Sentences with phrase «studying outcomes of therapy»

Researchers studying outcomes of therapy are beginning to focus attention on this approach as a family therapy.

Not exact matches

REDUCE - IT is the first multinational cardiovascular outcomes study evaluating the effect of prescription pure EPA therapy, or any triglyceride - lowering therapy, as an add - on to statins in patients with high cardiovascular risk who, despite stable statin therapy, have elevated triglyceride levels (150 - 499 mg / dL).

Additionally, by sticking to a routine of frequent and regular follow - up visits for the purpose of an outcome study, you can be confident that any possible problem your premature baby may encounter later on in life will be spotted immediately, and proper therapy can begin right away.

A 2011 study on the outcome of cranial molding helmet therapy at various ages determined that the best outcomes were achieved when children began helmet therapy between the ages of 5 and 6 months.

People with chronic opioid use disorders are more likely to relapse and do so sooner if they are treated in a compulsory drug detention centre rather than a voluntary drug treatment centre using methadone maintenance therapy, according to the first study comparing the outcome of both approaches published in The Lancet Global Health.

«Our results demonstrate that if we find the right molecular context, more appropriate therapies can be chosen that improve outcomes,» says John Carpten, Ph.D., TGen deputy director of basic science and director of TGen's Integrated Cancer Genomics Division, and the study's senior author.

Researchers at the Veterans Health Administration conducted a systematic review of 67 published studies to determine the effectiveness of strategies to reduce or discontinue long - term opioid therapy prescribed for chronic pain and the effect of dose reduction or discontinuation on important patient outcomes.

Placebos are used to help accurately measure clinical responses / outcomes when studying the effects of medications, therapies, and other treatments.

The study, entitled COMET (Comparison of Operative to Medical Endocrine Therapy) for low - risk ductal carcinoma in situ, received funding through a $ 13.4 million, five - year award from the Patient - Centered Outcomes Research Institute (PCORI), an independent, nonprofit organization authorized by Congress in 2010 to support research that enlightens health care decisions.

The study, «Acceptance and Commitment Therapy to Manage Pain and Opioid Use after Major Surgery: Preliminary Outcomes from the Toronto General Hospital Transitional Pain Service,» is published in the Canadian Journal of Pain, by first author Muhammad Azam, Ph.D. candidate at York University and senior authors Dr. Joel Katz, Affiliate Scientist, Toronto General Hospital Research Institute (TGHRI) and Dr. Hance Clarke, Director of the Transitional Pain Service at TGH, UHN and Clinical Researcher, TGHRI.

The data safety monitoring board of the trial, as mandated by the study protocol, continues to monitor outcomes in patients with a Recurrence Score of 11 to 25 randomized to chemo - endocrine therapy or endocrine therapy alone.

Led by Joke Bradt, PhD, associate professor in Drexel University's College of Nursing and Health Professions, a team looked into studies that examined the impact of music therapy (a personalized music experience offered by trained music therapists) and music medicine (listening to pre-recorded music provided by a doctor or nurse) on psychological and physical outcomes in people with cancer.

The researchers suggest that their study demonstrates the potential of these non-toxic therapies to contribute to current cancer treatment regimens and significantly improve the outcome of patients with advanced metastatic cancer.

«Preclinical studies suggested that this combination therapy would have better outcomes than those elicited by their individual or sequential administration,» said Hodi, who is also director of the Melanoma Center at the Dana - Farber Cancer Institute.

«Defining the biology of naturally occurring protective mutations is quite important, because they define desired outcomes for potentially new therapies,» explained the study's co-author Judy H. Cho, MD, Director of the Sanford Grossman Center for Integrative Studies in Crohn's disease, and the Charles F. Bronfman Institute for Personalized Medicine at the Icahn School of Medicine at Mount Sinai.

«Triple - negative breast cancers tend to be more aggressive compared to other types of breast cancers, and being able to predict response to therapy could greatly impact treatment decisions and patient outcomes,» says study author Shaveta Vinayak, MD, oncologist at UH Case Medical Center and Assistant Professor at Case Western Reserve University School of Medicine.

«This study suggests that targeting p27, GATA3 and POU4F3 may enhance the outcome of gene therapy and other approaches that aim to restart ATOH1 expression,» Zuo said.

When outcomes from these two groups were added together, the absence of any benefit from drug therapy in patients with an unwitnessed arrest may have muted the significant benefit seen in those with a witnessed cardiac arrest, resulting in the marginal overall outcome of the study.»

Kessler will conduct a study of a combination therapy using dalfampridine — a drug recently approved to improve walking in patients with multiple sclerosis — with a standardized program of locomotor training, a rehabilitative intervention that has improved walking and other functional outcomes in persons with spinal cord injuries.

The traditional approach, in which researchers studied the clinical outcomes of an intervention without assessing whether the intervention altered a well - defined target, established current, well - accepted treatments such as exposure therapy and dialectical behavior therapy.

Combined with our expertise in spinal cord injury, gait analysis, locomotor training, robotic technology, and therapy training requirements, we are well positioned to contribute to outcomes of the WISE study.»

The technology successfully tracked in real - time how the diversity of tumor cell populations were changing in response to particular therapies for all of the patients studied, and was highly predictive of treatment effectiveness and patient outcomes.

Failure to respond to this therapy is in fact a major unmet clinical need of solid tumors and this study may help stratify patients and inform novel approaches to improve clinical outcomes.

LA JOLLA — Scientists at the Salk Institute for Biological Studies have identified a key genetic switch linked to the development, progression and outcome of cancer, a finding that may lead to new targets for cancer therapies.

[79] A total of 86 patients with advanced mucosal melanoma were included in the nivolumab monotherapy analysis, and 35 patients with mucosal melanoma were included in the combination therapy analysis; in addition, outcomes in these patients were compared with outcomes in patients with cutaneous melanoma who were treated in these clinical studies.

