Sentences with phrase «substituting alanine»

To prevent the inappropriate addition of glycans, which are absent from Plasmodium proteins [31], all potential N - linked glycosylation sites (N - X - S / T, where X is not proline) were systematically mutated by substituting alanine for serine / threonine at these sites.

Any predicted N - linked glycosylation sites were systematically removed by substituting alanine for serine / threonine at these sites.

Not exact matches

Substituting those residues with alanine, which is hydrophobic, reduced lipid binding by 40-fold and stopped localization to the plasma membrane.