Sentences with phrase «subcellular compartmentalization»
Therefore, subcellular compartmentalization of Ras - GEF and Ras upon TCR stimulation is now widely accepted to be the branch point of positive and negative selection (11).
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Our technological expertise ranges from the most fundamental approaches to study membrane transport in lymphocytes and dendritic cells (subcellular compartmentalization, intravital microscopy, phagosomal functions), the systematic analysis of gene expression and it regulation (RNAseq, Chip Seq, proteomics) and physiological and pathological immune responses (mouse models for cancer immunity, immunomodulation / vaccination, human clinical studies in cancer).