Sentences with phrase «studying these phases more»

Not exact matches

A 2016 study by health and environmental organizations found phasing out coal by 2030 would prevent more than a thousand premature deaths and some 870 hospital visits in Canada, while saving nearly $ 5 billion in costs to society, including healthcare expenses and lost productivity.

However, development costs will likely rise, however, as the «DepoVax pipeline expands into other medical markets beyond oncology and infectious disease» and «existing programs advance into more substantive Phase 2 studies, perhaps as early as FY H2 / 18.»

But a recent study found that elevated concentration of capsaicin, the actual compound which makes hot peppers hot, caused much more prostate cancer cells to freeze in a non-proliferative phase.

Studies have also shown that worn babies are happier and spend more time in the quiet alert phase.

In this study, the 95th percentile rate of active phase dilation was substantially slower than the standard rate derived from Friedman's work, varying from 0.5 cm / h to 0.7 cm / h for nulliparous women and from 0.5 cm / h to 1.3 cm / h for multiparous women (the ranges reflect that at more advanced dilation, labor proceeded more quickly)(Table 2).

A study of more than 500 women found that extending the minimum period of oxytocin augmentation for active phase arrest from 2 hours to at least 4 hours allowed the majority of women who had not progressed at the 2 - hour mark to give birth vaginally without adversely affecting neonatal outcome (22).

A study by two bipartisan groups estimated that the country's poorest families would lose more than $ 2,500 in average annual health care benefits once the legislation was fully phased in, illustrating the political challenge the GOP bill poses.

During the meeting, Borough President Katz also noted the one year anniversary of the Jamaica NOW Action Plan's April 15, 2015 launch and outlined major milestones of the Jamaica NOW Action Plan in the past year, including the activation of the Bronx - Flushing - Jamaica Q44 Select Bus Service that serves 44,000 New Yorkers daily; the newly - restored paths at Rufus King Park that are part of the first phase of the Park's major capital improvements; redesigned storefronts of local businesses along Sutphin Boulevard (with more on the way); a $ 138,000 «Building Community Capacity» grant toward the formation of the Jamaica Arts Alliance; the release of an RFP to activate the 168th Street Garage into a new, mixed - use development, with the City to announce the winning bid shortly; the launch of the «Jamaica Avenue Streetscape Improvements» study to determine the cost and scope of additional seating, increased plantings and improved pedestrian circulation in the area; and free public Wi - Fi on track by July in the Downtown Jamaica Corridor, the first area in Queens to host LinkNYC.

However, during the non-blinded phase of the study, muscle - related symptoms were 41 % more common among people taking statins compared to those who weren't (1.26 % vs 1.00 % per year respectively).

This work is still in early phases; more study is needed.

The novel substance BIIB074 which was tested in this phase II study inhibits the sodium channel 1.7 state - dependent, meaning: The more active this sodium channel gets, the stronger it is blocked by BIIB074.

«The results of the phase III clinical trial show that a target fusion biopsy detects more clinically significant prostate cancer,» said Art Rastinehad, DO, principal investigator of the study and director of interventonal urologic oncology at North Shore - LIJ's Arthur Smith Institute for Urology, in New Hyde Park, NY.

But a later study reported that body temperature can be off by as much as 5 hours from circadian phase, so Wright and Czeisler tracked levels of the nighttime hormone melatonin, thought to be a more precise measure.

In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.

The meta - analysis examined 394 non-cancer, phase I studies comprising 11,028 healthy, compensated, voluntary participants (4,620 unique individuals, some of whom participated in more than one study) conducted between September 2004 and March 2011 at Pfizer Inc.'s three worldwide dedicated phase I testing sites in Belgium, Singapore and the United States.

A randomized phase III trial finding that a new monoclonal antibody, elotuzumab, added to standard therapy, extended the duration of remission for patients with relapsed multiple myeloma by about five months Findings from two phase III studies showing that children with Wilms tumor who have a specific chromosomal abnormality do better with a more intensive, augmented chemotherapy regimen

Despite the fact that more than 100,000 healthy people annually participate in non-oncology phase I studies worldwide, there is little systematic research quantifying their risks.

