Sentences with phrase «subset of the cell lines»

Not exact matches

Analyzing data from thousands of cancer lines and tumors, the researchers found that those demonstrating resistance to proteasome inhibitor drugs were marked by suppressed expression of one or more of the cells» proteasome cap subunits (which are a subsets of the larger proteasome).

He adds, «This study was actually a pilot project for a much larger effort within the Center for Molecular Therapeutics to map responses against drug combinations across hundreds of cancer cell lines, not just melanoma, and look for novel combinations that will benefit subsets of patients regardless of the particular type of tumor they have.

One caveat is that the authors also observed that one of the eight human embryonic stem cell lines established following spindle transfer showed a drift in mitochondrial heteroplasmy in a subset of stem cells, despite low levels of carryover detected in the embryo.

In addition, Chk1 inhibition is highly effective as monotherapy in a subset of cancer cell lines (Thompson and Eastman, Brit J Clin Pharm 2013).