Sentences with phrase «subgroup of patients with»

Prevalence, assessment and diagnosis: NMDA receptor antibodies are found in a small subgroup of patients with first - episode psychosis, but their clinical relevance is unknown

NMDA receptor antibodies are found in a small subgroup of patients with first - episode psychosis, but their clinical relevance is unknown

Importantly, they also noted that there weren't even benefits to raising cortisol in the subgroup of patients with the lowest cortisol levels.

The investigators also looked at a subgroup of patients with familial hypercholesterolemia, a genetic disorder that causes extremely high cholesterol that increases the risk of early heart disease.

This could help identify a subgroup of patients with similar cell features and match them to the appropriate therapy, Finkbeiner suggests.

This could help identify a subgroup of patients with similar cell features and match them to the appropriate therapy.

A subgroup of patients with NAFLD progresses to the inflammatory subtype of the disease called non-alcoholic steatohepatitis (NASH).

To date, the only known disease related to gadolinium injections is nephrogenic systemic fibrosis, a condition only occurring in a tiny subgroup of patients with renal failure.

In addition, the subgroup of patients with unmethylated MGMT promoter and HLA - A2 appear to particularly benefit,» said Patrick Y. Wen, MD, director of the Center for Neuro - Oncology at Dana - Farber Cancer Institute and professor of Neurology, Harvard Medical School, who will present the data at the conference.

We can not make robust conclusions because the subgroup of patients with negative EGFR was very small, but the hypothesis generated here is that those tumours do not respond well to necitumumab.»

The current study analysed outcomes in the subgroup of patients with EGFR expressing tumours compared to those with no EGFRs.

Many international care guidelines call for further research addressing the different subgroups of patients with lower back pain.

Now researchers at SciLifeLab, together with international colleagues, have discovered a new correlation between specific molecular features of the disease and subgroups of patients with different prognosis.

Not exact matches

As treatments for HCV have evolved, genotype 3 patients have become the most difficult subgroup of patients to cure.1 Although there have been recent advances in direct - acting antiviral therapies for HCV genotype 1, genotype 3 remains a challenge and is a highly prevalent strain of the infection globally, with a particularly high concentration of cases in Asia.1

This imaging approach could also, in the future, help better define which patients with autoimmunity will likely progress to diabetes and classify subgroups of patients who might benefit from different therapeutic strategies.

Efforts to better understand patients with these symptoms have largely failed, says Aucott, because patients grouped under the umbrella term «chronic Lyme disease» could belong to one of various subgroups.

Clinical features of major depressive disorder (MDD) may help identify specific subgroups of depressed patients based on associations with genetic risk for major psychiatric disorders, reports a study in Biological Psychiatry.

In terms of cognitive disability, the researchers found that in the subgroup of MS patients who underwent neuropsychological testing, those with more cerebral microbleeds had higher disability on verbal and other cognitive function tests.

Commenting on the findings, Prof Robert Pirker, programme director for lung cancer at the Vienna General Hospital in Vienna, Austria, not involved in the study, said: «This subgroup analysis shows that the effect of necitumumab was slightly greater in patients with EGFR expressing tumours than it was in the entire SQUIRE population.

The authors conclude that FL118 - based therapy may be beneficial for a subgroup of cancer patients with tumors such as chronic lymphocytic leukemia and melanomas, in which MdmX overexpression confers treatment resistance.

Our tentative, though testable, findings may provide a direction for the development of personalized treatments for a patient subgroup whose illness is associated with a dysregulation of brain glutamate function.»

The map works by dividing asthma into different subgroups in order to allow personalised treatment more targeted to the type of asthma patients live with.

«These molecules» existence can also be used to classify cancer patients into subgroups of individuals with different survival outcomes,» adds Jones.

«This paper is an important addition to the view that inflammation is a feature of the neurobiology of a subgroup of depressed patients, in this case the group with suicidal ideation,» said Dr. John Krystal, Editor of Biological Psychiatry.

«Detection of ctDNA allows identification of a subgroup of patients at high risk of early relapse and inferior survival, allowing stratification of patients to adjuvant regimens associated with higher toxicity but greater potential for efficacy.»

Subgroup analyses showed benefit with the combination in all groups, with the exception of those with brain metastases at baseline, though this included a total of only 12 patients.

Intensive blood pressure (BP) control reduced the risk of cardiovascular (CV) events by 21 % compared with standard BP control in a subgroup of patients from the ACCORD - BP trial who had type 2...

Through these studies, she has redefined the molecular map of breast cancer, resulting in the discovery of novel patient subgroups with distinct clinical outcomes.

We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.

There were also no clear differences in the association between statin use and outcomes in analyses stratified by age older or younger than 55, 60, 65, or 70 years, with very similar estimates from 7 trials (eTable 6 in the Supplement).14, 19,20,26,29,31,35 None of the trials that enrolled patients older than 75 years18, 20,22,23,27,29 reported results in this subgroup.

It was small, and the findings can't be applied to certain subgroups of patients who were excluded from the study (such as those with severe depression who may be suicidal), to primary care settings, to forms of dementia other than Alzheimer's, or to other types of antidepressants.

The combination therapy of GH and IGF - I might be beneficial in growth retardation, in certain specific subgroups of critically ill or catabolic patients and in the treatment of GH - deficient subjects with the metabolic syndrome and / or manifest diabetes.

Lin, Y. S., Lin, L. C., and Lin, S. W. Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow - up of a double - blind randomized study with subgroup analysis.

Levels of fatigue and physical functioning among patients with CFS were unrelated to the four subgroups in this study.