Sentences with phrase «such early onset»

This is the first time that this apparent influence has been demonstrated for observed father - infant interaction and such early onset behaviour problems.

Not exact matches

Most women don't understand that the incidence of endocrine disruptive disorders such as endometriosis, fibroids, polycystic ovarian syndrome, infertility, early onset puberty, early onset menopause, heavy, painful and prolonged periods and breast cancer are mainly caused by the endocrine disruptive chemicals found in skin, hair, beauty and personal products.

But in essence, the same molecular mechanisms may account for the delayed age of onset of illnesses, such as schizophrenia, in early adulthood, says Dr. Petronis.

Deciphering the onset time can impact how the doctor treats the woman's depression, such as intervening earlier with psychiatric help, if needed, said Sheehan Fisher, the study's corresponding author and an instructor of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine.

Mutations that detrimentally affect the function of neuronal KV7 channels cause hyperexcitability syndromes such as benign familial neonatal seizures, early onset epileptic encephalopathy, and peripheral nerve hyperexcitability.

Such biomarkers raise the possibility of early diagnosis, since levels of certain compounds differ between healthy people and patients with NPC, even before the onset of symptoms.

Many suspect this inflammation drives the early onset of aging - related conditions such as dementia and cardiovascular disease.

Albertini replied that there might be subtle health effects, such as early onset of adult diseases like diabetes and cancer, that won't appear until 15 or 20 years after IVF, and he pointed out that there is very little follow - up data on the health of children created through assisted reproductive medicine.

Having shorter telomeres is connected to the early onset of illnesses such as cardiovascular disease and cancer, with mortality in older adults and, as CMU's Sheldon Cohen first discovered, predicts susceptibility to acute infectious disease in young to midlife adults.

Dr. Romero emphasized that the cost of preeclampsia goes beyond the short - term health care expenditures as women affected by this disorder are at an increased risk for early onset cardiovascular diseases, such as heart attacks and hypertension, years and decades after delivery.

Our approach differs from that adopted by Charlesworth [61], [62], who developed mathematical models to formalize the mutation accumulation hypothesis [63] that, together with the antagonistic pleiotropy hypothesis [3], [64], may be used to show how senescence can evolve by the accumulation of deleterious alleles through mutation - selection balance at frequencies that increase with their age of onset; such mutations enhance reproductive performance early in life but diminish survival late in life through physiological trade - offs.

It is important to understand pubertal timing as early pubertal onset can influence the risk of developing a number of health disorders such as obesity and diabetes in adulthood.

This can be caused by a number of spinal deformities such as congenital scoliosis, missing ribs, fused ribs, deformed vertebrae, or other types of severe early onset scoliosis.

Following a period of intensive meditation, genes involved with the infectious cycle may get downregulated along with related host genes regulating protein synthesis, an explanation that is supported by other stress reduction interventions that have shown increased innate antiviral activity, such as upregulated Type 1 interferon activity.40 Shorter telomeres in population - based studies have been predictive of earlier onset of chronic diseases of aging, including diabetes, 41 cardiovascular disease9 and certain cancers.42

The least severe can be risk factors for early adult - onset degenerative diseases, such as osteoporosis and osteoarthritis.

Does there seem to be an excess of other cancers as well as melanoma such as sarcoma, early onset of breast cancer, brain tumours or pancreatic cancer?

17 / Jun / 2013 Although a family history of Alzheimer's disease is a primary risk factor for the devastating neurological disorder, mutations in only three genes — the amyloid precursor protein and presenilins 1 and 2 — have been established as causative for inherited, early - onset Alzheimer's, accounting for about half of such cases.

According to Parkinson's Victoria, a person diagnosed with early onset Parkinson's, is likely to experience symptoms such as:

Endocrine disruptors have also been linked to conditions such as male infertility (Male Fertility and Diet and Xenoestrogens and Sperm Counts) and early onset of puberty (Protein, Puberty, and Pollutants and Xenoestrogens and Early Pubeearly onset of puberty (Protein, Puberty, and Pollutants and Xenoestrogens and Early PubeEarly Puberty).

Endocrine disruptors have also been linked to conditions such as male infertility (see Male Fertility and Diet and Xenoestrogens and Sperm Counts) and the early onset of puberty (Protein, Puberty, & Pollutants and Xenoestrogens & Early Pubeearly onset of puberty (Protein, Puberty, & Pollutants and Xenoestrogens & Early PubeEarly Puberty).

This helps mitigate patient's underlying genetic risk, which may help prevent the early onset of conditions, such as cardiovascular disease.

The typical lifespan of a Japanese Chin is 10 — 12 years, and they suffer from fairly common genetic diseases such as patellar luxation, cataracts, and early - onset heart murmurs.

The disease is characterized by early onset muscular problems such as awkward gait, fatigue, and difficulty eating.

Among the most common problems are early - onset heart murmurs, eye problems such as retinal dysplasia and cataracts, and luxating patellas (slipping knees).

But when they eat only (or primarily) dry foods, cats can develop problems such as bladder stones, bladder irritation or cystitis, constipation and early - onset kidney disease.

Also, be aware that non-surgical approaches have consequences such as earlier onset of arthritis, limited range of motion and less functionality.

«Pet obesity significantly increases the danger of developing major health problems such as diabetes, arthritis and heart disease and can also bring about the onset of these chronic diseases much earlier.

Treatment, if provided early and prior to onset of severe conditions such as hepatic encephalopathy or ketoacidosis, is effective.

Similarities between canine compulsive behaviours and their human analogues include repetitive nature, early - onset and response to medication such as serotonin reuptake inhibitors (SSRIs).

In conclusion, the early - onset and the variable nature of the repetitive behaviour, which is affected by environmental factors such as micronutrients, neutering and maternal care, share several similar components between canine and human compulsions and supports canine TC as a model for human OCD.

