"Substrate specificity" refers to the ability of an enzyme or a chemical molecule to choose and interact with a particular type or specific group of molecules (called substrates). It means that the enzyme or molecule has a preference and can "recognize" and bind to certain substrates while ignoring others.
Full definition
Comparison of
Substrate Specificity of Escherichia Coli p - Aminobenzoyl - Glutamate Hy - drolase with Pseudomonas Carboxypeptidase G
«A conserved amino acid residue critical for product and
substrate specificity in plant triterpene synthases» is published in vol.
Insights
into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.
Separation and partial characterization of proteinases
with substrate specificity for basic amino acids from human MOLT - 4 T lymphocytes: identification of those inhibited by variable - loop - V3 peptides of HIV - 1 (human immunodeficiency virus - 1) envelope glycoprotein
We believe that our data on
NS3 substrate specificity, combined with the recent report on protein structure from other researchers, will allow for development of highly specific inhibitors in the future,» said Dr. Krzysztof Pyrć, senior author of the FEBS Letters study.
Recent studies such as ours, however, establish protein phosphatases as positive and essential regulators of signal transduction, with
remarkable substrate specificity and coordinated activities.
The protein phosphatases were too long thought to just be the negative counterpart of protein kinases, with promiscuous activity and low
intrinsic substrate specificity.
KNK168 (Ab - R - RTA), and demonstrated the mechanism of the substrate recognition and
substrate specificity of R - ATAs.
The substrate specificity of mammalian thioglycosidase involves both the aglycone and the glycosyl moieties.
When the PP2A catalytic C subunit associates with the A and B subunits several protein isoforms, namely holoenzymes, are produced with distinct activity and
substrate specificity.
Moreover, the structures of an artificial R - ATA and the G136F mutant of Ab - R - ATA (created by substituting the 136th base glycine for phenylalanine) revealed that a loop near the catalytic site was the target site that allowed the change in
substrate specificity.
Biochemical studies on telomerase for more than two decades have provided a wealth of information regarding telomerase function and
substrate specificity.
Substrate specificity of tyrosyl - DNA phosphodiesterase I (Tdp1).
Papain contains a wide array of proteolytic enzymes, incorporating a broad range of
substrate specificity and optimum environments.