(He's demonstrated this difference by
studying patients with severed spinal cords: Even when these women had no sensation in their clitoris, they could still experience pleasure — and orgasm — through vaginal stimulation.)
What is clear for now, though, is that
studying patients with Sally's deficits can give us valuable insight into how the brain constructs reality.
We would like to consider doing it on a larger scale, maybe having several universities
studying patients with different diagnostic categories to see how a controlled psychotherapy trial produces physical brain changes as a result of treatment.
«While neuroimaging studies can tell us a great deal about the brain's response to complex events, it's only by
studying patients with brain injury that we can see if a brain region is actually needed to perform a given task,» said Dr Clark.
Juno is developing its immunotherapy product candidate, JCAR017, which is in a Phase I trial,
studying patients with B - cell Non-Hodgkin Lymphoma [NHL].
«While
we studied patients with allergic asthma, this research opens the door for the development of new treatments not only for this population, but for those diagnosed with severe asthma as well.»
In
studies patients with diabetes and high blood pressure were given 4 grams of L - carnitine per day in an preliminary study.
Not exact matches
«From 2012 to 2015, the absolute number of
patients treated
with nitroprusside decreased by 53 %, and the number treated
with isoproterenol decreased by 35 %,» wrote the
study authors.
While the new mid-stage
study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest
patients and those
with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.
A two - month 2010
study of nearly 300 cancer
patients at the Mayo Clinic found that those given 1,000 or 2,000 milligrams of ginseng each day reported feeling more energized compared
with those who took a placebo.
We have now completed several health
studies in partnership
with the Geisinger Health System, which provides primary care to over 450,000
patients in Pennsylvania, including many residing in fracking areas.
Finally, in our
study of symptoms, we found
patients with higher unconventional natural gas development activity had higher odds of nasal and sinus, migraine headache and fatigue symptoms compared to those
with lower activity.
A series of preliminary Mayo Clinic
studies conducted in 2010 showed promise for the potential use of a chemical component of green tea (epigallocatechin gallate) in reducing the number of cancer cells in
patients with chronic lymphocytic leukemia.
In the asthma
study, we found increased odds among asthma
patients of asthma hospitalizations, emergency department visits and a medication used for mild asthma attacks
with higher unconventional natural gas development activity, compared to those
with lower activity.
After
studying numerous
patients with circadian rhythms out of sync, he hypothesized that their adrenal glands were overworked and producing lower levels of the hormones needed to cope
with stress.
Patient experiences in the TV drama Grey's Anatomy are, unsurprisingly, portrayed inaccurately when compared
with real - life trauma cases, according to a new
study.
Patients with chronic conditions are 20 percent more likely to be readmitted to the hospital if they also have dementia, according to medical journal
studies.
British - based GlaxoSmithKline, for example, conducts more than 100
studies a year in Canada,
with the participation of some 10,500
patients in more than 1,000 medical centres.
For example, a small
study of 38
patients with Alzheimer's from 2016 looked at the effects of Victoza.
BIIB098: MRI and relapse results from the phase 3 EVOLVE - MS - 1
study in
patients with relapsing and remitting multiple sclerosis were presented at the 70th annual meeting of the American Academy of Neurology (AAN).
In a
study cited in Shawn Achor's book The Happiness Advantage, three groups of
patients treated their depression
with medication, exercise, or a combination of the two.
ALKS 3831: Enrollment completed for ENLIGHTEN - 2, a six - month weight
study compared to olanzapine in
patients with stable schizophrenia.
After that, Watson will take assist by providing both physician and
patient with a report that includes the most relevant drug trial and academic
studies for their specific conditions.
A recent
study tested 79
patients, outfitting one - third of them
with a VR headset depicting a coastal scene, one - third
with a VR cityscape and the remaining third
with no VR at all.
The
study offers more validation for the use of remote
patient monitoring (RPM) wearables and devices to provide clinicians
with fuller, more accurate
patient data.
Other
studies, meanwhile, are examining tryp's potential efficacy as an antifungal agent; and as a prognostic indicator in
patients with brain cancer (as seen by increased uptake of the amino acid on a PET scan).
A sleep
study conducted by Dr. Marcel Hungs on
patients with chronic back pain using Celliant found the median time
patients spent awake after falling asleep was reduced by 18.3 minutes.
An early, outsourced clinical research
study with real
patients was encouraging, but there are many potential pitfalls yet to come, said University of North Carolina diabetes researcher Dr. John Buse, who was briefed by Google on the lens last week.
It may have to do
with Addyi's high pricing (on par
with Viagra at $ 26 per pill without an assistance program), its daily intake requirement (unlike Viagra, it adds up to $ 780 per month), its potentially deleterious side effects (low blood pressure and fainting), its restrictions on alcohol consumption (abstinence vs. large quantities not recommended for Viagra
patients), a 10 % efficacy rate (whereas Viagra works 50 % of the time compared to a placebo, according to a recent
study), and its subtle neurotransmitter - targeting mechanism (contrast that to the obvious hydraulics of Viagra).
