However, in the absence of
substantial effects in the school setting, we can not ascertain effects are due to specific treatment procedures.
An obvious question is whether this underlying shock is large enough to have
substantial effects in itself, or whether the problem is mainly one of liquidity and confidence.
Already there are numerous indications of
substantial effects in response to warming of the past few decades.
The results of the Tennessee program, in contrast, look very similar to Head Start, with
substantial effects in the Head Start year but no longer - term effects.
Other supplements, such as green coffee bean extract / chlorogenic acid, white bean extract to block carbohydrate digestion, and medium - chain triglycerides have shown effects in limited trials, though I have not witnessed
substantial effects in people trying them.
Already there are numerous indications of
substantial effects in response to warming of the past few decades.
This record leaves us in no doubt that Congress may properly have considered that wheat consumed on the farm where grown, if wholly outside the scheme of regulation, would have
a substantial effect in defeating and obstructing its purpose to stimulate trade therein at increased prices.
In any case, the test was sufficiently reliable to detect
a substantial effect in favor of the Jigsaw II treatment.
Not exact matches
Thus,
in contrast with what was originally found, GVT's data reveal a
substantial, and statistically significant, hot hand
effect.
Iger also reiterated comments he has made
in the past to the
effect that if ESPN wanted to, it could come up with its own over-the-top service similar to HBO Now, and that a
substantial number of subscribers would likely pay for it.
In Marten Falls, band members are on the fence, assuming they will see
substantial economic benefits but worried about the environmental
effects of mining.
A company's leadership often plays a
substantial role
in the creation (and elimination) of workplace gossip; thus, it's largely up to employers to get rid of the negative
effects of everyday small talk.
«While the overall
effect of the 1MDB saga is hard to pin down, suffice to say that it is not something that Malaysia needs at this point, given that it already faces a number of
substantial economic challenges ahead,» echoed OCBC economist Wellian Wiranto said
in a note on Wednesday.
The
effect on Amazon has been equally significant: I detailed last year how the revelation of AWS» financial results was effectively a Facebook - level IPO, and subsequent earnings reports
in which AWS has demonstrated the power of scale — increased revenue plus increased margins — have only solidified the fact that AWS will be a
substantial driver of Amazon's revenue and (eventual!)
Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the
substantial level of government regulation over our business and the potential
effects of new laws or regulations or changes
in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation
in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger;
effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed
in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.
Although expectancy research has focused on U.S. populations, there are
substantial cultural differences
in the
effects drinkers expect / experience, extending even to symptoms of alcohol dependence (Room et al., 1996).
Companies with much greater resources than Tribune and with a
substantial head start are struggling
in a rapidly changing environment to
effect digital change that is profound enough and quick enough to overcome the outgoing tide of print revenues.
Switzerland made headlines
in the quarter when its central bank allowed the franc to float freely, but the
effect, though initially
substantial versus the euro, proved to be modest over the quarter relative to the dollar.
For iron ore and coal,
substantial increases
in contract prices are set to take
effect later this year, building on the already sharp increases of last year.
Although the
effects of a trade war would be overall
substantial, we do see a lot of variance
in our calculations.
Countries whose export bundle is concentrated
in product where no country has
substantial leverage may likely be spared from the worst
effects of a trade war.
If there is a competitive drug market, with limited advantage offered by the new drug
in terms of increased effectiveness or reduced side
effects, the drug will probably not win
substantial market share
in its product category.
Due to the
effects of market sentiment the gold price occasionally will diverge from its «true fundamentals» (as indicated by the GTFM) for up to a few months, but ALL
substantial upward and downward trends
in the gold price over the past 15 years have been consistent with the fundamental backdrop.
Raising the growth rate of the economy by 0.3 per cent (the difference between the underlying productivity growth rate
in the 1990s cycle and the average of the earlier cycles) makes little difference over a year or two; over a decade or two, however, the cumulated
effect on living standards is
substantial.
Although disasters that are particularly severe and cause
substantial resource loss can elicit greater mental health distress and PTSD symptoms, to the extent that survivors can find spiritual meaning
in such events, the deleterious
effects of disasters on mental health functioning may be reduced.
Jurisprudence
in Australia has confirmed consistently the
substantial lessening of competition test is concerned with the process of competition and not with the
effect on individual competitors.
A business with a
substantial degree of power
in a market is not allowed to engage
in conduct that has the purpose,
effect or likely
effect of substantially lessening competition
in a market.
Last year, a report by the Oxford Martin School at Oxford University, led by Professor Marco Springmann, said a tax on animal products could have a «
substantial»
effect in terms of mitigating their contributions to climate change.
