Sentences with phrase «substrate of ketone body»

Further, the production of acetoacyl CoA, a substrate of ketone body formation, can occur only in the liver and thus does not apply to skeletal muscle metabolism.

Not exact matches

Emerging research (http://www.healthy-eating-politics.com/alzheimers-disease.html, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995232/) suggests a mix of glucose and ketone bodies often approaching and even exceeding 50 % as ketones may be superior to a fuel substrate made up of mostly or entirely glucose.
Ketones provided the energy substrate for our brains and bodies when glucose wasn't available, such as in times of famine which was a common occurrence for our early ancestors.
Muscles and other tissues progressively switch energy source from glucose to free fatty acids which are converted to ketone bodies (acetoacetate and b - hydroxybutyrate); these become the primary energy substrate for brain and other metabolically active tissues in the absence of adequate glucose supply.
The physiological ketosis of starvation makes sound evolutionary sense, as ketone bodies have several thermodynamic advantages over other nutritional substrates, in addition to their actions to conserve protein and glucose stores.
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