During that period she was involved in both HIV and HCV viral infections, studying the role of plasma drugs» concentrations, and host and viral genetic factors on the outcome of the standard HCV therapy.

«It is our hope that emerging technologies and future studies will expand on our work, and ultimately lead to safe, targeted, and cost - effective therapies that markedly improve visual outcomes and quality of life for patients suffering from these debilitating eye diseases.»

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

Armed with this knowledge, and the results of an initial feasibility study, the Dream Team will conduct a clinical trial to evaluate if personalized therapy, based on the genetic profile of each individual patient's cancer, improves outcomes.

The study, published in November 2016 in The Lancet Oncology and presented with updated outcomes at the October 2017 World Conference on Lung Cancer in Yokohama, Japan, reported that 57 percent of patients receiving the combination therapy responded to treatment, whereas only 31 percent responded to chemotherapy alone.

A major new paper from Sarah Tabrizi and colleagues, reporting the final outcomes of the TRACK - HD study, provides information that will help us better design trials of new therapies in HD as well as understand how the disease progresses.

«Much to our surprise, the trial showed that patients receiving standard therapy compared to those receiving cetuximab with standard therapy had no difference in outcomes,» said study author Dr. Steven Alberts, a professor of oncology at the Mayo Clinic College of Medicine in Rochester, Minn. «It also indicates that disease in earlier stages may be different than diseases in later stages.»

Although it is often suggested that children with epilepsy who are benefiting from ketogenic dietary therapy continue this for at least two years, duration of treatment could be shorter in patients with infantile spasms who become seizure - free; one study reported no adverse effect on seizure outcomes and less risk of growth disturbances when treatment was tapered down after 8 months (15).

One study has assessed long term outcomes of 68 LGS patients over a mean follow up period of 19 years: of the 19 who tried diet therapy, 5 maintained seizure freedom on the traditional ketogenic diet and one on MAD (13).

UACIM research activities contribute rigorous scientific studies on the integration of complementary therapies with conventional medicine, with a focus on educational research, corporate health improvement research, and methods to study clinical outcomes in integrative medicine.

Board Certification Domains (2015), the outcome of the 2014 Practice Analysis Study which measured and defined current music therapy practice, is now available.

CONTEXT Pramipexole and levodopa both ameliorate the motor symptoms of early Parkinson disease (PD), but no controlled studies have compared long - term outcomes after initiating dopaminergic therapy

Literature review and site interviews mark the launch of a study that will examine the outcomes of animal - assisted therapy on pediatric cancer patients and their families

Future study should assess the outcome and level of return to function of patients with cranial cruciate ligament insufficiency treated with rehabilitation therapy and a custom stifle orthotic.

Multi-site Research Study Will Examine the Outcomes of Animal - Assisted Therapy for Pediatric Cancer Patients and Their Families

PROFESSIONAL SUMMARY * 18 years of experience in data management * Leading data management staff in support of startup, conduct and close out including the largest cardiovascular outcomes trial in the industry * Managing several direct reports and leading large teams for both study project work in multiple therapy areas and initiatives for operational efficiency * Managing departmental resources, budgets and goals to ensure success * Providing expertise for global filings including preparatio...

Measurable outcome studies continue to have trouble collecting data to evidence positive behavior change as a result of therapy.

Summary: (To include comparison groups, outcomes, measures, notable limitations) This study compared the efficacy of a manualized cognitive behavior therapy that addresses both posttraumatic stress disorder (PTSD) and substance abuse (Seeking Safety (SS)-RRB- with a manualized cognitive behavior therapy that addresses only substance abuse (Relapse Prevention) and with standard community care for the treatment of comorbid posttraumatic stress disorder (PTSD) and substance use disorder.

As Weisz and colleagues34 have stated, the crucial question is whether community clinicians can actually benefitfrom the findings of outcome research, and an important task is to study theapplication of research therapy to community settings.

There is growing evidence for online mindfulness courses being as effective as other face - to - face interventions and online courses for stress even without a therapeutic alliance.37 — 40 Previously found Perceived Stress Scale (PSS) effect sizes are comparable to those found with face - to - face mindfulness and CBT interventions, including our previous research examining the course currently under investigation.40 — 42 One RCT found that an automated internet - based therapy including CBT and mindfulness actually had better outcomes for Irritable Bowel Syndrome (IBS) than the comparative online therapist - led intervention, suggesting that the effects of internet interventions can not be attributed to, and do not rely on, therapist interaction.43 Studies are finding that online mindfulness courses can be beneficial for depression in samples with IBS and epilepsy and anxiety symptoms in a non-clinical sample comparing a 3 - week mindfulness course with positive psychology interventions and treatment as usual (see Monshat38 for a review).

McRoberts et al (1998) conducted a meta - analysis of 23 outcome studies that directly compared the effectiveness of individual and group therapy formats when they were used within the same study.

He completed his predoctoral internship at the Center for Cognitive Therapy in Philadelphia, conducted the first comparative outcome study on what is now known as ACT as part of his dissertation under the supervision of ACT founder Steven Hayes, and has published both basic and applied research relating to rule - governance, experiential avoidance, and ACT for depression for more than twenty years.

The results of a major comparative outcome study have shown schema therapy to be highly effective with a large percentage of outpatients with Borderline Personality Disorder, with a low dropout rate.

We conducted a study to examine the relationship between parental bonding, schema domains / EMSs, and outcome in schema therapy of personality problems.

A series of small, mainly uncontrolled, studies have suggested that techniques adapted from cognitive — behavioural therapy (CBT) for depression can improve outcome in psychosis, but no large randomised controlled trial of intensive treatment for medication - resistant symptoms of psychosis has previously been published.