and their relationship.7 8 Studies have also shown that parents with mental health problems have a low perceived sense of competence in parenting and may lack the ability to employ positive parenting practises.9 10

This webinar is hosted by Center for the Study of Social Policy (CSSP) and the National Alliance of Children's Trust and Prevention Funds and will briefly review how Be Strong Families developed and spread Parent Cafés before diving into the Vitality Domains and Cafés and crosswalk with the Strengthening Families Protective Factors.

This study assumes that socio - emotional development of infants would be equally affected by different factors among which is type of feeding in addition to other factors such as micronutrient adequacy, demographic factors (as maternal education and socioeconomic status), and host factors (as child order of birth).

But the decision whether to buy or build a business in the United States is also governed by a host of factors — geographic, demographic, financial and industrial — that need to be studied by foreign investors before making a commitment.