Sentences with phrase «such gene inactivation»
A quirk of the physiology of C. elegans means that such gene inactivation can occur simply if the RNAi molecule is eaten by the worm.
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Extending these results into rodent models of H. pylori - induced inflammation and carcinogenesis (Mongolian gerbils and mice), we have shown that inactivation of such genes attenuates the development gastric injury and cancer.
CELPHEDIA with the partners of PHENOMIN (ICS, TAAM, CIPHE), the National Infrastructure for Mouse Phenogenomics, is committed in international consortia, such as IMPC «International Mouse Phenotyping Consortium» whose goal is to create the functional encyclopedia of the mouse genome by achieving inactivation mutants of every mouse gene and by performing their exhaustive phenotyping for all major physiological functions.
The SKIP - e bioinformatics system has been developed to assist researchers in selecting antisense oligonucleotides that can be used as therapeutic agents to restore the production of a functional deleted protein such as for DMD or as tools to study gene function through the inactivation of a protein through nonsense mediated decay.