Sentences with phrase «studying patient biopsy»

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All female patients with a biopsy - proven diagnosis of melanoma between 1988 and 2012 were included in the study, while patients with a follow - up of less than two years were excluded.

Our current multi-centre pivotal study has shown that in many patients, by using a radiotracer with a novel receptor - based mechanism, the SN can be reliably identified and removed for biopsy without having to undertake more extensive surgery.

«This study demonstrates that targeted fusion - guided biopsy could significantly enhance our ability to identify patients with high - risk prostate cancers that need more aggressive treatment,» says lead author Mohummad Minhaj Siddiqui, MD, assistant professor of surgery at the University of Maryland School of Medicine and director of urologic robotic surgery at the University of Maryland Marlene and Stewart Greenebaum Cancer Center.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

In a new study, researchers are taking joint biopsy tissue from patients at the start of a new therapy and then six weeks later to see if they can find a predictor gene sequence that will clearly identify which patients respond to a particular therapy.

The study, published in Alimentary Pharmacology & Therapeutics, provides evidence that using the non-invasive technology as a first - line test can rule out the need for further liver tests, and could stop patients having unnecessary biopsies.

In this study, researchers analyzed prostate tissue biopsies from two cohorts of prostate cancer patients.

«We used biopsied tumor samples from DIPG patients to create models in the lab, which we studied and then used to test a novel, targeted approach to treating the tumor.

The test, which is described in a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN), may allow patients to avoid invasive kidney biopsies when their transplanted organ is not functioning properly.

«Our study shows that when the creatinine level is elevated in the blood of a kidney transplant recipient, use of our urine test would differentiate the common causes of kidney dysfunction that led to the elevation in creatinine, hence benefiting many patients by allowing them to avoid the need for an invasive needle biopsy,» said Dr. Muthukumar.

The researchers studied the adhesion mechanisms using detailed biochemical analyses and state - of - the - art genetic systems, combined with unique H. pylori clinical strains and biopsy - materials collected from individual patients and animals over a span of many years.

We found that performing MRI before biopsy and using that information to alter biopsy pathways would be a strategy that would add health benefits to the patient population in a cost effective manner,» said Vikas Gulani, MD, PhD, study advisor and associate professor of radiology, urology, and biomedical engineering at Case Western Reserve University School of Medicine, and member of both the Case Comprehensive Cancer Center and Case Center for Imaging Research.

In this study, researchers assessed the outcomes of 280 prostate cancer (Cap) patients, and reviewed the DNA «fingerprints» of each patient's tumor (using the patient's initial diagnostic core biopsy) to determine if gene copy number alterations (CNAs), or breaks in CFSs, were related to a less positive response to treatment.

The study examined more than 20 years» worth of clinical and laboratory data of more than 1,000 patients with biopsy - confirmed NAFLD.

The researchers also obtained liver biopsies from patients, which they studied using RNA sequencing.

The racially diverse study sample consisted of two groups: 89 patients diagnosed with low risk prostate cancer (clinical stage T1 - T2a, biopsy Gleason score 6 or less, and prostate specific antigen less than 10 ng / ml), who initially underwent AS, and 420 patients without cancer who had a negative prostate needle biopsy.

In a field where time and accuracy can be critical to a patient's long - term prognosis, the study is a step toward automating part of biopsy analysis and improving the efficiency of the process, the researchers say.

«This study looks at trends over time, comparing appropriate patients who all would have been candidates for the SLN biopsy to see how the new procedure was implemented in African Americans and Caucasians.»

These include operations frequently used in patients with chronic liver disease and liver cancer, such as: liver biopsy, percutaneous biliary drainage, portal vein embolization, and portal vein angioplasty,» points out SHIN Kwangsoo, the first author of this study.

While the study did not support earlier findings that sitagliptin was an effective treatment for NAFLD, Loomba said it provided new evidence that clinical trials with patients at higher risk of diabetes do not necessarily need a liver biopsy to be efficiently screened for potential therapeutic agents.

Over the full study period, 62 % of black patients and 74 % of white patients underwent sentinel lymph node biopsy (P <.001).

Two new studies have found that some HER2 - positive and triple - negative breast cancer patients can avoid sentinel lymph node biopsy after neoadjuvant systemic therapy.

A study found that black women were less likely to undergo sentinel lymph node biopsy; photo: biopsy performed on a white patient

The reason why scientists are having difficulty in studying how and why SCLC chemoresistance takes place is that most patients don't have biopsies or surgery when cancer reoccurs.

The benefits of using olfactory receptor neuron samples to study psychiatric disorders and patient responsiveness include their similarity to brain neurons, the relatively easy biopsy procedure, and the potential for scientists to sample and compare cells from the same patients throughout several different stages of disease.

No other patients with BRCA mutations were treated with PARPi and had appropriate biopsies or cfDNA samples available for inclusion in this study.

WASHINGTON (June 30, 2017)-- Based on a new molecular study of tissues biopsied from various parts of the upper digestive tract, researchers at Georgetown Lombardi Comprehensive Cancer Center have identified significant, if subtle, differences in gene mutations and other factors that could help in developing more tailored treatment options for cancer patients.

To further examine systemic antitumor responses, a CALM study extension [21] evaluated sequential tumor biopsies of both injected and noninjected lesions in a cohort of 13 patients.

In the first of the two new studies, Lobo and his team showed that they could obtain lung spheroid cells from human lung disease patients with a relatively non-invasive procedure called a transbronchial biopsy.

In this study, the gluten - intolerant subjects consisted of 78 pediatric patients who had symptoms of celiac disease but normal celiac antibodies (anti-TTG, also called TTG IgA) and normal small bowel biopsies.

This was a retrospective study in which almost 30,000 Swedish patients with biopsy - confirmed celiac disease were compared with controls (people without celiac).

A study published in the December 2010 Journal of Proteome Research finds that «potential» celiac patients with positive blood tests but negative biopsies actually have the same distinctive metabolic fingerprint as diagnosed celiacs.

The study used magnetic resonance metabolic profiling to analyze biochemical markers in the urine and blood of 141 patients: 61 with diagnosed celiac disease, 29 with positive blood tests but negative biopsies, and 51 healthy controls.

Another study looked at patients with celiac disease symptoms whose intestinal biopsies revealed only minor abnormalities, such as Marsh I or II lesions.

Glucosamine Sulfate (GS) Comments Four controlled studies (19, 20, 21, 22) using 750 — 1500 (3 used the 1500) mg / d oral glucosamine sulfate in patients with osteoarthritic knees, showed significant pain reduction, less analgesic use, improved joint function and, in one study improved histology on biopsy.

In one study based on the ultrasound and FNA biopsy researches of Thyroid Multidisciplinary Clinic from the University of Wisconsin came to the conclusion that many of their patients that came for the investigation of their thyroid health issues already had Hashimoto's with or even without their thyroid antibodies elevated and TSH in the normal reference range.

One study conducted in Mexico City's General Hospital found much greater numbers of these mites in biopsies of the skin in patients with rosacea than in people without rosacea.

STUDY THREE — Next we have this study in which scientists performed a skin biopsy on 94 patients: 49 with rosacea, and 45 control subjSTUDY THREE — Next we have this study in which scientists performed a skin biopsy on 94 patients: 49 with rosacea, and 45 control subjstudy in which scientists performed a skin biopsy on 94 patients: 49 with rosacea, and 45 control subjects.

The biology of laryngeal diseases is difficult to study from human patients because access to the organ is difficult, and biopsy is inherently detrimental.

The patients were seen every three months during the nearly four - year study, and liver biopsies were taken at 18 months and 3.5 years to determine the progression of liver disease.