Sentences with phrase «subpopulation using»

Importantly, these devices also will open up new approaches to drug development not possible with animal models today, such as personalized medicines and development of therapeutics for specific genetic subpopulations using chips created using cells from particular patients.»

Not exact matches

The paper, to appear Sept. 14 in The Cryosphere, is the first to quantify the sea ice changes in each polar bear subpopulation across the entire Arctic region using metrics that are specifically relevant to polar bear biology.
«Greater effort to track concussions using large - scale epidemiological data are needed to identify high - risk subpopulations and monitor prevention efforts,» the researchers wrote.
Using a technique known as single - cell RNA sequencing, the team explored more than 65,000 individual cells that exist under normal or inflammatory conditions, looking for genes that were more active in one state or subpopulation versus another.
Using data collected from adult females in 11 subpopulations of polar bears across the Arctic, Regehr and Laidre's team calculated the generation length for polar bears — the average age of reproducing adult females — to be 11.5 years.
Alternatives include collecting valuable data from subsistence harvests, using remote methods to track changes in habitat, and selecting specific subpopulations as indicators.
In particular, they focused on subtle genetic variations that can be used to differentiate these corals into subpopulations.
The samples were then analyzed with a technique called polymerase chain reaction (PCR), used to amplify specific nuclear «microsatellites» for statistically measuring gene flow between the different populations and subpopulations located in the western South Atlantic (Breeding Stock A) and the eastern South Atlantic and Indian Ocean populations (Breeding Stocks B and C, and the Arabian Sea humpback whale population, respectively).
The other subpopulation preferentially imports lactate, using it as the main energy source by harnessing part of the citric acid cycle.
Using an in vitro proxy assay, i.e. the ability of single cells to generate multicellular spheres in suspension (mammosphere assay), it was determined that the mesenchymal subpopulation of HMLE cells is enriched for mammosphere - forming cells.
Using a qRT - PCR - based method, we found dramatic decreases of epithelial miRNAs (miR200c and miR205) in the F3 subpopulations compared with the parental breast cancer cell lines (Figure 6e).
The Student t test was used to calculate the significance of increased CD44 + / CD24 - / ESA + and E-cad - / CD44 + / CD24 - populations in the cycling hypoxia - selected subpopulations.
Colony formation assays were used to assess the ability of this subpopulation to self - renew.
Both 3DISCO and CLARITY have relied on the use of transgenic mice in which a subpopulation of neurons are brightly labeled with GFP (e.g. Thy1 - YFP - H mice).
Using single - cell transcriptomics, we identified a distinct subpopulation of old HSCs carrying a p53 signature indicative of stem cell decline alongside pro-proliferative JAK / STAT signaling.
Here we use long - read sequencing to generate end - to - end genome assemblies for 12 strains representing major subpopulations of the partially domesticated yeast Saccharomyces cerevisiae and its wild relative Saccharomyces paradoxus.
If subpopulation, lets say, adapted to low CHO, then more CHO might lead to bunch of more or less stealth problems, from indigestion over hyperinsulinemia to microbiota rebalancing (which, now we know, release some neurotransmitters on its own and thus influence not only physical health but behavior apart from their ability to use or create nutrients we need).
Now the analysis in this study was kind of fancy and interesting but for our purposes the important data was analyzed using the entire sample and then in a subpopulation of those that adhered all the way through the study.
Instead, for this «at risk» subpopulation, familiarity with the internet, actively looking for a partner, and knowing someone who has used internet dating are strong proximate determinants of internet dating.
Similarity by racial makeup calculates the five cities with the lowest total differences in Hispanic, Black, White, and Asian subpopulation percentages using a euclidean distance calculation, or the difference between two points using a straight line.
Using new strategies and tools, TEA staff streamlined efforts, made sure adequate resources for data analysis were in place, examined gaps and subpopulations and ensured data were reported to stakeholders using innovative visualization techniUsing new strategies and tools, TEA staff streamlined efforts, made sure adequate resources for data analysis were in place, examined gaps and subpopulations and ensured data were reported to stakeholders using innovative visualization techniusing innovative visualization techniques.
These student - centered uses had a stronger showing in the data disaggregated by subpopulation.
Additionally, the intent to adopt technologies unique to each subpopulation in the study indicated that candidates may have been considering specific uses of technologies for their intended future student populations.
To test for heterozygote deficiency, as might result from the presence of null (nonamplifying) alleles or inadvertent pooling of subpopulations (Wahlund 1928), we tested 1 - tailed probabilities of departure from Hardy - Weinberg equilibrium, using the Markov chain exact test in GENEPOP.
We used sequence variation in the mitochondrial COI gene to ask (i) whether cyamid population structures might reveal associations among right whale individuals and subpopulations, (ii) whether the divergences of the three nominally conspecific cyamid species on North Atlantic, North Pacific, and southern right whales (Euba.laena glac.ialis, Eubal.aena jap.onica, Euba.laena aust.ralis) might indicate their times of separation, and (iii) whether the shapes of cyamid gene trees might contain information about changes in the population sizes of right whales....
PBGS members voted to reject four subpopulation estimates used in the 2015 Red List polar bear status review — even though the inclusion of those numbers was required in order for the Red List status of «vulnerable» to be upheld.
Although the VAWI was developed to assess violence primarily against women, WHO originally also planned to use it in a subpopulation of men to assess their experiences of IPV exposure.
These inconsistencies likely arise because of two reasons: (a) the literature is sparse with individual studies covering distinct time periods and examining distinct subpopulations and (b) the various studies use different operational definitions for age heterogamy (Drefahl, 2010; Rose & Benjamin, 1971; Shehan et al., 1991).
Here, we describe the research methods used in the Talking About The Smokes (TATS) project, the first ITC Project study to sample only a high smoking prevalence subpopulation within a country; in this case, Aboriginal and Torres Strait Islander peoples.
Wards with high levels of child poverty and / or high proportions of children from ethnic minorities were over-sampled to improve reliability of inference for these important subpopulations; to compensate for disproportionate stratification, sample design weights are provided with the data [18], and we used these in our analysis.
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