«The ACCC considers that making this provision effective could be best achieved through the introduction of an
effects test, including a
substantial lessening of competition, and amendments to overcome limitations inherent
in the current interpretation of the «take advantage» test.»
Preventing firms with a
substantial degree of market power from engaging
in conduct that has the purpose or
effect of substantially lessening competition is now a central limb of Australia's competition laws.
It also requires that a corporation that already has a
substantial share of a market must not directly or indirectly merge with or acquire assets which would have the
effect or likely
effect of lessening competition
in a market.
• Where new mothers are depressed, fathers» positive parenting (self - reported) plus
substantial time spent
in caring for his infant, was found to moderate the long - term negative
effects of the mothers» depression on the child's depressed / anxious mood — but not on their aggression and other «externalising» behaviours (Mezulis et al, 2004).
As engaging with fathers around the births of their babies is the «golden opportunity moment» for intervention with them, this may have a
substantial knock - on
effect in terms of fathers» engagement with services — and
in their children's lives.
Many of the epidural side
effects mentioned below are not improved with low - dose or walking epidurals, because women using these techniques may still receive a
substantial total dose of local anesthetic, especially when continuous infusions and / or patient - controlled boluses (single large doses) are used.34 The addition of opiate drugs
in epidurals or CSEs can create further risks for the mother, such as pruritus (itching) and respiratory depression (see below).
women allocated to midwife - led continuity models of care were more likely to be attended at birth by a known midwife (RR 7.04, 95 % CI 4.48 to 11.08; participants = 6917; studies = seven); however, the
effect estimates for individual studies are highly variable, as reflected
in substantial statistical heterogeneity (Tau ² = 0.31; I ² = 94 %; Analysis 1.15).
Although professional lactation support can improve the duration of overall breast feeding, its
effect in improving exclusive breast feeding is unclear.11 18 22 Thus far, studies that report improvement of rates of exclusive breastfeeding have involved mainly community based peer counselling strategies.23 24 25 Even then, a randomised trial
in the UK recently cast doubt on the efficacy of this approach.26 There are current recommendations from NICE for the UK - wide implementation of the baby friendly initiative.4 5 6 The 2006 NICE costing report on routine postnatal care of women and their babies estimates that efforts to improve rates of breast feeding will result
in substantial cost savings for the NHS.6
Arguments
in favor of circumcision benefits indicate they outweigh the risks, have no
substantial effects on sexual function, they are low
in complications when done properly by an experienced person, and is best performed
in the neonatal period of life.
Thus even after allowing for covariates, our findings support the conclusion that breast feeding has a
substantial protective
effect against respiratory infection and illness
in the first year of life.
However, the report qualified this by saying that «
in terms of national resource use, the economic
effects of a ban on hunting would be unlikely to be
substantial», with the
effects most likely to have dissipated within a decade, but that
in the short term «the individual and local
effects would be more serious».
Another important finding from their research, however, which has attracted less media attention, is that having a history of female candidates
in a given district has a
substantial effect on the party's probability to nominate a female candidate
in the future.
This time, we achieved a
substantial majority
in favour of law making powers, meaning that, for the first time
in over 600 years, laws that
effect only Wales are made only
in Wales.
Any time a judiciary adopts procedural rules which have the
effect of violating
substantial due process rights, the said rules should ideally be disputed by the injured parties
in courts, administrative hearings, and before legislators.
Uber is going for the jugular
in the escalating Big Apple cab wars — with a
substantial drop
in prices that was scheduled to go into
effect this morning.
Finally, despite the important
effects of the
substantial rise of UKIP on the shares of the vote for the two main parties, UKIP are not set to win many seats nor have a disproportionate
effect on the competition for seats between the two main parties
in their key marginals.
But the change
in the Alberta fen was much smaller, and yet still had a
substantial effect.
Dr Meleady, a lecturer
in psychology, added: «If similar interventions were to be implemented
in comparable situations
in other cities and countries, the potential contribution to reducing air pollution, improving short and long term health, and reducing
effects of global warming could be
substantial.»
«While some characteristics of eczema
in children are the same as
in adults, our study showed
substantial differences that are important for understanding eczema
in children and developing tailored treatments that maximize effectiveness and minimize potential side
effects.»
But the positive
effect can be
substantial: Carlos Vargas - Silva of the Migration Observatory at the University of Oxford reported this year that letting
in 260,000 immigrants a year could halve the UK's public debt 50 years from now.
Sometimes, toxic side
effects aren't discovered until fairly late
in the drug development process, when
substantial amounts of time and money have already been invested
in clinical trials.
A drug with similar
effects might generate
substantial marketing... The very high heterogeneity... of
effects among trials
in the accompanying study highlights a research opportunity — to identify how to maximise the
effect.»