Sentences with phrase «such gene circuit»

Not exact matches

We're funding researchers to investigate how drugs alter what genes are activated such that they modify the function of the cells, and how this, in turn, modifies the functions of brain circuits, and how that modifies behavior.

These two gene families likely allowed the octopus to build unique neural circuits serving functions such as memory, navigation and planning.

If a potential mate diverges from the standard in a way that more optimally excites «species - identifying» brain circuits, the genes that promote such supertraits will flood the population.

Also, most DIY biologists are interested in building genetic circuits in bacteria or yeast, and they can generally do this using well - established techniques, such as SLiCE (seamless ligation cloning extract), and with genes that have been synthesized by commercial suppliers or that can be obtained from the iGEM registry.

However, despite how important mate choice is, the genes, cells, and circuits that are required to make such a decision remain largely unknown.

The vectors are customizable and could potentially be used as part of a gene therapy to treat neurodegenerative disorders that affect the entire central nervous system, such as Huntington's disease, or to help map or modulate neuronal circuits and understand how they change during disease.

«For our new systemic viral vectors — AAV PHP.S and AAV PHP.eB — there are many potential uses, from mapping circuits in the periphery and fast screening of gene regulatory elements to genome editing with powerful tools such as CRISPR - Cas9,» says Gradinaru.

Feng's group is focusing first on conditions with the strongest human genetic data, such as Huntington's disease, in which a single gene causes a disorder, and using advanced neuroimaging technology and other tools to understand how the mutation causes brain circuits to misfire.