«Studying the formation and evolution of jets in metals and, more generally, how materials at extreme conditions respond using X-ray phase contrast imaging is relevant to such things as meteorite impacts, the performance of explosives and detonators, understanding crack nucleation and propagation in materials, and the development of new materials with tailored properties whose applications include automotive and airplane components, lighter and more impact - resistant armor, and debris shields in space, to name a few.»

Since CGP3466B has already been tested in phase II clinical trials to (unsuccessfully) treat Parkinson's disease and ALS, it is known to be safe for humans, but the researchers caution that many more years of studies are needed to definitively show whether it is effective for preventing cocaine damage, first in mice, then in humans.

A new phase 3 study in some of the most difficult - to - treat patients, women with endocrine - resistant disease, showed that the newly approved drug, palbociclib, more than doubled the time to cancer recurrence for women with hormone - receptor (HR +) positive metastatic breast cancer.

Women in the early phases of menopause are more likely to have trouble sleeping during certain points in the menstrual cycle, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

«We found that perimenopausal women experience more sleep disturbances prior to menstruation during the luteal phase than they did during the phase after menstruation,» said one of the study's authors, Fiona C. Baker, PhD, of the Center for Health Sciences at SRI International in Menlo Park, CA, and the University of the Witwatersrand in Johannesburg, South Africa.

With approximately two - thirds of responders to AF - 219 treatment showing more than a 50 % reduction in cough frequency, we plan to advance the development of AF - 219 by initiating a Phase 2b study in patients with chronic cough early next year and to initiate other studies in preparation for registration studies.»

But new studies show that, if anything, the measures haven't been strict enough: A more rigorous culling policy in the first phase of the epidemic could have saved millions of animals, the researchers say.

BAT is still in the research phase and requires more studies with a larger, more varied population, but another approach — allergen - component testing — has already been approved by the U.S. Food and Drug Administration for peanut allergies.

Previous studies have suggested that Arctic sea - ice loss causes the NAO to spend longer in its «negative phase» - generating more easterly winds that bring colder air from Scandinavia and Siberia to the UK.

Just 1 week after news broke about a clinical research tragedy in France, more details have emerged about what happened at the private research company in Rennes where the phase I study took place.

Knight says some of the strongest evidence for a bacterial role in circadian - linked diseases lies in the final phase of the study, when the research team analyzed fecal samples from two people on a normal schedule and two more who had recently flown from the United States to Israel.

A larger ongoing phase 3 study (SONAR; ClinicalTrials.gov identifier NCT01858532) will shed more light on the kidney and cardiovascular protective effects of atrasentan.

Wong was not involved in the study, but he is part of a team of researchers currently testing the device in a phase III clinical trial, which includes more than 200 glioblastoma patients in the United States and Europe.

In this Phase 2a study, significantly more guselkumab - treated patients achieved ACR 20/50/70 responses and Psoriasis Area Severity Index (PASI) 75/90/100 responses at week 24.

Blueprint will see where it stands after adding more patients with different cancer types to the Phase 1 study and focusing more on how long their responses last, rather than just whether they respond at all.

For example, while still in its scientific checkout phase, scientists using ALMA have found evidence for Earth - mass planets around nearby stars; as it nears its full complement of 66 antennas, ALMA will deduce the presence of many more exoplanets and study the chemical composition of the planetary nurseries.

And a study by Rahmstorf (2003) also concludes that the LIA may be the most recent cold phase of the D - O cycle, and his research suggests that the 1,470 - year periodicity is so regular that it's more likely due to an orbital cycle than a solar cycle.

The new phase three study of the cervical cancer vaccine is needed for the FDA to consider approving it for more widespread use, said Ghamande, a principal investigator on the trial.

More than half of patients (58 %) in both study phases had grade 3 or worse treatment - related adverse events.

Enterome's EB8018, a First - in - class Drug Candidate Targeting Crohn's Disease, Successfully Completes Phase I Study in Healthy Volunteers — Enterome — Cision (same as above link, more detail)

The scientific goal of the Developmental Cancer Therapeutics Program is to discover and characterize unique agents and pathways that will impact the development of more effective cancer therapies and to translate these discoveries into clinical applications by using proof - of - principle, early phase clinical and correlative science studies.

