Sentences with phrase «subcutaneous depots»

Animals were weighed and adipose tissues (epididymal or parametrial, perirenal, mesenteric, and inguinal subcutaneous depots), liver, and extensor digitalis longus muscle were removed.

The scatterplot data suggest that macrophage accumulation in the subcutaneous depot may plateau at high degrees of adiposity, or that abnormalities associated with leptin deficiency may cause decreased macrophage accumulation specifically in the subcutaneous depot (Figure 3d).

Although the slopes corresponding to adipocyte cross-sectional area for the subcutaneous depot were smaller than (and fell outside the 95 % confidence intervals of) the slopes for the mesenteric and perigonadal depots, this difference was entirely attributable to the fact that the data from three B6.V Lepob / ob mice fell below the line relating adipocyte area to macrophage content in the other animals (Table 1).

Part of this is a pathological redistribution of adipose from the subcutaneous to the visceral depot, but it now emerges that the subcutaneous depot becomes qualitative as well as quantitatively abnormal in the degenerative aging process also suffers genuine age - related lipoatrophy and lipodystrophy — and that p16Ink4a - driven cellular senescence is at the heart of it.

Not exact matches

Subcutaneous brown fat depots can also be found in the vicinity of neck muscles, the clavicles, and abdominal wall.

Or they may be able to insert subcutaneous fat — which, in addition to serving as an energy bucket, «may be making some beneficial substance» — into depots of visceral fat.

In mice, both body mass and adipocyte size were strong predictors of the percentage of F4 / 80 + macrophages in the perigonadal, perirenal, mesenteric, and subcutaneous adipose tissue depots.

We calculated the average adipocyte cross-sectional area and the percentage of F4 / 80 - expressing cells in the perigonadal, perirenal, mesenteric, and subcutaneous inguinal adipose tissue depots from Ay / + female, Lepob / ob female, lean male, and diet - induced obese (DIO) male mice.

Adipose tissue distribution between visceral and subcutaneous fat depots was unaltered, with no change in adipocyte cell size.

If you had a poor diet and neglected physical activity, chances are that your body will start storing fat into other depots, like the deep subcutaneous layer.

One theory proposes that once the storage capacity of subcutaneous adipose tissue (SAT) depots is exceeded under conditions of energy excess, either as a result of impaired expandability and / or excessive hypertrophic growth, fat deposition within visceral depots and non-adipose tissues including the liver, skeletal muscle and pancreas can ensue.93 This can subsequently lead to the development of systemic IR and a series of associated cardiometabolic disorders including dyslipidaemia, dysglycaemia, hyperinsulinaemia and hypertension.3 Expression of pro-inflammatory mediators including interleukins 1 (IL - 1), 6 (IL - 6), tumour necrosis factor alpha (TNF - α) and resistin, are also increased which can further potentiate IR and promote atherosclerosis.