Sentences with phrase «subunits form»

The researchers» models of single microtubule filaments were able to predict when and how unhydrolyzed islands of subunits form.

We found that the five subunits form a ring structure and work together to perform outer membrane protein insertion using a novel rotation and insertion mechanism.

Two tandem C - terminal regulator of K + conductance (RCK) domains from each of four channel subunits form a 350 - kilodalton gating ring at the intracellular membrane surface.

Each c subunit forms an α - helical hairpin.

The six subunits forming a hemichannel may be homomeric or heteromeric, and the hemichannels in one channel may be identical (homotypic) or not (heterotypic).

Not exact matches

In the presence of Gs alpha, the alpha subunit of the G protein that activates adenylyl cyclase, one form of adenylyl cyclase was inhibited by beta gamma, some forms were activated by beta gamma, and some forms were not affected by beta gamma.

Structures of a 10 - subunit yeast RNA polymerase II have been derived from two crystal forms at 2.8 and 3.1 angstrom resolution.

These results led to three conclusions about the chemical nature of ion binding sites in the conduction pathway: The channel contains two identical titratable sites, even though there are more than two (probably four) identical subunits; the sites are formed by glutamate residues that have a pKa (where K (a) is the acid constant) of 7.6; and protonation of one site does not perturb the pKa of the other.

The 673 - kilodalton protease complex consists of 14 copies of two different subunits, alpha and beta, forming a barrel - shaped structure of four stacked rings.

Very large aggregates can be formed from protein subunits, for example many thousand actin molecules assemble into an actin filament.

After birth, these genes are silenced and beta subunits replace them to form adult hemoglobin.

ESCRT - III subunits adopt two different conformations to form external coats that tubulate intracellular membranes.

To actually see the atomic structure of the subunit and how it forms the trimer was one of those rare «a-ha!»

There are ten different forms of α - subunits and four different forms of - subunits.

Microtubule strands assemble from subunits of alpha and beta tubulin proteins that form dimers.

Thus connected, the subunits push up through the cell membrane to form a strong, stable fiber, the team reports in the 15 November issue of Cell.

Scientists have identified 12 such subunits that can be mixed and matched to form receptors with different physiological properties.

Presenilin - 1 (PS1) or presenilin - 2 (PS2), nicastrin (NCT), anterior pharynx - defective 1 (Aph - 1), and presenilin enhancer - 2 (Pen - 2) have been considered the minimal essential subunits required to form an active γ - secretase complex.

The project focuses on the dynamics of transient microcompartments formed by the V - ATPase holoenzyme, V - ATPase subcomplexes and subunits together with the mentioned proteins, with the aim to understand the mechanisms leading to this unique type of physiologically relevant regulation.

Now a team of scientists may have found a way to stabilize Factor VIIIa in solution coaxing the subunits to form a disulfide bond — like handcuffing them together on the molecular level.

Focus of this project is the CaaX processing microcompartment transiently formed at the ER, which is required for the modification of yeast Chs4, a regulatory subunit of the chitin synthase (CHS) III complex.

Abbreviations: AGL = glycogen debranching enzyme; GSK3A / B = glycogen synthase kinase 3 α / β; GYS2 = glycogen synthase 2; PYGL = glycogen phosphorylase, liver form; PCK1 / 2 = phosphoenolpyruvate carboxykinase 1/2; FBP1 / 2 = fructose -1,6-bisphosphatase 1/2; G6PC = glucose -6-phosphatase; G6PD = glucose -6-phosphate 1 - dehydrogenase; GLUT - 2 = glucose transporter 2; INSR = insulin receptor; IRS1 / 2 = insulin receptor substrate 1/2; PIK3CA / B / D = PI3 - kinase subunit α / β / δ; and AKT1 = protein kinase B - α.

The SWI / SNF complex is polymorphic, meaning that the complex can assume different forms through various combinations of individual subunits.

Presenilins 1 and 2 (PS1 and PS2) are the catalytic subunits of the γ - secretase complex, and genes encoding mutant PS1 and PS2 variants cause familial forms of Alzheimer's disease.

Subunits alpha and beta form the catalytic core in F (1).

We postulated that UNC - 7S might rescue forward locomotion by providing a gap junction subunit in AVB hemichannels that form channels with B class motor neurons.

These subunits are linked together by peptide bonds to form chains that can be straight lines, or branched like the sub-branches on a tree.