Sentences with phrase «studying human chromosomes»

Two decades later a French researcher studying human chromosomes under a microscope identified CNV as the cause of Down syndrome: sufferers inherit an extra copy of chromosome 21.

Not exact matches

Some six decades ago, it had been used in the study of human chromosomes: The chemical, which could stop mitosis in its tracks, made it easier to spy the dividing chromosomal strands in metaphase, where they could be clearly viewed under a light microscope.

This theological perspective is much broader and more sweeping in scope than what appears in the X chromosome study which does not ask about the total orientation of the human self.

The researchers behind the new study say that the fact that this mechanism is highly similar in human cells and yeast cells suggests that it plays a key role in ensuring proper chromosome distribution following each cell division.

«They should have been able to use the Y chromosome tree to see that inconsistency,» says Peter Underhill, who studies the human Y chromosome at Stanford University in California.

In this study, researchers took cells from patients with blood cancer MDS and turned them into stem cells to study the deletions of human chromosome 7 often associated with this disease.

The study involved Y chromosomes obtained through the Human Genome Diversity Project, and from other sources.

The team hopes their work will lead to further research on Y chromosomes as vehicles for studying human history — and tracing male lineages back to the common «Adam» ancestors.

Jeffrey Kidd, Ph.D., an Assistant Professor of Human Genetics and Computational Medicine & Bioinformatics who worked on the new study, notes that only recently has it become possible to sequence Y chromosomes, because of technical limitations of previous approaches.

«The X is the most famous, most intensely studied chromosome in all of human genetics.

The evolution of human populations has long been studied with unique sequences from the nonrecombining, male - specific Y chromosome (see the Perspective by Cann).

A drug that stops the HIV virus from stitching itself into human chromosomes is found to fight AIDS in an animal study.

It also undergoes cell division by first creating copies of chromosomes like most human cells and has a very fast replication cycle, all of which facilitated the study.

James Christiansen, professor of biology at Drake University in DesMoines, is studying how telomeres, the simple, non-genetic DNAsequences that sheathe the ends of chromosomes, function in reptiles.Each time a healthy human cell divides, it loses a little bit of thetelomere, until the strands are too short to protect the chromosomes.At that point the DNA in a cell begins to break down, which triggerssenescence and death.

A well - studied example of a human gene is the ACE gene on chromosome 17, which seems to predict physical performance.

In this study, the last three amino acids of the Pten protein, which are often missing in human cancers, were found to be critical for forming an intact mitotic spindle, a structure required for accurate chromosome segregation.

Ann Chandley of the Medical Research Council's Human Genetics Unit in Edinburgh and Tim Hargreaves of the Western General Hospital in Edinburgh have recently launched a worldwide study to look for gene mutations on the Y chromosomes of ICSI fathers and sons.

Early in her studies, while still a postdoctoral fellow in the laboratory of Nobel laureate Harold Varmus at the University of California - San Francisco, she was one of the first to isolate the telomeres of human chromosomes.

PARENTAL GUIDANCE RULES: Maternally methylated (red dots) and paternally methylated (blue dots) regions across the human autosomal chromosomes, based on studies of uniparental disomy samples

ONE - PARENT SAMPLE SET PARENTAL GUIDANCE RULES: Maternally methylated (red dots) and paternally methylated (blue dots) regions across the human autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are exprehuman autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expreHuman METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expressed.

Studies show that the San carry some of the most divergent (oldest) Y - chromosome haplogroups, specific sub-groups of A and B, the two earliest branches on the human Y - chromosome tree, suggesting they may be descendents of a population ancestral to all modern humans.

The evidence emerged from a linkage study of Icelandic families that showed that schizophrenia correlated with an area on the eighth of the 23 pairs of human chromosomes.

A new study, looking at the sex - specifically inherited X chromosome of prehistoric human remains, shows that hardly any women took part in the extensive migration from the Pontic - Caspian Steppe approximately 5,000 years ago.

New study establishes platform for investigating chromosome regulation during early human development.

The gene was mapped to a small region on chromosome 18, which previous studies have suggested may play a role in blood pressure regulation in humans, mice and rats.

In the present study, we used a combination of BAC clone contig construction, polymorphism analysis of DNA from congenic strains, and sequence mining of the human orthologous region to generate an integrated map of the Idd10 region on mouse chromosome 3.

The properties of the human Y chromosome - namely, male specificity, haploidy and escape from crossing over - make it an unusual component of the genome, and have led to its genetic variation becoming a key part of studies of human evolution, population history, genealogy, forensics and male medical genetics.

Studies of Y - chromosome diversity in other great apes are relatively undeveloped compared to those in humans, but have nevertheless provided insights into speciation, dispersal, and mating patterns.

«Telomeres, the protein caps on the ends of human chromosomes, are markers of aging and overall health,» said study leader Dr. Naruhisa Yamaki, a clinical fellow at the Kobe University Graduate School of Medicine in Japan.

Orientin and vicenin are two water - soluble flavonoids that have been of particular interest in basil, and in studies on human white blood cells; these components of basil protect cell structures as well as chromosomes from radiation and oxygen - based damage.

This type of study tries to locate a specific gene on a chromosome in the human body.