This technique has been used cautiously in managing a number of clinical indications
such as cancer therapy, genetic vaccination, and wound healing.
Not exact matches
Bellicum is among the flurry of biotechs investing heavily into cell
therapies such as experimental chimeric antigen receptor T - cell (CAR - T) treatments for
cancer (this is the next - gen treatment that involves reprogramming immune cells to become
cancer killers and has shown promise in blood
cancers, which Bellicum specializes in).
Dr. Bedient is a champion of reproductive freedom, with special interests in fertility preservation for patients undergoing toxic
therapies for medical conditions
such as cancer,
as well
as third party reproduction for same - sex couples and LGBT individuals.
During the sessions, U.S. and Cuban scientists explored
such topics
as the molecular mechanisms
cancer cells employ to evade the body's immune system, new tools to image and manipulate that system, and ways to rethink how
such therapies can best be deployed to reach patients where they receive health services.
Recent advances in the understanding of
cancer have led to more personalized
therapies,
such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to
therapy.
The type, intensity and duration of immunosuppressive
therapy contribute to the risk of developing skin
cancer,
such as melanoma, after transplantation.
For example, some
cancer treatments,
such as HER - 2 targeted
therapies, can cause weakening of the heart muscle, a condition known
as heart failure.
Tissue engineering provides a more practical means for researchers to study cell behavior,
such as cancer cell resistance to
therapy, and test new drugs or combinations of drugs to treat many diseases.
And in an ironic twist, the work could yield a new way to treat common ailments
such as heart disease and
cancer with gene
therapies.
Therefore, common treatments
such as endocrine
therapy and molecular targeting of the HER - 2 receptor are not effective for this breast
cancer subtype.
New products and developments,
such as new drugs for
cancer, fresh
therapies for rare diseases, progress in medications for HIV / AIDS, and advances in stem cell research had the greatest positive impact.
These include the ability to bring new, innovative products to the market; progress in oncology,
such as the approval of Genentech's drug Avastin for breast
cancer and advances in the use of gene
therapy, despite some setbacks; continuing progress in research on stem cells; the emergence of treatments for previously untreated diseases; and solutions for food and fuel shortages,
such as biocrops and biofuels.
Viral
therapy for childhood cancer could possibly improve if treatments such as chemotherapy do not first suppress patients» immune systems, according to findings published today in the journal Molecular Therapy — Onco
therapy for childhood
cancer could possibly improve if treatments
such as chemotherapy do not first suppress patients» immune systems, according to findings published today in the journal Molecular
Therapy — Onco
Therapy — Oncolytics.
This is crucial because
therapies,
such as cancer drugs, can target histones.
Medical researchers are talking about starting an online archive where they could post unreviewed results from clinical trials,
such as one that tested this light
therapy for
cancer patients.
«LFEX laser» enables us to generate high energy pulses of quantum beams with large current, and one can expect
such medical applications
as particle beam
cancer therapy and non-destructive inspection for bridges and etc. (or defect inspection by gamma - ray beam and neutrons).
CAM
therapies,
such as yoga and acupuncture, are becoming more common among
cancer survivors looking to improve their quality of life, and have been shown to reduce pain, fatigue, and psychological distress.
Gene
therapy can be used to neutralise harmful human genes,
such as those that cause
cancer, or to insert healthy copies of damaged genes into people with a genetic disease.
Of these variants, reported today in the journals Nature and Nature Genetics, 65 are common variants that predispose to breast
cancer and a further seven predispose specifically to oestrogen - receptor negative breast
cancer - the subset of cases that do not respond to hormonal
therapies,
such as the drug tamoxifen.
Most people live with the infection without noticeable effect, but it can be life - threatening for people with suppressed immune systems,
such as people on
cancer therapies or who have HIV / AIDS.
Because those organoids include stroma, a scaffold of connective tissue essential for tumor growth, they may prove better for studying
therapies that target the stroma,
such as cancer immunotherapy.
Natural botanical dietary supplements
such as hops have become increasingly popular among women for postmenopausal symptoms,
as they are perceived
as a safer alternative to hormone
therapy, which has been linked to increased risk of breast
cancer.
The process, which located a genetic site for the most common form of prostate
cancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer C
cancer, has potential for developing precision
therapy for other
cancers,
such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson
Cancer C
Cancer Center.
«This suggests that PGAM1 inhibitors can sensitize
cancers to PARP inhibitors
such as Olaparib, thereby expanding the benefits of PARP inhibitors to BRCA1 / 2 - proficient
cancers, particularly triple - negative breast
cancers that currently lack effective
therapies,» says author Min Huang.
Although current antiviral medicines
such as nucleos (t) ide analogue
therapy could significantly reduce liver
cancer risk, Dr. Lee notes these
therapies do not completely eliminate the risk.
This also offers the possibility to re-assess the use of vitamin K antagonists
such as warfarin in
cancer therapy,» concludes Magdalena Paolino.
«This characteristic makes gold nanorods attractive for use in catalysis, security materials and a range of biomedical applications,
such as diagnostics, imaging, and
cancer therapy,» says Joe Tracy, a materials science and engineering researcher at NC State who is senior author of a recent paper on the improved technique.
