Not exact matches
Benedict argued that non-conjugal reproduction
such as in vitro fertilization had created «new problems» ¯ the freezing of human embryos, for instance, and the selective abortion of medically implanted embryos, together with pre-implantation diagnosis,
embryonic stem -
cell research, and attempts at human cloning.
The NIH defines totipotent
cells as the source of both
embryonic stem cells and of trophoblast
cells which give rise to extra-
embryonic tissues
such as the placenta.
research; since most of the reports have concentrated on justifying the creation of cloned human embryos for research into and treatment of neurodegenerative diseases
such as Parkinson's, «
stem -
cells» has become synonymous with «
embryonic stem -
cells» in the public imagination.
Embryonic stem cells are produced during development by the same process of epigenetic programming that later will produce adult
cells such as skin and brain.
(i) a woman's right to an abortion; (iii) medical immunization of teen girls (and boys) against HPV; (iv) assisted suicide; (vi) gay marriage; (vii) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» Catholics; (viii) basic $ ex education for older school children; (ix) treating drug abuse
as principally a medical issue; (x) population control; (xi) buying alcohol on a Sunday in many places; (xii) use of condoms and other contraceptives; (xiii)
embryonic stem cell research; (xiv) little 10 year - old boys joining organizations
such as the Boy Scouts of America, regardless of the religious views of their parents; and (xv) gays being allowed to serve openly in the military.
On Thursday, the United Nations» member states will consider two resolutions: One resolution would ban all human cloning methods, including efforts to use cloned
embryonic stem cells to try and generate healthy tissues, or to treat degenerative diseases
such as Parkinson's.
Human
embryonic stem cells are at last being tested in common, potentially fatal diseases
such as heart failure and diabetes
Although the U.S. government puts stringent restrictions on funding for research on
embryonic stem cells, individual states
such as California have set up institutes to perform that work and general
stem cell studies.
Using a mathematical model known
as the Ising model, invented to describe phase transitions in statistical physics,
such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human
cell types, including normal and cancerous colon, lung and liver
cells,
as well
as brain, skin, blood and
embryonic stem cells.
In 2006, Japanese scientists figured out how to reprogram specialized
cells,
such as those in skin, so that they act like
embryonic stem cells.
The act of reprogramming
cells to make them
as capable
as ones from embryos apparently can result in aberrant
cells that age and die abnormally, suggesting there is a long way to go to prove
such cells are really like
embryonic stem cells and can find use in therapies.
Embryonic stem cells helped researchers develop other research tools,
such as iPSCs, he pointed out.
Contributions from careful, sober - minded scientists can also help defuse controversy in fields that get headlines,
such as climate change and
embryonic stem cells.
In this way they act like
embryonic stem cells and share their revolutionary therapeutic potential — and
as such, they could eliminate the need for using and then destroying human embryos.
In the last few years, researchers have learned how to turn
embryonic stem cells into all sorts of different
cell types,
such as skin
cells, heart
Although
embryonic stem cells are naturally pluripotent, iPS
cells are created by scientists from existing adult
cells,
such as skin or blood.
There is evidence that chronic disabilities
such as spinal cord lesions, diabetes, and Parkinson?s disease, where replacement of just one
cell type restores tissue function, can be treated with differentiated
embryonic stem cells.
Pluripotent
stem cells include
embryonic stem cells, which are derived from early embryos, and induced pluripotent
stem cells, which are made by reprogramming
cells taken from adult tissues
such as skin.
Not only do many of the ethical challenges posed by
embryonic stem cells remain, but the relative ease and low cost of iPS techniques, combined with the accessibility of
cells, accelerate the need to address futuristic - sounding possibilities
such as creating gametes for reproduction.
He has guided us through
such issues
as the organ donor market (he opposed the sale of kidneys to the highest bidder), the Terri Schiavo case (he opposed government intervention to keep her alive), and the
stem cell wars (he supports
embryonic stem cell research).
hESC researchers George Daley of Children's Hospital Boston and Sean Morrison of the University of Michigan told the panel why research on other types of
stem cells,
such as adult
stem cells and so - called induced pluripotent
stem cells (iPSCs), can't substitute for work on
embryonic cells.
«Researchers are just now figuring out how adult somatic
cells such as skin
cells can be turned into
embryonic stem cells.
Embryonic stem cells have the potential to develop into any
cell type in the body, and many scientists would like to discover how to use them to treat intractable diseases
such as diabetes or Parkinson's disease.
Neural crest
cells are a type of
stem cell; during vertebrate
embryonic development, they eventually differentiate into specialized
cells such as those that make facial skeleton
cells or those that create pigment
cells.
Human
embryonic stem cells derived from affected embryos during a pre-implantation diagnostic (PGD),
as well
as the conversion of somatic
cells,
such as skin fibroblasts, into induced pluripotent
stem cells by genetic manipulation, offer the unique opportunity to have access to a large spectrum of disease - specific
cell models.
Benedict argued that non-conjugal reproduction
such as in vitro fertilization had created «new problems» ¯ the freezing of human embryos, for instance, and the selective abortion of medically implanted embryos, together with pre-implantation diagnosis,
embryonic stem -
cell research, and attempts at human cloning.
