Sentences with phrase «such neuroprotective»

Not exact matches

Surreptitiously, a novel neuroprotective strategy for axonal injury, such as traumatic brain injury, has emerged from these studies, which is currently under development.

Indeed, mutations in multiple lysosomal genes result in severe neurodegeneration and it is becoming more clear that lysosomes also play a neuroprotective role in more common neurodegenerative diseases such as Alzheimer's disease that have not traditionally been associated with lysosomal defects.

Background: HDL - cholesterol transporter Apolipoprotein A1 (ApoA1) holds neuroprotective properties, such as inhibition of amyloid - β aggregation.

Abstract: Background: HDL - cholesterol transporter Apolipoprotein A1 (ApoA1) holds neuroprotective properties, such as inhibition of amyloid - β aggregation.

His areas of research include basic mechanisms of retinal cell death in glaucoma, neuroprotective glaucoma therapies, non-invasive imaging of glaucoma damage, and relationships between glaucoma and other chronic neurodegenerations such as Alzheimer's disease.

Foods rich in flavonoids offer a number of neuroprotective properties and can decrease rates of cognitive decline and potentially slow the progression of many neurodegenerative diseases, such as Alzheimer's disease.

2Research has proven these curcuminoids exert powerful health - promoting effects via 160 mechanisms and pathways in the body such as antioxidant, neuroprotective, immunomodulatory, anti-inflammatory, epigenetic, and adaptogenic properties.

When ketone bodies have been used in animals and cell cultures, they have demonstrated neuroprotective qualities such as improving cell survival and cognitive performance (1).

Like in most berry fruits, the neuroprotective and nootropic effects of blackcurrant are related to the combined action of powerful phytochemicals, such as anthocyanin, caffeic acid, catechin, quercetin, kaempferol and tannins.

It has been shown that trans - Resveratrol significantly modulates biomarkers of bone metabolism, inhibits pro-inflammatory enzymes such as COX - 1 and COX - 2, and exhibits chemopreventive agents, anticarcinogenic properties, cardioprotective effects, neuroprotective properties, and caloric restrictive behavior.

Ketone bodies themselves are active signalling metabolites and have demonstrated neuroprotective properties in other brain disorders such as Alzheimer's Disease and Parkinson's Disease (10).

For example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the production of reactive oxygen species in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseases.

Interest in the potential neuroprotective properties of curcumin rose after studies found very low levels of neurological diseases such as Alzheimer's in elderly Indian populations.

They are also important in the synthesis of neuroprotective compounds such as kynurenic acid.