Two studies have identified groups of girls exhibiting chronically high levels of antisocial behavior across childhood and early adolescence and having an increased risk for continued antisocial behavior.60 In addition, Odgers and several colleagues found that 7.5 percent of all girls between the ages of seven and fifteen displayed an early - onset of offending that persisted into adolescence and that this pattern was similar to boys of the same age.61 Other studies suggest that although strongly aggressive behavior in girls before the age of seven is rare, continuity of offending for such girls may be stronger than that among comparable boys and that such early problem behavior in girls should be considered a significant warning sign of potential future problems.62

A question for future research is whether risk factors exert their effects for only a limited period (suggesting that the same risk factors we measured in early childhood, such as losing a parent, would predict adult - onset MDD if they occurred in late adolescence) or whether risk factors are developmentally sensitive, and those that predict juvenile - onset MDD are qualitatively different from those that predict adult - onset MDD.

However, depressed children and adolescents may also experience unique psychosocial risks, such as poor parenting or family discord, especially if these risks are genetically mediated.10, 11 Additional support for the hypothesis that juvenile - and adult - onset MDD are distinct subtypes would be demonstrated if early childhood psychosocial risks were differentially associated with juvenile vs adult - onset MDD.

In the case of low childhood SES, chronic exposure to such stressors as financial hardship, threat of violence, violence exposure, family turmoil, and instability in parental employment may confer an underlying risk profile that remains in latent form until adulthood, when early onset chronic diseases may begin to appear (13).

Rather fewer meet the diagnostic criteria for research, which for the oppositional defiant type of conduct disorder seen in younger children require at least four specific behaviours to be present.7 The early onset pattern — typically beginning at the age of 2 or 3 years — is associated with comorbid psychopathology such as hyperactivity and emotional problems, language disorders, neuropsychological deficits such as poor attention and lower IQ, high heritability, 8 and lifelong antisocial behaviour.9 In contrast, teenage onset antisocial behaviour is not associated with other disorders or neuropsychological deficits, is more environmentally determined than inherited, and tends not to persist into adulthood.9

The first year of life is a period of rapid development critical to infants» health, emotional well - being and developmental trajectories.1, 2 The first signs of mental health problems are often exhibited during infancy; however, the symptoms may be overlooked by parents and healthcare providers because they can be less intrusive when a child is young.3 — 8 Early onset of emotional or behavioural problems increases the risk of numerous adverse outcomes that persist into adolescence and adulthood, such as delinquency, violence, substance abuse, mental health problems, teen pregnancies, school dropout and long - term unemployment.1, 2, 4, 9 — 14

It has been long known that there is an early - onset group of boys whose multiple mental health problems, such as noncompliant and aggressive behaviors, are manifest in childhood (Farrington et al. 1990; Loeber and Farrington 2001).

Children with early onset of either internalizing problems such as anxiousness and withdrawn behavior (e.g., [4]-RRB- or persistent externalizing problems such as defiant and disruptive behavior (e.g., [5 — 7]-RRB- are also at higher risk for continued severe and debilitating mental health problems during adolescence and adulthood [8, 9].

Not only can symptoms be distressing, AUD can trigger a cascade of lifelong adverse outcomes, such as: other mental disorders, suicide, serious unintentional injury, illicit drug use, antisocial behaviour, as well as early onset of heart disease, stroke and cancer.3 While the peak age for the onset for AUD is 18 — 24 years, the factors that predict the transition from alcohol use to AUD symptom onset and from symptom onset to diagnosable AUD remain largely unknown.

This pathway is characterized by three elements: the onset of conduct problems (such as developmentally excessive levels of aggression, noncompliance, and other oppositional behaviour) in the preschool and early school - age years; a high degree of continuity throughout childhood and into adolescence and adulthood; and a poor prognosis.1, 2 The most comprehensive family - based formulation for the early - starter pathway has been the coercion model developed by Patterson and his colleagues.3, 4 The model describes a process of «basic training» in conduct - problem behaviours that occurs in the context of an escalating cycle of coercive parent - child interactions in the home, beginning prior to school entry.

The inability to make advantageous decisions under conditions of risk is associated with health - risk behaviors such as early - onset alcohol and drug use.

Some specifiers, such as CU traits (or LPE DSM - 5 specifier), as well as early age of onset of symptoms and comorbidities, should promote more timely referrals, assessments, and possibly an intensive treatment, and follow - ups.

We omitted cases in which maternal depression had not occurred prior to child age 5 years in children who had nondepressive early disorders, but retained cases can not precisely determine that maternal depression occured prior to youth onset of disorders such as attention - deficit / hyperactivity disorder.

The resulting stress trajectories may include the early onset of puberty (Ge et al. 2001), adolescent stressful life events and circumstances (Wickrama et al. 2015b), romantic relationship problems (Barr et al. 2016), and an off - time (early or late) transition to adulthood, including the acquisition of adult roles such as becoming a parent, cohabiting, and dropping out of school (Lee 2015; Wickrama et al. 2015a, 2005).

Previous research has suggested that parental and child functioning factors are the most significant predictors of early onset risk behavior (i.e., prior to adolescence), as opposed to more distal factors such as the neighborhood environment and social status among peers (Kaplow et al. 2002).

Infant mental health researchers have identified another subgroup of children with the onset of psychopathology (with or without environmental triggers), highlighting an early predisposition to partial or full psychiatric disorders such as disruptive behavior or anxiety disorders.

The onset and persistence of conduct problems is important, as the earlier the onset, the greater the (a) co-morbidity of adjustment problems, such as emotional difficulties and hyperactivity, and the (b) risk for a life - course trajectory of antisocial behaviour and lifestyle (Moffitt 2006).