A
"subpopulation" refers to a smaller group within a larger population that has distinctive characteristics or differences compared to the rest of the population.
Full definition
As I discussed in my last post, the Gulf of Boothia
subpopulation in the central Canadian Arctic has the highest density of polar bears anywhere in the world.
Over the recent years, immense progress has been made in defining individual CD4 T cell
subpopulations with distinct functional and developmental properties.
The ability to map «epigenomes» using such a small number of cells will be valuable to cancer research, since the epigenetic landscape is dramatically rearranged in cancer and contributes to phenomena driven by
small subpopulations of cells, such as drug resistance and metastasis.
As cells divide and differentiate, changes in transcriptional profile occur, leading to considerable phenotypical diversities forming
different subpopulation of cells and tissues in living organisms.
Several factors may contribute to differential opportunities to learn mathematics and, ultimately, discrepancies between students» mathematics achievement in the United States and their international counterparts (Mullis, Martin, Foy, & Arora, 2012), as well as between
subpopulations within the United States (National Center for Education Statistics [NCES], 2013).
Monitoring of
subpopulations by trapping confirms a continuing decline, except that abundance remains relatively high on Bruny Island.
Alternatives include collecting valuable data from subsistence harvests, using remote methods to track changes in habitat, and selecting
specific subpopulations as indicators.
Biophysical properties and responses to glutamate receptor agonists of
identified subpopulations of rat geniculate ganglion neurons
«These results provide an unprecedented window into the cellular dynamics of tumor evolution and suggest that interactions
between subpopulations of tumor cell types contribute to metastatic progression from initial tumors,» Stanger said.
To compare the rate of proliferation under the same condition as the parental and hypoxia - exposed adherent cells, we plated the cycling hypoxia - selected
subpopulation as adherent cells (adherent MDA - MB 231 F3 and adherent BCM2 F3) and measured the increase in cell numbers together with the other adherent cell populations.
While CER findings may not be used to determine Medicare coverage, they can be considered by the Centers for Medicare & Medicaid Services after public comment and the consideration of effects
on subpopulations for which the findings may have limited validity.
This is at least suggested by the observation that the
mesenchymal subpopulation in the HMLE model remains viable upon most chemotherapeutic treatment regimens, under conditions that allowed the effective elimination of the epithelial population [7].
Collectively, our results support the idea that a stem -
like subpopulation in the tumor could expand selectively in response to changes in the microenvironment.
Several recent
subpopulation estimates have shown an increase between one estimate and another of greater than 30 % yet deemed not to be statistacally significant due to large margins of error.
This suggests that the size of the
SB subpopulation declined between the late 1990s and 2006, although low precision in the previous estimate of 1,800 precluded a statistical determination.
Herlyn's working hypothesis is that defined
tumor subpopulations are central to dormancy and drug resistance due to their slow turnover and their non-responsiveness to growth signals.
«On short time scales, we can have variable responses to the loss of sea ice
among subpopulations of polar bears,» Laidre said.
These studies will lead to in - depth investigations of tumor heterogeneity and the dynamic regulation of genes that
define subpopulations with specialized biologic functions.
The
other subpopulation preferentially imports lactate, using it as the main energy source by harnessing part of the citric acid cycle.
As expected, this
novel subpopulation showed increasing viability under hypoxia and the ability to proliferate as either an adherent monolayer or substrate - independent tumor spheres.
This is especially problematic when performing
subpopulation studies on mixed samples as it is not informative regarding which cell responds to which drugs or clinical treatments.
In addition to miRNA200c and miR205, the cycling hypoxia - selected
subpopulation showed decreased miR215 expression (Figure 6e).
Hence, BH3 mimetics might represent an attractive approach of eliminating
resistant subpopulations of cancer cells, thereby targeting both tumor cell invasion and cancer relapse.
Based on nearly two decades of research, we believe that
particular subpopulations of neurons have the unique ability to integrate and repair dysregulated neural circuits.
«Because the Hawaiian hoary bat is the only living native land mammal in Hawaii and it's on the U.S. Fish and Wildlife Service's endangered species list, we want to know everything possible about its genetic history, relationships to other bats and if there are
unique subpopulations on different Hawaiian islands,» Russell said.
«We were able to boost fluorescence accumulation in the highly tumorigenic low - fluorescence glioma stem cell
subpopulation using a clinically approved iron chelator,» co-corresponding author Kouichi Tabu says.
Therefore, we hypothesize that hypoxia / reoxygenation cycles may provide the driving force to select for a highly metastatic breast
CSC subpopulation.
HV cells cultured under self - renewing conditions were subjected to flow cytometry to separate Venus positive and
negative subpopulations within the SSEA - 1 positive fraction.
One
subpopulation exhibits the Warburg effect, favoring glycolysis and generating lactate along with those useful intermediates.
Additionally, identifying at -
risk subpopulations within these areas and understanding what drives that risk is crucial.
ESSA legislation puts additional pressure on schools and districts to be accountable for raising graduation rates for students
across subpopulations.
While the parental and hypoxia - exposed adherent cells display similar rates of proliferation, the cycling hypoxia - selected
subpopulations grow slower as adherent cells and even slower as suspension cultures (Figure 4c).
If the current trend of overexploitation continues, it is certain that
several subpopulations of S. leytensis will soon collapse.
As a result, tiger
subpopulations also became significantly more fragmented, greatly increasing their threat of extinction in each individual forest and as a species.?
Heteroresistance is caused by a
minor subpopulation of resistant bacteria which are genetically identical to the rest of the susceptible bacteria.
A T - cell marker panel that can identify subsets of tumor - associated T - cells allows scientists to identify and
target subpopulations of T - cells playing unique roles in the immune response against a tumor.
Phrases with «subpopulation»