Sentences with phrase «such immune attack»

«This study breaks new ground because it focuses on boosting beta cell performance and shows that beta cell preservation is possible even in the face of such immune attack,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and J.S. Simmons Professor of Genetics and Metabolism at HSPH.

Not exact matches

But there is little basis for assuming that he has not made such modification because he believes his position is «privileged» and thus immune from attack.

Health benefits: Sweet potatoes are loaded with essential vitamins and minerals like vitamins C, B6 and D, which help promote overall health, prevent such serious health risks as heart attacks and bone decay, and also ensure proper immune system function.

The systemic problem, (i.e. combining an erroneous outcome with the supposition of it being absolutely dependent on hacking), would be that such a feeble response of a national immune system to relatively trifling attacks implies a nation prone to infections.

For unknown reasons our immune system attacks healthy cells, tissues and organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.

Typically, when the body senses a foreign substance such as a virus or a bacterium, it sends immune cells to attack the invader while also bolstering the immune system as a whole.

When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop «T cell exhaustion,» becoming less effective and losing their ability to attack and destroy the invaders of the body.

Normally, the immune system protects the body by attacking foreign invaders such as viruses, bacteria and other pathogens.

A DNA vaccine's tolerizing effect could potentially be used to combat autoimmune diseases — such as some forms of diabetes and arthritis — in which the immune system attacks and destroys its own tissues.

In the malady, a victim's immune system attacks hormone - producing organs such as the pancreas and the thyroid, parathyroid, and adrenal glands, often rendering them nonfunctional.

The immune system normally produces antibodies to attack foreign substances in the body, such as bacteria.

SjS is an immune mediated chronic inflammatory disease where the body's immune system attacks glands that secrete fluid, such as the tear and saliva glands.

Although some cancers — particularly those that are rife with mutations like lung cancer or melanoma — create more tangible targets on the surface of cells for the immune system to recognize and attack, other malignancies such as prostate and pancreatic cancers have proved more intransigent.

Enhancing such an interaction, perhaps in combination with other therapies that attack the virus at other stages of its life cycle, could give the immune system the opening it needs to overcome an infection.

Orchestrating a successful immune attack against tumors has proven difficult so far, but a new study from MIT suggests that such therapies could be improved by simultaneously activating both arms of the immune system.

However, in several chronic human diseases such as inflammatory bowel disease (IBD), HIV / AIDS, cancer, cardiovascular disease, and diabetes, the immune system attacks these normally beneficial bacteria, resulting in chronic inflammation and contributing to disease progression.

As such, scientists hypothesise that cathelicidins may be involved in the control of type 1 diabetes, an autoimmune disease where certain cells in the immune system attack beta cells in the pancreas which secrete insulin.

These immune cells, which are supposed to fight intruders such as bacteria, take a wrong turn and start attacking the recipient's already weakened body.

Kwak has developed anti-cancer therapeutic vaccines to spark an immune system attack against tumors, but their effectiveness has been hindered by factors such as MDSCs that stifle immune response.

Vitamin D is thought to protect against such attacks by boosting immune responses to respiratory viruses and dampening down harmful airway inflammation.

Scientists have theorized that under the right conditions, such bacteria burrow their way into the gut lining, inciting immune cells to attack and harm the intestine.

Once they identified this pathway, Hanks and colleagues conducted laboratory tests of a molecule that blocks melanoma cells from going stealth, enabling the immune system to mount a direct attack while also enhancing the function of current immunotherapies such as pembrolizumab and nivolumab.

It's uncertain whether other cell types, such as the immune cells that enter the lungs after an attack, have adenosine receptors — and scientists don't even know the source of the adenosine.

Following a tissue graft transplant — such as that of the face, hand, arm or leg — it is standard for doctors to immediately give transplant recipients immunosuppressant drugs to prevent their body's immune system from rejecting and attacking the new body part.

