Sentences with phrase «such synaptic changes»

Not exact matches

They used a somewhat bizarre technique in which two mice were sutured together in such as way that they shared a circulatory system (known as parabiosis), and found old mice joined to their youthful counterparts showed changes in gene activity in a brain region called the hippocampus as well as increased neural connections and enhanced «synaptic plasticity» — a mechanism believed to underlie learning and memory in which the strength of neural connections change in response to experience.

Consistent with recent studies of such changes, we find that long - lasting potentiation of synaptic transmission between cultured hippocampal neurons is accompanied by an increase in the number of clusters of postsynaptic glutamate receptors containing the subunit GluR1.

Learning more about how synapses change their connections could help scientists better understand neurodevelopmental disorders such as autism, since many of the genetic alterations linked to autism are found in genes that code for synaptic proteins.

«While our findings are consistent with other reported changes in neuronal firing rates with attention, they go far beyond such descriptions, revealing never - before tested mechanisms at the synaptic level,» said study co-author Farran Briggs, PhD, assistant professor of Physiology and Neurobiology at the Geisel School of Medicine.

It is the changes in the synaptic connections in areas of the brain such as the cerebral cortex and hippocampus that is associated with the learning and retention of new information.

Kauwe and others in Haghighi's lab are exploring why such a change in the set point of synaptic transmission occurs so rapidly, and how dampening neuron activity might be beneficial in treating, or even preventing, neurodegenerative diseases.

Such a «drastic» change was brought about by the development of optical fingerprint sensors, like the Synaptics FS9100, which can be integrated under the glass.