Sentences with phrase «such a big impact when»

Not exact matches

Jasmine, this brought such a big smile to my face, you don't know how much of an impact it has on me when I hear that I make a positive difference in another person's life.

He struggled to make an impact with such big players and when you are playing alongside players like Fabregas comparisons often do not work in your favour.

Health improvement (allowing to post - pone / escape the diseases and thus live, healthier / disease - free longer, but not above human MLSP of around 122 years; thus these therapies do not affect epigenetic aging whatsoever, they are degenerative aging problems not regular healthy aging problem (except OncoSENS - only when you Already Have Cancer - which cancer increases epigenetic aging, but cancer removal thus does not change anything / makes no difference about what happens in the other cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to MLSP).

The fact that Kubrick's iconic films so often top best film and director polls across the media show that this his exclusion from the ranks of Best Director award holders is one of the Academy's biggest mistakes, especially when considering the films it lost out to such as My Fair Lady and One Flew Over the Cuckoo's Nest, which are well respected but not really on a par in terms of Kubrick's directorial skills, and neither George Cukor or Milos Forman have made a directorial impact elsewhere.

Beyond the conventional roles such as student government and team captains, leadership emerges when we encourage our students to take on big issues that have an impact on the world outside the classroom.

It's such a small change but really makes a big impact to your enjoyment when playing online.

Fairness does become a bigger issue when talking about other issues such as adapting to climate change impacts, but it shouldn't be the main focus for reducing emissions.

We see bailouts all the time, when companies such as banks are so big that the impact of failure would be detrimental to the economy.

Particularly when it comes to negotiating a sale contract, it's the smallest of things — such as whether minor repairs will be addressed or whether there are certain seller exclusions — that could have a big impact on price.

When I look at this room I seriously can't believe how such simple changes could make such a big impact.

I love when you can do something so cool and it does not cost that much money but has such a big impact.