The assessment of headaches depends on identifying the relatively rare instances where serious underlying causes are suspected, says lead author John N. Mafi, MD, a fellow in the Division of General Medicine and Primary Care at BIDMC, who notes that evidence - based guidelines for routine headache, including those from the American Academy of Neurology,
suggest conservative treatments such as counseling on stress reduction or avoiding dietary triggers.
Zoloft (sertraline) and Remeron (mirtazapine), which are both available as generics, also generated more — and more severe — side effects than placebo, leading the researchers to
suggest that these and other antidepressants should be reserved for dementia patients whose depression fails to respond to more
conservative treatments, such as psychotherapy.