Here, we report a strategy for cardiomyocyte differentiation of ESCs using
substrate immobilization of insulin - like growth factor binding protein 4 (IGFBP4) with elastin - like polypeptides.
Cardiac differentiation of embryonic stem cells by
substrate immobilization of insulin - like growth factor binding protein 4 with elastin - like polypeptides.
These findings suggest that
substrate immobilization of soluble factors is a useful technique for differentiation of ESCs in regenerative medicine and tissue engineering.