The authors conclude that FL118 - based
therapy may be beneficial for a subgroup of
cancer patients with tumors
such as chronic lymphocytic leukemia and melanomas, in which MdmX overexpression confers treatment resistance.
And pinpointing a genetic signature,
such as EGFR mutations in lung
cancer or HER2 mutations in breast
cancer, can guide
therapy decisions.
During the past decade, some
cancer research has highlighted the potential
therapies found in plants, including chemicals found in foods
such as turmeric, apple peels and green tea.
The new findings could be used to inform precision - medicine approaches that help minimize a person's risk for common diseases —
such as diabetes, cardiovascular disease and
cancer — by tailoring diet - based prevention and
therapy to the specific needs of an individual.
Gene
therapy within the next decade or so is not going to prove very effective in eliminating solid
cancers such as lung, breast, prostate, colon and so on.
Standard treatments for ER + breast
cancer are endocrine
therapies such as tamoxifen and aromatase inhibitors.
This promises to make proton
therapy an option for thousands more
cancer patients by reducing the risks of healthy tissue being damaged during treatment, particularly in vulnerable parts of the body
such as the brain, eye and spinal cord.
There are now more than 100 gene
therapy clinical trials aimed toward
cancer, genetic diseases (
such as ADA deficiency, cystic fibrosis and hemophilia A), infectious diseases (including AIDS) and autoimmune diseases (
such as rheumatoid arthritis).
Hot flashes are particularly severe and frequent in breast
cancer survivors, but current FDA - approved remedies for these unpleasant episodes,
such as hormone replacement
therapies are off - limits to breast
cancer survivors because they include estrogen.
«Also, we believe that anti-CtBP
therapies such as HIPP may be able to complement current
therapies to counter drug resistance and decrease metastasis, ultimately increasing our ability to control and cure colon
cancer.»
As such, macrophage - based
cancer therapies were investigated decades ago.
Because diseases
such as cancer tend to evade detection by T - cells» receptors, allowing a tumor to grow unchecked, scientists have long sought «intel» on this process
as a means of developing
therapies that target malignant cells, but leave healthy cells alone.
Richards describes how the adoption of some of the standard
cancer therapies,
such as 5 - Fluorouracil and Interferon, was not based on their passing the validity test Moertel and his colleagues had insisted upon in the case of vitamin C.
«Current
therapies take advantage of this by using targeted drugs
such as Trastuzumab or Lapatinib to specifically inhibit ERBB2, but eventually they become ineffective
as the
cancer develops resistance to those drugs.»
Current
therapies for autoimmune disease,
such as prednisone and rituximab, suppress large parts of the immune system, leaving patients vulnerable to potentially fatal opportunistic infections and
cancers.
According to Sinclair, all of the mammalian SIRT genes (and their proteins) are possible drug targets for
therapies aimed at extending life,
as well
as staving off age - related illnesses,
such as Alzheimer's disease,
cancers and metabolic disorders, like diabetes.
This is the first population - based study to compare the follow - up intensity of American men with prostate
cancer who have not undergone aggressive treatment with those who opted to undergo various forms of aggressive
therapy,
such as surgery and radiation.
This complexity contributes to its aggressive nature and resistance to conventional
therapies such as chemotherapy and radiation
therapy,» says Fisher, Thelma Newmeyer Corman Endowed Chair in
Cancer Research and co-leader of the
Cancer Molecular Genetics research program at Massey
Cancer Center, professor and chair of the Department of Human and Molecular Genetics at the VCU School of Medicine, and director of the VIMM.
Management of low risk prostate
cancer with
AS appears feasible and safe, yet most men in the U.S. with low risk disease still undergo definitive therapies such as radical prostatectomy, which carry the burden of urinary, bowel, and sexual dysfunction that can be avoided, or at the very least postponed, with management on A
AS appears feasible and safe, yet most men in the U.S. with low risk disease still undergo definitive
therapies such as radical prostatectomy, which carry the burden of urinary, bowel, and sexual dysfunction that can be avoided, or at the very least postponed, with management on A
as radical prostatectomy, which carry the burden of urinary, bowel, and sexual dysfunction that can be avoided, or at the very least postponed, with management on
ASAS.
Technology
such as this, scientists said, may have a promising future in the identification and surgical removal of malignant tumors,
as well
as using near - infrared light
therapies that can kill remaining
cancer cells, both by mild heating of them and generating reactive oxygen species that can also kill them.
TNBC is deadly because, unlike other types of breast
cancers such as estrogen receptor (ER) positive or HER2 amplified breast tumours which have effective targeted
therapy, TNBC tumours do not respond to targeted
therapy.
The total radiation delivered, 0.5 gray (Gy), was high relative to environmental levels (from sources
such as naturally occurring radon in rock), but significantly lower than equivalent human doses experienced in CAT - scans or
cancer therapy.
Since the initial discovery of EGFR mutations in lung
cancer 10 years ago, EGFR targeted
therapies such as erlotinib (Tarceva) and afatinib (Gilotrif) have become a fundamental component of lung
cancer therapy.