Sentences with phrase «studying lab dishes»

Not exact matches

WASHINGTON — Tiny orbs of brain cells swirling in lab dishes may offer scientists a better way to study the complexities of the human brain.

So far, researchers have mostly turned on genes with CRISPRa in cells growing in lab dishes, says Charles Gersbach, a biomedical engineer at Duke University not involved in the new study.

That allowed tumor cells to survive gemcitabine treatment in lab dishes and mouse studies, Leore Geller of the Weizmann Institute of Science in Rehovot, Israel, and colleagues discovered.

The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.

Studies of individual neurons in dishes of cultured neurons and in brain slices by co-first author Robert E. Stanley, a graduate student in the lab, revealed that neurons in the mutant mice had decreased numbers of dendritic spines, an important part of the synapses that neurons use to communicate with one another.

So instead of studying the whole animals, he began isolating single nerve cells from the mole rats and investigating them in lab dishes to track the molecular basis of the rodent's pain insensitivity.

Their study, published in the ACS journal Chemical Research in Toxicology, found that triclosan, as well as another commercial substance called octylphenol, promoted the growth of human breast cancer cells in lab dishes and breast cancer tumors in mice.

In addition, MAO is known to be associated with Alzheimer's, but studies establishing this relationship were only conducted in lab dishes and test tubes.

To precisely map how glucose and lactate move around in the eye, Hurley and colleagues grew human RPE in a lab dish and studied its biochemistry along with that of isolated mouse retinas.

Previous evidence for a breast cancer link has been mixed — one study found increased risk in women exposed before age 14, whereas others found no association — but in a lab dish, DDT has been shown to activate the HER2 gene in human breast cells, which is expressed in some breast cancers.

In a study published today (Aug. 4, 2016) in Cell Reports, senior author Chapman, first author Bomba - Warczak and colleagues present clear evidence that toxin is moving between neurons in a lab dish.

But making chimeras with human organs whose development can be studied is more likely to succeed than the technique researchers have been trying for years: coaxing stem cells growing in lab dishes to become three - dimensional, functional tissues and organs.

Zhang has been using a different approach — studying diseased human cells in lab dishes.

Once they knew that AXL was present in the right locations to cause the damage that had been observed in babies, two other lab members, Elizabeth Di Lullo, PhD, and Marina Bershteyn, PhD, looked to see if the «mini-brains» — cerebral organoids that scientists grow in a dish to study neurological diseases — were also programmed to express AXL and found that they were.

The cell types involved in diabetes — the beta and immune cells — are being studied in the culture dish, as well as transplanted into lab animals.

In a study published earlier this year, the same Belmonte and Gage lab team demonstrated that a few ES cells in a culture dish tended to lose stemness and evolve into muscle cell precursors, most likely goaded by a muscle differentiation factor known as BMP.

More than 6,000 papers have been published on these so - called beta glucans, but almost all the data about preventing infections had come from petri dish or lab animal studies, until a few years ago when a series of experiments on athletes showed beneficial effects — but that was in marathon runners.

The bacteria that causes syphilis, Treponema pallidum, is difficult to study in the lab, as it can't be grown in a test tube or Petri dish.