Thanks to our new tools for
studying human muscle cellular clocks in vitro, we now have the possibility to investigate this hypothesis in our next study.»
Not exact matches
Interestingly — and somewhat frustratingly — a similar
study in the journal Medicine and Science in Sports and Exercise found that while pre-workout whey does increase energy expenditure it also decreases levels of the
muscle building
human growth hormone (HGH) and testosterone.
The cognitive differences between
humans and our closest living cousins, the chimpanzees, are staggeringly obvious and a new
study suggests that
human muscle may be just as unique.
The result was the largest deletion ever observed in the dystrophin gene using CRISPR / Cas9, and the
study was the first to create corrected
human iPS cells that could directly restore functional
muscle tissue affected by Duchenne.
In their
study, Stephanie Cherqui, PhD, associate professor in the UC San Diego School of Medicine Department of Pediatrics, and colleagues used a transgenic mouse model that expresses two mutant
human FXN transgenes, and exhibits the resulting progressive neurological degeneration and
muscle weakness.
«It's taken years of trial and error, making educated guesses and taking baby steps to finally produce functioning
human muscle from pluripotent stem cells,» said Lingjun Rao, a postdoctoral researcher in Bursac's laboratory and first author of the
study.
Marathon running might be in some people's genes, according to a new
study, which shows that a genetic mutation that boosts
muscle endurance has spread widely in some
human populations.
Studies in
humans have shown that age - related
muscle loss can be partially staved off with exercise, especially weight training.
«It's anybody's guess how they are doing it,» says Reggie Edgerton, a physiologist at the University of California, Los Angeles, who has
studied muscle atrophy in
humans during space flight.
The length of a
human muscle changes by only about 20 %, says neurobiologist William Kristan of the University of California, San Diego, who was not involved in the
study, since it is constrained by a skeleton.
«This configuration moved the hip
muscles away from the hip joints and gave them more leverage in walking — perhaps more of an advantage than
humans have today,»
study co-author Jeremy DeSilva, an anthropologist at Dartmouth University, said in the statement.
In a series of
studies this year, molecular geneticists at the University of Pittsburgh School of Medicine used a harmless virus to ferry new genes through the bloodstream, across blood vessel walls, and into almost every
muscle cell in the bodies of hamsters bred to have
human genetic diseases.
The use of
muscle tissue in post-mortem
studies is a novel approach which presents several advantages: first,
muscle tissue is the most abundant tissue of the
human body and can therefore be sampled easily.
By
studying the
muscles of bonobos (which indicates how they physically function), the team was able to discover that they are more closely related to
human anatomy than common chimpanzees, in the sense that their
muscles have changed less than they have in common chimpanzees.
«This is the first
study to demonstrate that functional
muscle cells can be created in a laboratory and restore dystrophin in animal models of Duchenne using the
human development process as a guide.»
The scientists, who are faculty in the university's School of Medicine, are
studying how oxidative stress in cells impacts sarcopenia — a loss of
muscle mass and strength that occurs in all
humans as they age.
A new
study from Karolinska Institutet in Sweden shows that long - term endurance training in a stable way alters the epigenetic pattern in the
human skeletal
muscle.
Although the current
study demonstrates that loss of IL - 15Rα promotes this phenotype, future
studies are needed to determine the roles of specific IL - 15Rα isoforms in
muscle, as well as the associations of additional IL15RA polymorphisms in
muscle phenotypes in
humans.
The
study is entitled, «Testing for Recombinant
Human Erythropoietin in Urine: Problems Associated with Current Anti-Doping Testing,» and was conducted by Carsten Lundby, Niels J. Achman - Andersen, Jonas J. Thomsen, Anne M. Norgaard and Paul Robach, all of the Copenhagen
Muscle Research Center, Copenhagen, Denmark.
This is the first
study to show that the repeat genome can be effectively targeted using CRISPR technology, the first use of CRISPR inhibition for a
human disease, and the first use of CRISPR technology in primary
human muscle cells.
Most of the
study's experiments were done in the roundworm C. elegans, which have an SMN gene and motor neurons — those that connect to
muscle — that are very similar to
humans, making them valuable models in which to
study this disease.