«More than twice the number of
patients [were] still living at the end of the
study after receiving IMAB362 plus chemotherapy compared to chemotherapy alone,» according to Ganymed CEO Özlem Türeci,
with patients showing the highest level of that protein biomarker responding best to the treatment.
Fernando Pagan, a GUMC associate professor of neurology who directs the Movement Disorders Program at MedStar Georgetown University Hospital, said that to his knowledge, the
study «represents the first time a therapy appears to reverse — to a greater or lesser degree depending on stage of disease — cognitive and motor decline in
patients with these neurodegenerative disorders.»
The technology has proved to be quite effective in
studies — Embrace's algorithm detected 100 % of the seizures in a multi-site clinical
study of 135
patients diagnosed
with epilepsy.
REDUCE - IT is the first multinational cardiovascular outcomes
study evaluating the effect of prescription pure EPA therapy, or any triglyceride - lowering therapy, as an add - on to statins in
patients with high cardiovascular risk who, despite stable statin therapy, have elevated triglyceride levels (150 - 499 mg / dL).
A large portion of the male and female
patients enrolled in this outcomes
study are anticipated to also be diagnosed
with type 2 diabetes.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations
with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror
patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured
patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and
patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical
studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination
with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed
with the U.S. Securities and Exchange Commission (the SEC).
Dr. Saxon, who spoke
with me after her SWSW panel Biometrics and Identity: Beyond Wearable, said that her institution soon will launch a ResearchKit app for an existing
study that tracks
patients after atrial fibrillation repair surgery.
The company's leading program, a differentiated PPAR gamma agonist (MIN - 102) that has multiple CNS indications, has successfully completed a phase 1 clinical trial and is ready to move into a phase 2/3
study with adult AMN
patients.
April 16 Merck & Co's immunotherapy Keytruda plus chemotherapy significantly improved overall survival versus chemotherapy alone in newly - diagnosed
patients with advanced non-small cell lung cancer in a highly - anticipated
study that appears to cement the company's lead in the most lucrative oncology market.
While Tecentriq's results in Imvigor211 were consistent
with its previous
study, Roche said,
patients getting chemotherapy in the latest trial survived longer than anticipated.
JCAR015 is a CD19 - directed chimeric antigen receptor technology (CAR - T) product candidate that has been under
study in ROCKET in adult
patients with relapsed or refractory B - cell acute lymphoblastic leukemia.
Presentations will highlight the short and long - term effects of Ingrezza on tardive dyskinesia symptoms by body region, long term safety and efficacy data from the KINECT 4 phase 3 open label
study and also from RE-KINECT (real - world screening
study of
patients with possible TD).
The biotech specialist said that its updated phase 2 data in a
study of its poziotinib candidate treatment for non-small cell lung cancer resulted in a preliminary confirmed objective response rate and potential progression - free survival benefit in
patients with the EGFR Exon 20 Mutant form of the disease.
The
study evaluated 344
patients and was randomized,
with 321 receiving a
study intervention; 163, angiotensin II; and 158, a placebo.
Patisiran was being evaluated in a late - stage
study against a placebo for the treatment of
patients with hereditary ATTR (hATTR) amyloidosis
with polyneuropathy.
During a
study that led to Dupixent's approval, injections every other week, combined
with topical steroid creams helped 69 % of
patients achieve 75 % clear skin, after 16 weeks of treatment.
If one has never journeyed into the deep — prayed (which includes Scripture / theological
study, faith sharing, adoration, spiritual formation / retreats, pilgramages, Mass, reconciliation, fasting, listening for God's voice, and more) on an ongoing fashion or done God's will (been obedient,
patient, humble, unconditionally sacrificing, unselfish) to the extent that they understand what it means to be Catholic and God being your number one priority — that His Ways and those of His Church are not the ways of the world (trade vices for virtues) and that we are being called into communion
with Him via love for Him and one another in our faith community and broader community — then it is no wonder some are lost or disillusioned.
A
study of cardiopulmonary resuscitation (CPR) at a well - respected Boston hospital revealed that physicians rarely discussed CPR
with their
patients, despite the fact that one - third of
patients who die in the hospital first undergo CPR.
A
study of the
patients visited regularly by the students (compared
with a matched control group of other
patients) showed that the program had made a significant difference in the general improvement and discharge rate of those visited.
About 1971, however, there was a major turn in my pilgrimage as I gradually became painfully aware of the so - called outcome
studies reporting the dubious effectiveness of average psychotherapy, whose cure rates barely match spontaneous remission, coupled
with the frightening spectre of client deterioration (i.e.,
patients finding their condition worsening under the care of professional psychotherapists).
The
study echoed this point as some GPs reported feeling frustrated by having little to offer
patients with complex problems driven by social and emotional difficulties anything other than pills.