Examples include: the co-evolution of flowering plants and pollinators such as bees, lizards and moths; pocket gophers and their lice; humans and intestinal microbes; and the war our immune systems wage with the pathogens that attack us.

Unlike foreign intruders such as bacteria, tumor cells are the patient's own and hence are less viciously attacked by the immune system.

He further showed that PD - L1 is highly expressed on many solid tumors such as breast and lung, as well as some hematologic malignancies, and allows these tumors to resist immune attack.

Your immune response to the virus can trigger a crisis such as a heart attack or even spiral out of control and kill you.

When Interleukin - 12 is produced in the tumor, immune cells are stimulated locally in such a manner that the tumor is attacked and rejected.

Such T cells are key to preventing the immune system from attacking the body in autoimmune disease.

An alternative approach is to persuade the immune system to attack tumours, using vaccines, biological therapies such as alpha interferon or interleukin 2 and genetically altered white blood cells.

They also assist in the prevention of autoimmune diseases, such as diabetes (an immune attack on the pancreas) and multiple sclerosis (an immune attack on the nerves).

Frustratingly, cancer cells have evolved their own ways to defend from immune attack, such as dressing up in molecules that form an invisibility cloak.

Autoimmune diseases such as rheumatoid arthritis and type 1 diabetes result when the body's immune system mistakenly attacks its own tissue.

GVHD is an immune - mediated disease in which donor T cells recognize and attack the histocompatibility - disparate recipient; it involves multiple organs, such as the lung, liver, intestinal tract, and skin (2 — 4).

Bordenstein theorizes that when a wasp, such as a hybrid, plays host to the wrong microbes, the wasp's immune system may attack and kill itself instead of foreign pathogens.

An important area of research focus for NIAID is the immune system, the complex network of cells, tissues, and organs that work together to defend the body against attacks by foreign invaders such as bacteria, viruses, parasites, and fungi.

He is particularly interested in «memory» T cells, the immune system components that can recognize a foreign substance, such as HIV, that they have seen before and attack when they see it again.

In this last - ditch effort to save these patients, the researchers will extract T cells, immune cells that recognize and kill cells, such as those in bacterial infections, that might be harmful to the body, and tweak their genes so that the cells can now attack cancerous cells.

Because the same individual would donate the precursors of such cells and receive them as therapy, the cells would not spark an immune attack.

In diseases such as Crohn's and ulcerative colitis, the body's immune system attacks parts of the digestive tract.

These drugs work by blocking the effects of histamine, a chemical your body produces to attack invaders like pollen — launching such immune reactions as watery eyes and sneezes.

That strength can backfire, though, leading women to suffer from far more autoimmune disorders — in which the immune system attacks itself — and the host of mysterious diseases thought to sometimes result from an overreactive immune system, such as celiac disease, irritable bowel syndrome (IBS), fibromyalgia, chronic fatigue syndrome (CFS), and many types of pelvic pain.

Thats because some skin and joint diseases, such as psoriasis and rheumatoid arthritis, are caused by the immune system attacking the bodys own tissues.

Normally, your immune system acts as a protector against foreign invaders (such as germs, bacteria and viruses), and its job is to attack these foreign invaders upon sight to keep us healthy.

The immune system can even start to attack itself — the hallmark mechanism of autoimmune diseases such as arthritis and chronic fatigue syndrome.

The effects of such an attack against your own body can cause, for instance, the symptoms of Lupus, an «auto - immune» disease.

This attack by our immune system causes chronic inflammation and may explain many conditions such as atrophic gastritis that destroys both the acid - producing cells and the IF - producing cells in older people who eat meat but do not abuse alcohol.

As if cancer wasn't challenging to begin with, secondary attacks on the immune system from environmental pathogenic influences, such as viruses and bacteria, make the immune system particularly vulnerable in those already experiencing oncological issues.

Studies have established a strong link between digestive health and function and autoimmune diseases such as Hashimoto's hypothyroidism, in which the immune system attacks and destroys the thyroid gland.