Today, Yin is a regeneration biologist and assistant professor at MDI Biological Laboratory in Bar Harbor, leading a team
studying a drug that could nudge the
human body into regenerating heart
muscle.
Human satellite cell cultures display numerous features of mature skeletal
muscles (1) and have been used for
studies of
muscle metabolism in cultures established from patients with type 2 diabetes and healthy control subjects (1 — 5,8,9,21,22).
The animal model used for this
study is a nematode worm genetically engineered to produce
human alphasynuclein in its
muscles.
Students receive training with a «systems» biology approach through courses, bench work, lab discussions and publications spanning a broad range of
muscle - biology questions using
studies at the level of single cells, tissues, animals and
humans.
In a
study using
human muscle tissue, scientists in Children's Stem Cell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into
muscle, bone and cartilage cells.
The animal model used for this
study, C. elegans, is a nematode worm genetically engineered to produce
human α - synuclein in its
muscles.
Human skeletal
muscles have an epigenetic memory of earlier encounters with growth, according to a Keele University - led
study.
Two
studies demonstrate the first direct, chemical reprogramming of mouse and
human skin cells into heart
muscle and neural cells.
Jeyaraj and her colleagues
studied smooth
muscle cells derived from tiny blood vessels harvested from
human skin biopsies and similar cells from mouse tail arteries.
The synapse between a neuron and a
muscle — the neuromuscular junction — of a fruit fly larva turns out to be a good model for
studying how the nervous system works in general, which can be applied to other organisms, including
humans.
«The range of applications of these low cost and light weight artificial
muscles is really wide and involves different fields such as robotics, prosthetics, orthotics, and
human assistive devices,» says Caterina Lamuta, an author of the
study.
Rather than asking you diagnostic questions, and relying on your conscious mind and intellect for answers, kinesiologists look to your
muscles and movement for answers about what's going on in your body (
human kinetics, is the scientific
study of
human movement).
Human studies indicate that people with higher serum D3 levels have a decreased risk for falls and
muscle weakness as well as less insulin resistance and diabetes.
The
study was performed in 2002 and found that «plasma amino acid elevation induces skeletal
muscle insulin resistance in
humans» (18).
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The IF
studies performed on
humans in relation to body composition,
muscle mass and athletic performance indicate that intermittent fasting produces the best results when done in conjunction with strength training.
Probably the most amount of interest in the idea that
human growth hormone injections could help people to drop pounds and to gain
muscle was verified by a
study published in the New England Journal of Medicine.
HGH (
human growth hormone) has become a hot topic in the bodybuilding community ever since the «New England Journal of Medicine» published a
study stating the various
muscle building advantages of it.
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human study 12.01.2014 Grape Seed Extract speeds up damaged
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Because while no
human studies have confirmed this effect, numerous animal
studies have demonstrated it reliably, showing overall
muscle size increases in the order of 300 % (which is HUGE).
The landmark 2013
study by Dr. Sinclair demonstrated that supplementation with NMN increased levels of NAD + and reversed age related degeneration in mice, giving older mice the
muscle capacity, endurance and metabolism of much younger mice — the «equivalent of a
human 60 year old becoming more like a 20 year old» (24).
Study 3: Heres» an interesting new study on the effects of keto diet on human mus
Study 3: Heres» an interesting new
study on the effects of keto diet on human mus
study on the effects of keto diet on
human muscles.
Some animal
studies have shown that vanadium, like insulin, can promote amino acid transport into the cells, but various
studies in
humans have not confirmed any increase of the
muscle mass or athletic endurance after taking vanadium supplements [6].
In the short term, a workout consisting of four 30 - second all - out cycling sprints activated mitochondrial biogenesis in the skeletal
muscle of
human subjects in one
study.
Fr example, one
study done over a ten year period in the 1990s showed that men who took
human growth hormone showed increased
muscle mass as compared with men who did not take
human growth hormone.
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EMG (Electromyography)
studies demonstrate that the
human being can actively produce more force when putting intention into what
muscles are contracting.
Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose - response
study
While the exact mechanism of the effect on the ubiquitin pathway is not currently known,
studies in both animal models and
humans have shown the same effect, reduced protein breakdown, which helps maintain more
muscle mass.