Sentences with phrase «such as biofilm»

Biocellion is being used to model a variety of biological system behaviors, such as biofilm formation and wrinkling, microbial growth dynamics in complex soil structure, brain tumor growth and invasion, formation of complex bacterial colonies, and changes in blood vessels and skin cells.
Numerous studies on postmortem brains have found evidence of infection, such as biofilms, in the same regions as Alzheimer's neurodegeneration — namely, the hippocampus and temporal lobe (1).

Not exact matches

Baross at the time happened to be studying just such slime, known as a biofilm.
When P. aeruginosa infects an actual host, such as a human, it often grows as a biofilm and encounters vastly different conditions.
The finding could explain how some bacteria, such as Pseudomonas aeruginosa (P. aeruginosa), are able to thrive in oxygen - poor environments like biofilms and resist antibiotics.
Examining the effects of spaceflight on biofilm formation can provide new insights into how different factors, such as gravity, fluid dynamics and nutrient availability affect biofilm formation on Earth.
«The synthetic molecules made by our lab don't exactly look like rhamnolipids, but they can control bioactivities, such as swarming movements, surface adhesion and biofilm formation.»
These peptides can capture nonliving materials such as gold nanoparticles, incorporating them into the biofilms.
In earlier work, these investigators showed — as numerous others had done — that the messenger molecule, cyclic - di - GMP (c - di - GMP) promotes biofilm formation when such surfaces are present, said principal investigator Vincent T. Lee, Associate Professor, Department of Cell Biology and Molecular Genetics, University of Maryland, College Park.
The researchers» report appears in the journal ACS Synthetic Biology and describes development of this new type of E. coli that can even kill off slimy groups of bacteria called biofilms that are responsible for many hard - to - treat infections, such as those that take hold in the lungs, the bladder and on implanted medical devices.
First author Minyoung Kevin Kim, a graduate student in Princeton's Department of Chemistry, built experimental devices that mimicked common environments in which bacteria are subjected to the flow of liquids such as wastewater or bodily fluids: the interior surfaces of pipes, the crevices found in the lining of the intestines, and surfaces coated with biofilms, among others.
The finding could help doctors tackle infections in which biofilms are common, such as cystic fibrosis
Dental plaque may be the best - known example of a biofilm, but these slimy aggregates of bacteria also play major roles in such chronic infections as those in the urinary tract or in the lungs in cystic fibrosis patients.
But because some of the genes could indicate pathogenic characteristics — such as resistance to antibiotics — the researchers want to learn more about the potential health implications, and whether other buildings house similar biofilms.
Given the chance, the bacteria will spread across surfaces such as human tissue to form a biofilm that may resist treatment with antibiotics.
Bassler says that in some instances — such as in dental biofilms, in which some 600 species may be growing at a time — AI - 2 is necessary for collective or cooperative behavior.
This is a desirable feature for a helper drug as it would reduce the risk of treatment failure due to factors other than antibiotic resistance (e.g. biofilms, immunosuppression, etc.), allow dose reduction for toxic antibiotics such as colistin, and possibly even prevent selection of resistant mutants» says Guardabassi.
Opportunistic premise plumbing pathogens, such as the bacteria that causes Legionnaire's disease, Legionella pneumophila, can thrive in low - nutrient conditions and grow as biofilms on the inner surfaces of pipes.
Many phenotypes associated with biofilm formation and the pathogenesis of bacterial infections, for example, are secreted factors such as digestive enzymes and nutrient - chelating molecules [66].
Environmental features, such as surface chemistry and fluid flow, are also key to biofilm development.
The secretion of the matrix, together with other products such as digestive enzymes, nutrient chelators, and adhesins, provides biofilm - dwelling bacteria with increased metabolic versatility, tolerance to exogenous stress and resistance to fluid shear [9 — 15].
Biofilm formation has also been reported to be relevant for root colonization and plant protection, where bacteria (B. subtilis 6051) are able to produce antibiotic compounds (such as surfactin) that protect plants against pathogenic microorganisms (34).
Eating sugary and starchy foods, drinking tea, coffee, and soda leads to an altered pH in the mouth - > certain strains of bacteria to proliferate - > bacteria form biofilms to protect themselves from mechanical removal such as is done through the flow of saliva or brushing teeth - > biofilms cause a buildup of plaque on the teeth from bacteria in the mouth.
I read this about dissolving biofilms:» The other theoretical issue is that the biofilm may be holding on to toxic metals such as aluminum and lead.
a b c d e f g h i j k l m n o p q r s t u v w x y z