Sentences with phrase «substantial costs associated»

There are substantial costs associated with acquiring the prescription medication required after you've suffered a brain injury.

The old climate framework failed because it would have imposed substantial costs associated with climate mitigation policies on developed nations today in exchange for climate benefits far off in the future — benefits whose attributes, magnitude, timing, and distribution are not knowable with certainty.

They should also ensure all schools, regardless of type or sector, can be reimbursed for substantial costs associated regulations.

Not exact matches

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Blockchain technology can cut out the substantial intermediary costs, security risks, and record keeping infrastructure traditionally associated with such applications resulting in reduced cost, fewer time delays and less human error.

The reason for such unanimity is primarily the substantial economic costs associated with taxes on corporations, although the uncertainty as to who really pays such taxes no doubt also contributes to the disdain in which they are generally held by economists.»

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

Perinatal events can result in associated longer term health and broader societal costs, as shown by the size of damages paid in obstetric litigation cases, which represent a substantial cost to the NHS.27 Follow - up over weeks or longer to monitor recovery, or a future assessment of the outcomes for mothers and babies at a later date, would act as a vehicle for estimating costs and consequences beyond the perinatal period and shed more light on long term cost effectiveness.

«Frontotemporal degeneration is associated with substantial direct and indirect costs, diminished quality of life, and increased caregiver burden,» said James E. Galvin, M.D., M.P.H., lead author, associate dean for clinical research in FAU's Charles E. Schmidt College of Medicine, and a leading international expert on AD, Lewy Body Dementia (LBD), and FTD.

«Health care costs associated with obesity and smoking are substantial, about $ 1,360 and $ 1,046 per person per year, respectively,» said University of Illinois kinesiology and community health professor Ruopeng An, who conducted the analysis.

Sarcopenia, Greek for «poverty of flesh,» is a consistent manifestation of aging, associated with frailty, metabolic disease, cardiovascular morbidity and mortality, and substantial health care costs [200, 201].

We recognised the need to give the control back to schools and help them find supply teachers without the substantial associated costs and, likewise, for supply teachers to find work without having to forgo large portions of their salary.

One - time costs associated with starting a personalized learning school can be substantial, but not always.

More importantly, the unseen costs associated with such a strategy, the bid / offer spread for example, often increase management fees which can have a substantial detrimental impact on your overall returns, as shown in the chart on the right3.

Our debt management program offers substantial benefits without some of the costs and risks associated with debt settlement:

The costs associated with destructive, unruly, or aggressive behavior can be substantial.

«One of the shelter operations we have worked with found that they had a substantial decrease in respiratory - related feline issues and associated recovery costs when they stopped using the free clay litter that they could get and began purchasing our paper litter.»

Historically, the substantial and growing costs associated with maintaining and operating Weather West have been covered by the inclusion of web - based advertisements on the site.

As Henry points out, associate attrition rates are costing law firms substantial revenue.

«Relativity Analytics eliminated the substantial time and cost associated with reviewing the same records a second time.»

The costs associated with taking care of these injuries can be substantial.

Rigorous early case assessment is also associated with a substantial reduction in class action costs.

Since the costs associated with the class action were expected to be substantial, Copibec also requested financial assistance from the Quebec class action assistance fund (Fonds d'aide aux actions collectives), which agreed to provide financial support for the action.

Counselling and legal advice for individuals who create or donate embryos is not legally required, despite being highly encouraged or required by some clinics, and will increase the substantial costs already associated with IVF.

For insurers, costs associated with UM claims can be substantial.»

The expenses associated with buying a home can be substantial by the time you add up things such as the down payment, escrow, and other closing costs.

Generally, a cancer - specific insurance policy provides substantial cover for a whole range of costs associated with the diagnosis and treatment of cancer, including hospitalisation, chemotherapy, radiation, surgery, etc..

Now, Bank of America admits it could be forced to deal with the «substantial» costs associated with the emerging market.

