Sentences with phrase «successful phase i trial»
Following Dr. Mendell's successful phase I trial described in the NEJM publication, additional studies to enable FDA approval of the first gene therapeutic for a fatal disease of infants are now underway.
http://www.clinicalresearchforum.org/ Not exact matches
Would you say that the phase I trial done by Acambis, based in Cambridge, U.K., and Cambridge, Mass., has been successful?
Researchers at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have developed a new radiotracer to diagnose prostate cancer and conducted a successful Phase I clinical trial.
► In a news feature in this week's Science, Ken Garber described the surprisingly, frustratingly messy path of palbociclib, one of the most promising cancer treatments to come along in years, from its conception in 1995 through its recent, successful phase - II clinical trial.
One successful compound, named Exel 647, that targets nonsmall - cell lung cancer in previously untreated patients is now in a phase 2 clinical trial.
Yong, a neuroscientist, initially had the idea to test the acne medicine in an animal model since minocycline has many anti-inflammatory properties that he thought could be useful in treating MS. Soon after obtaining successful research results, in studies also supported by the MS Society of Canada and MSSRF, Yong teamed up with Metz who led the transition into a pilot clinical trial, then a Phase 2, and finally the definitive Phase 3 trial.
In the most successful of the Phase III lymphoma clinical trials, the course of treatment consisted of seven immunizations given over 24 weeks.
In September, Alnylam Pharmaceuticals announced that its small RNA molecules silenced the gene that causes the progressive disease hereditary ATTR amyloidosis in a successful phase III trial.
In these diseases — even though it has been in clinical trials, it has not been successful, but it has gone through Phase I and Phase II safety and dosing requirements.
What are the odds that a company entering a Phase 1 trial today can see its candidate all the way through a successful Phase 3 trial?
Following successful nonhuman primate studies, Phase I safety trials in humans can begin.
Contrast this to the over 5,800 successful clinical trials using non-fetal stem cells to treat diseases that are already advancing to phase II and phase III trials.
Successful completion of the Phase 1b trial is expected to support Phase 2/3 development programs for Alzheimer's disease, as well as for Parkinson's disease.
Prothena announced the dosing of the first Phase Ia subject on April 8, 2014; they appear to have been successful in recruiting subjects and to have quickly derived favorable safety signals, as they announced the dosing of the first PD volunteer in the Phase Ib trial on July 31, 2014, «based upon safety and tolerability observed to date in the ongoing study in healthy volunteers.»
«The initiation of the NPT088 Phase 1b trial is supported by a substantial preclinical development program and the recent successful completion of a Phase 1a study in healthy volunteers.
If successful, this method will be tested at scale by an industrial partner who will generate clinical - grade material for a Phase 1 trial at the end of this five - year grant.
This successful program was the first product that reached a phase I clinical trial for LigoCyte Pharmaceutical.
If the Phase I trial proves successful, the compound must pass further stages of trial over the next few years before it becomes available to patients.
«If we are successful in this stage we would then look to start phase I clinical trials.»
Under the terms of the January 2012 agreement, Isis is responsible for global development and Biogen Idec has the option to license the compound until completion of the first successful Phase 2/3 trial.
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