«There is so much we can learn by
studying simple organisms.»
In addition, we will
study another simple organism — the fruit fly — to elucidate how the entire brain coordinates behavior in the face of an ever - changing environment.
Not exact matches
The complexity of mammals led Kandel to try to find a
simpler organism to use in his
studies.
Scientists knew that fruit flies, cockroaches, and other
simple organisms have sensory processors that resemble a cortex, but these were «always interpreted as a striking example of convergent evolution of unrelated structures,» says molecular biologist Raju Tomer, who led the
study at the European Molecular Biology Laboratory in Germany.
But while this
study has proved that the technique works in a
simple organism, it could also be applied to other bacterial species, yeast or even human cells to find useful information about how genes are controlled and how they can be manipulated.
«This
study is a beautiful example of how relatively
simple bioinspired robots can address [questions] that are difficult or impossible to test in living
organisms,» says Brandon Jackson, an evolutionary biologist at the University of Montana, Missoula.
It also offers an opportunity to
study learning types in other very
simple organisms, such as viruses or bacteria.
Rao's team next tested how these variant forms of NHE9 would affect a relatively
simple organism often used in genetic
studies: yeast.
Many researchers assumed the
organism was too
simple to serve as a good model when
studying the complexities of neurodegenerative diseases.
The
study provides new insights in how eukaryotic
organisms gradually evolved from
simpler microbial ancestors.
As one of the three initial cores established when the Buck Institute was founded, the Genomics Core has played a vital role in helping shape investigations in the basic molecular biology of aging, from assisting in the investigation of how specific drugs can extend lifespan in
simple model
organisms such as the nematode C. elegans, to facilitating
studies in various animal models of age - related disease.
Technologies to visualize neurons in live subjects — as well as process such gargantuan volumes of data — do not yet exist, so only post-mortem
studies in
simpler organisms are even presently imaginable.
His
studies focus on the fundamental mechanisms of aging in
simple organisms and mice and on how they can be translated to humans.