But all of these studies, including more than 25 phase II and III clinical trials, have failed to offer significant benefit to patients.

His most important contributions include theory of high harmonic generation by low frequency laser fields and atto - second physics, quantum optics of dielectric media, studies of Bose - Einstein condensates and their excitations (solitons, phase fluctuations), theory of entanglement, and more recently studies of strongly correlated many body atomic and quantum optical systems.

A phase III study of TTFields following Stereotactic Radiosurgery for 1 - 10 Brain Metastases from Non-Small-Cell Lung Cancer more...

He is a co-investigator in a number of clinical trials at the Huntsman Cancer Institute and is working to bring more studies of all phases to benefit his patients to the Huntsman Cancer Institute.

And studies report that we tend to eat more calories (anywhere from 90 to 500 more per day) during this phase.

According to the studies researching the effects of HIIT, it was concluded that HIIT practitioners even in their post-recovery phase were producing 450 percent more HGH, enabling them optimal muscle building and fat loss results.

In summary, this study found that a combination program consisting of heavy weights / low reps and light weight / high reps was more effective for improving both strength and endurance than a traditional periodized training program consisting of a single rep range during each training phase.

After eight weeks, 34 of the people who practiced the relaxation response — a little more than half — had achieved a systolic blood pressure reduction of more than 5 mm Hg, and were therefore eligible for the next phase of the study, in which they could reduce levels of blood pressure medication they were taking.

Using the Center for Epidemiological Studies of Depression scale, the researchers found that the probability of a high depression score (more than 16) was 4-fold greater during the menopausal transition than during the premenopausal phase.

* Duration of a few weeks * An average dose more equivocal to a «loading» phase than a «maintenance phase» * A larger dose for potential responders who lack natural, dietary creatine * A smaller dose for potential non-responders with a significant amount of existing dietary creatine intake * A training protocol that emphasizes all phases of muscular energetics to take advantage of the ATP - CP, glycolytic, and oxidative effects of creatine supplementation (HIIT is ideal for cardiovascular exercise when supplementing creatine, due to the repeated bouts of high intensity work) * A training protocol that incorporates negatives in order to stimulate satellite cell fusion, as per Dr. Hatfield's theory of holistic training * A training protocol that emphasizes repeated bouts of work per the results of creatine studies * A nutrition protocol tailored to reduce post-workout cortisol levels, which would involve a post-workout shake and possible glutamine supplementation * A nutrition protocol that takes advantage of carb - load (super compensation) near the end of the cycle

However, as a whole HMB appears to be effective in a majority of studies with longer - duration, more intense, periodized training protocols and may be beneficial to bodybuilders, particularly during planned over-reaching phases of training [164].

Adhering to these traditional concepts the US Department of Agriculture has concluded that diets, which reduce calories, will result in effective weight loss independent of the macronutrient composition, which is considered less important, even irrelevant.14 In contrast with these views, the majority of ad - libitum studies demonstrate that subjects who follow a low - carbohydrate diet lose more weight during the first 3 — 6 months compared with those who follow balanced diets.15, 16, 17 One hypothesis is that the use of energy from proteins in VLCKD is an «expensive» process for the body and so can lead to a «waste of calories», and therefore increased weight loss compared with other «less - expensive» diets.13, 18, 19 The average human body requires 60 — 65 g of glucose per day, and during the first phase of a diet very low in carbohydrates this is partially (16 %) obtained from glycerol, with the major part derived via gluconeogenesis from proteins of either dietary or tissue origin.12 The energy cost of gluconeogenesis has been confirmed in several studies7 and it has been calculated at ∼ 400 — 600 Kcal / day (due to both endogenous and food source proteins.18 Despite this, there is no direct experimental evidence to support this intriguing hypothesis; on the contrary, a recent study reported that there were no changes in resting energy expenditure after a VLCKD.20 A simpler, perhaps more likely, explanation for improved weight loss is a possible appetite - suppressant action of ketosis.