Sentences with phrase «subunits containing»

Each kinesin contains two «head» subunits, and each subunit contains two binding sites — one to grip and walk along microtubules and the other to bind ATP.

Not exact matches

These results led to three conclusions about the chemical nature of ion binding sites in the conduction pathway: The channel contains two identical titratable sites, even though there are more than two (probably four) identical subunits; the sites are formed by glutamate residues that have a pKa (where K (a) is the acid constant) of 7.6; and protonation of one site does not perturb the pKa of the other.

Plasticity of mature hippocampal CA1 synapses is dependent onl - α - amino -3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate receptor A (GluR - A) subunit.

It contains five metal clusters of which clusters B, B ′, and a subunit - bridging, surface - exposed cluster D are cubane - type [4Fe - 4S] clusters.

Catalytic protein subunits of telomerase from the ciliateEuplotes aediculatus and the yeast Saccharomyces cerevisiae contain reverse transcriptase motifs.

Each subunit of the homotrimer contains a large parallel beta helix.

Consistent with recent studies of such changes, we find that long - lasting potentiation of synaptic transmission between cultured hippocampal neurons is accompanied by an increase in the number of clusters of postsynaptic glutamate receptors containing the subunit GluR1.

Recombinant p115 RhoGEF and a fusion protein containing the amino terminus of p115 had specific activity as GTPase activating proteins toward the α subunits of the G proteins G12 and G13, but not toward members of the Gs, Gi, or Gqsubfamilies of Gα proteins.

Domains that contained dilysine endoplasmic reticulum retrieval signals bound the α -, β ′ -, and ϵ - COP subunits of coatomer, whereas other p24 domains bound the β -, γ -, and ζ - COP subunits and required a phenylalanine - containing motif.

Scientists studied the gram - negative bacteria E.coli, in which the beta - barrel assembly machinery contains five subunits — known as BamA, BamB, BamC, BamD and BamE.

They determined that where a seed contained only GTP subunits, all possible subunit configurations came into existence during the growing phase and the rate of catastrophes increased with time, as seen in experiments.

Acetylcholine receptors containing the mutant subunit were about 50 times more sensitive than usual.

Researchers also knew that the composition of the receptor, which is made up of four subunits, is different in children than in adults, says Princeton University neurobiologist Joe Tsien; in children, who generally have better memories and seem to learn faster, the receptor contains more of the subunit called NR2B.

The telomerase ribonucleoprotein has a phylogenetically divergent RNA subunit, which contains a short template for telomeric DNA synthesis.

Every functional 5 - HT3 receptor must contain at least one 5 - HT3A subunit (Jackson and Yakel, 1995; Hassaine et al., 2014).

We have replaced the tobacco RbcL gene with transgenic loci containing two or three cyanobacterial genes encoding the S. elongatus Rubisco large subunit (Se LS), small subunit (Se SS) either alone or with the putative chaperone RbcX or a gene encoding the carboxysomal protein M35.

Distribution and synaptic localization of nicotinic acetylcholine receptors containing a novel α7 subunit isoform in embryonic rat cortical neurons.

Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled α6 and β3 subunits.

The restoration of the ETS structure and function was confirmed by in - gel activity assay of complex I, which demonstrated an increase in activity to 30 — 40 % of that in WT cells in cybrids transfected by constructs containing all three modifications; it was also supported by the «marked» increase in levels of COX2 and ND6, both of which are mitochondrially - encoded ETS subunit component proteins.

The addictive process fortunately appears to involve only one subtype, acetylcholine receptors containing the alpha7 subunit, making it a potential target for medications that could help smokers kick the habit.

Band - shift complementation assays show that U3A contains the E gamma subunit but does not contain an active E alpha subunit after treatment with IFN - alpha.

Induction of IL17 following S. aureus bioparticle challenge was compromised in mice lacking the ASC (Apoptosis - associated speck - like protein containing a CARD) inflammasome subunit (Figure 1G), consistent with a role for IL1β in activating IL7RαhiCcr6 + cells during the response to these bacteria.

METHODS: We treated 3T3 - L1 adipocytes with 2.5 mmol / l R (+) alpha - lipoic acid for 2 to 60 min, followed by assays of: 2 - deoxyglucose uptake; glucose transporter 1 and 4 (GLUT1 and GLUT4) subcellular localization; tyrosine phosphorylation of the insulin receptor or of the insulin receptor substrate - 1 in cell lysates; association of phosphatidylinositol 3 - kinase activity with immunoprecipitates of proteins containing phosphotyrosine or of insulin receptor substrate - 1 using a in vitro kinase assay; association of the p85 subunit of phosphatidylinositol 3 - kinase with phosphotyrosine proteins or with insulin receptor substrate - 1; and in vitro activity of immunoprecipitated Akt1.

So vaccines contain either small amounts of inactivated antigen or, more recently, subunit antigen particles that look like a virus to the body but can't really stimulate much of an immune response on their own.