Yamanaka and Takahashi began their search by studying
embryonic stem cells in the hope of identifying the genes that underlie essential
stem cell characteristics,
such as pluripotency and proliferation, a
cell's ability to replicate itself.
Pluripotent
cells such as embryonic stem (ES) and induced pluripotent
stem (iPS)
cells are the starting point from which to generate organ specific
cell types.
Current efforts, mostly conducted in animal models, involve attempting to derive and aggregate
embryonic stem cells, exposing them to
such factors
as acetic acid, allowing them to differentiate, or specialize, and then sorting through these
cells to extract the
cell types of interest.
When derived from fetal membranes,
such as chorionic and amniotic membranes, MSCs are considered an intermediate between human
embryonic stem cells (hESCs) and adult
stem cells.
Human pluripotent
stem cells (hPSCs), including human
embryonic stem cells (hESCs) and human induced pluripotent
stem cells (hiPSCs), are known to be vulnerable to apoptosis upon various technical manipulation,
such as single
cell dissociation, freezing and thawing, etc., which hinder their use for clonal isolation in gene transfer, differentiation and FACS
cell sorting.
Such an immunological exemption could alleviate many concerns about using cells for therapy that don't exactly match the recipient's immune system - such as existing embryonic stem cell lines that are not directly derived from the recipi
Such an immunological exemption could alleviate many concerns about using
cells for therapy that don't exactly match the recipient's immune system -
such as existing embryonic stem cell lines that are not directly derived from the recipi
such as existing
embryonic stem cell lines that are not directly derived from the recipient.
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibil
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human
embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibil
stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control
such things
as individual traits and disease susceptibility.
Other bodies,
such as GTAC and the MHRA, will then be involved in the regulation of any clinical trials involving either
embryonic or fetal
stem cells.»
She argues that early research into
embryonic stem cells have shown them to be largely unhelpful, while research using adult
stem cells has cured or improved the outcome for
such diseases
as lupus and multiple sclerosis.
As one example, using insights from
embryonic development, Jessell has been able to convert
embryonic stem cells into functioning motor neurons, facilitating the discovery of medicines to treat
such diseases.
AST - OPC1, an oligodendrocyte progenitor
cell population derived from human
embryonic stem cells, has been shown in preclinical testing in animals and in vitro to have three potentially reparative functions that address the complex pathologies observed in demyelination disorders,
such as spinal cord injuries, and multiple neurodegenerative diseases, including multiple sclerosis and white matter stroke.
Embryonic stem cells with identical genomes grow into distinctive tissues,
such as heart, bone, and brain.
«This discovery will advance our understanding of
stem cell epigenetics and chromatin structures, provide potential mechanisms on maintaining the hallmark properties of ES
cells, and help researchers with the rich source of information to better understand some of the unique features —
such as self - renewal and pluripotency — of human
embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member of the Singapore team that conducted this research.
InvivoSciences makes engineered heart tissues from mouse
embryonic stem cells and
stem cells from differentiated adult tissues in humans,
such as fat and skin.
Various
cell types have been examined for use in RPE
cell replacement including immortalized
cell lines,
such as the human RPE
cell line, ARPE19 [2], sheets of adult RPE [3], foetal RPE [4], RPE derived from human
embryonic stem cells (HESC - RPE)[5]--[10] and many non-RPE
cells lines [11]--[15].
Patient - specific
stem cells may offer an alternative to
embryonic stem cells that will skirt the need for immunosuppressive therapy
as well
as the social and political ramifications of
embryonic stem cell research, but their utility extends far beyond
such groundbreaking advances and will assist future clinical practice and patient care.
• Despite the fact that U.S. scientists were the first to derive human
embryonic stem cells, leadership in this area of research is shifting to other countries
such as the United Kingdom, Singapore, South Korea, and Australia.
Many states,
such as California, are pushing forward public funding for the rapidly growing field of research while Michigan has outlawed
embryonic stem cell research.
Studies have identified transcription factors
such as Stat3, Nanog, and Oct4
as being necessary for
embryonic stem (ES)
cell self - renewal and maintenance of pluripotency.
As you know, embryonic stem cells have the potential to be used to treat and better understand deadly and disabling diseases and conditions that affect more than 100 million Americans, such as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many other
As you know,
embryonic stem cells have the potential to be used to treat and better understand deadly and disabling diseases and conditions that affect more than 100 million Americans,
such as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many other
as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many others.
Without these two technologies that you'll hear about in a moment, there would be no
such thing
as human
embryonic stem cell research, and President Bush could have enjoyed his summer vacation in Crawford without having to agonize over the baptism of the infamous 64
stem cell lines.
* The role of the US in global efforts to address pollutants that are broadly dispersed across national borders,
such as greenhouse gasses, persistent organic pollutants, ozone, etc...; * How they view a president's ability to influence national science policy in a way that will persist beyond their term (s),
as would be necessary for example to address global climate change or enhancement of science education nationwide; * Their perspective on the relative roles that scientific knowledge, ethics, economics, and faith should play in resolving debates over
embryonic stem cell research, evolution education, human population growth, etc... * What specific steps they would take to prevent the introduction of political or economic bias in the dissemination and use of scientific knowledge; * (and many more...)