The cost of raising venture capital funds or holding an IPO was a very expensive process, but an ICO opens a company to investment funding from the public without having to lose the huge percentage or pay the substantial associated fees.

• Particularly effective in roofing, repairing, re-roofing and insulating pre-installed roofs for commercial projects in a timely, organized and team oriented manner • Specialized expertise in EPDM, TPO, PVC and shingling • Skilled in carrying out maintenance and repair of mechanical, electrical and other physical structures • Well - versed in painting of structures, performing carpentry work, repairing plumbing fixtures and woodwork • Excellent physical stamina, ability to climb a ladder, bend, stoop and work in confined spaces • Special talent for metal roofing construction including flashing, wall panels, fascia and soffit • Apt at using various tools needed for cutting hammering and fastening roofing materials • Track record of completing projects in strict accordance with job specifications, project layout and applicable safety guidelines • Profound skills in installation of low sloped roof systems including TPO, BUR and bitumen • Proficient in carrying - out general roof repairs, exterior siding adjustments and HVAC installation repairs • Particularly effective in removal and installation of all types of commercial roof systems including slate, tile and asphalt • Well practiced in covering roofs with topping material including sheets, PVC and spray foam • Adept at utilizing manual and electric tools and maintaining the same in a functional order • Efficient in laying and adhering insulation with metal fasteners or binding adhesives • Expert in cutting stripes of flashing and fitting into angles formed by walls, vents and intersecting roof surfaces • Firsthand experience in carrying out regular preventive maintenance of pre-installed roofing systems • Substantial knowledge of various roofing systems and associated installation protocols • Familiar with OSHA workplace safety guidelines • Excellent listening skills with profound ability to follow verbal and written instructions to book • Great attention to detail with proven skills in interpreting and implementing given drawings and blueprints with accuracy • Strong numeracy skills, apt at generating accurate cost estimations for given projects

First, unintended pregnancy is associated with negative health consequences, including reduced use of prenatal care, lower breast - feeding rates, and poor maternal and neonatal outcomes.1, 2 Second, governments realize substantial cost savings by investing in family planning, which reduces the rate of unintended pregnancies and the costs of prenatal, delivery, postpartum, and infant care.3 Third, all Americans have the right to choose the timing and number of their children.

Recurrent delinquency is associated with high rates of multiple service utilisation and substantial societal cost.

Childhood maltreatment is associated with significantly higher rates of mortality,1 - 3 obesity,1,4 - 7 and human immunodeficiency virus infection.1, 8 Children who experience maltreatment also have significantly more mental health problems1,9 - 14 and are as much as 5 times more likely to attempt suicide.1, 15 Maltreated children are also more likely to engage in criminal behavior than other children1, 16,17 and are more than 50 % more likely to have a juvenile record than other children.17 Child maltreatment also has substantial social costs.

Protracted cases also carry substantial costs for the state and counties, including costs associated with the legal process and foster care.

A focus on early nutrition is important, as diet is a targetable risk factor; improving maternal and / or childhood diet may help lower the prevalence of early - onset conduct problems, thus lowering substantial societal and economic costs associated with childhood CP and related adjustment problems (Hsia and Belfer 2008).

Nor did it reduce the range, extent, or cost of treatment as usual: indeed the addition of developmental group psychotherapy to routine care was associated with a trend to higher costs over 12 months» follow - up (largely owing to two individuals in developmental group psychotherapy who spent substantial time in hospital or in the care of social services over follow - up — their exclusion in sensitivity analysis did not alter the main findings of the study).

«Joining with Realty Associates allows us to take advantage of the substantial population movement in and between all of our existing markets and Houston,» says Richard Haase, president of Latter & Blum, Inc. «As we diversify and grow our service area, we also lower our costs.

This saves the co-investor substantial annual expense with respect to the formation costs and annual fees associated with the single - purpose, single - member LLC.

«Joining with Realty Associates allows us to take advantage of the substantial population movement in and between all of our existing markets and Houston,» stated Richard Haase, president of Latter & Blum, Inc. «As we diversify and grow our service area, we also lower our costs.