Sentences with phrase «suggest potential therapies»
The current study was designed to clarify the cellular hierarchy underlying glioblastoma, to identify epigenetic factors that distinguish glioblastoma stem cells from more differentiated tumor cells and to suggest potential therapies targeting those factors.
https://www.sciencedaily.com/ Not exact matches
As well as reducing inflammation in the lung, MSC therapy also resulted in significant improvements in lung structure, suggesting that this form of treatment has the potential to repair the damaged lung.
Because the researchers found that CTLA4Ig was effective in suppressing hepatitis in this study, they suggest that CTLA4Ig should be among the therapeutic options investigated further as a potential therapy for patients with severe acute hepatitis B. To this end, this animal model is useful for virological and immunological analysis of HBV infection.
Research on metastatic colorectal cancer and sarcoma, however, suggests a potential benefit from adding local therapy — treatment directed specifically at the tumor cells — to the standard approach of systemic therapy.
The researchers suggest that their study demonstrates the potential of these non-toxic therapies to contribute to current cancer treatment regimens and significantly improve the outcome of patients with advanced metastatic cancer.
Importantly this article suggests that geranylgeraniol deserves further study as a potential therapy for human prostate cancer.»
They suggest allocating greater resources to research focused on immune checkpoint therapies and targeted / immunotherapy combination therapies with «curative potential.»
The findings suggest that virtual - reality therapy has the potential to retrain the brain to understand that once painful movements are now safe, extinguishing the association with danger.
Jerry Yee, M.D., division head of Nephrology and Hypertension at Henry Ford and the study's senior author, says the findings suggest the antibiotic therapy is a potential game - changer for hemodialysis treatment.
Two teams of scientists suggest that activating immune cells in fat can convert the tissue from a type of fat that stores energy to one that burns it, opening up potential new therapies for obesity and diabetes.
Studies in patients suggest these systems have potential as therapies and as vaccines
Noting the potential of gene therapy to be a one - time treatment for rare and serious diseases that otherwise cost hundreds of thousands, if not millions, of dollars in chronic care over a lifetime, Stuart Orkin, MD, and co-author Philip Reilly, MD, JD, of Third Rock Ventures, seek to «catalyze the discussion» by suggesting several new models for valuing, pricing and developing gene therapy.
Findings of a three - year clinical trial led by University of Cincinnati (UC) transplant researchers suggest that a novel pre-operative drug therapy reduces antibodies in kidney patients with greater success than with traditional methods, with the potential to increase the patients» candidacy for kidney transplantation and decrease the likelihood of organ rejection.
«We've identified what leads to this difference in vision loss, and that suggests novel potential therapies to treat this serious medical problem in children.
Next Wave asked: If research on gene vectors can be used not only to further gene therapy but also — potentially — to aid in the development of biological weapons, should scientists be concerned about the potential applications of their research in genetics (as Joseph Rotblat suggested in a 19 Nov 1999 editorial in Science magazine?)
Now, in a new study published in the journal Cell, scientists at the Salk Institute for Biological Studies have discovered that a synthetic form of vitamin D, calcipotriol (a drug already approved by the FDA for the treatment of psoriasis), deactivates the switch governing the fibrotic response in mouse liver cells, suggesting a potential new therapy for fibrotic diseases in humans.
Solt notes that the study strongly suggests that Th17 cells have a pathological role in the development of type 1 diabetes and use of ROR - specific synthetic compounds targeting this cell type may have potential as a preventative therapy for type 1 diabetes.
Salk researchers found that a drug already approved by the FDA for the treatment of psoriasis deactivates the switch governing the fibrotic response in mouse liver cells, suggesting a potential new therapy for fibrotic diseases in humans.
Although obtained in rodents, the findings suggest that EA is a potential therapy for hyperalgesia in humans.
«It suggests to us that targeting the pathways used in regulating cell fate decisions — how stem cells choose between cell proliferation and differentiation — could be a more effective way of halting tumours in their tracks and lead to potential new therapies.»
«These studies suggest the potential for dramatically reducing the dose of chemotherapy or radiation and thereby reducing the side effects of standard chemotherapy by enhancing the targeting of cancer therapies using HIV receptor blocking drugs.»
The results contribute to our basic understanding of mitochondria and suggest that EXD2 could be important for fertility and represent a potential target for cancer therapy.
In an editorial published with the study, Viktor Grunwald, of Hannover Medical School, Germany, wrote «these antitumour activity findings indicate the potential clinical benefit of targeted - immune combinations and suggest that further studies are warranted to explore whether a first - line targeted - immune combination might overcome the standard of sequential targeted and immune therapies.»
Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9
Together, our data suggest that clinical studies may be warranted to evaluate the therapeutic potential of ABL allosteric inhibitors and to determine whether combination therapies that incorporate these compounds are effective in treating metastatic breast cancer.
Such trials are inevitably costly, and the traditional strategy for drug development suggests one means of undertaking these development expenses is for wellfunded companies to lead the way, motivated by the potential return on investment to be gained from a successful proprietary therapy.
These new findings suggest additional potential therapeutic opportunities for plasma kallikrein inhibitors in thrombolytic therapy.
These findings suggest that specific MFN2 mutations cause tissue - selective mitochondrial dysfunction with increased adipocyte proliferation and survival, confirm a novel form of excess adiposity with paradoxical suppression of leptin expression, and suggest potential targeted therapies.
«Our findings suggest further investigation into the potential of MC1R - activating agents as novel neuroprotective therapies for PD, and together with epidemiological evidence, may offer information that could guide those carrying MC1R variants to seek advice from dermatologists or neurologists about their personal risk for melanoma and Parkinson's disease,» lead author Xiqun Chen says in a statement.
The past century has unveiled a plethora of preclinical data that has suggested the potential of a ketogenic diet as an aid in cancer treatment.7, 8 The benefits of a ketogenic diet, and dietary manipulation in general, may be a potent adjunct to current cancer treatments by synergistically working with chemotherapy and radiation therapy to starve cancer cells, leaving them more susceptible to damage from these treatments.7 - 10
Dr. Giulio Maria Pasinetti, lead study researcher from the Mount Sinai School of Medicine in New York found the results «strongly suggest that GSPE should be further tested as a potential prevention and / or therapy for AD Alzheimer's Disease.»
The history can provide information about potential exposure to things that may cause skin disease (including fleas), about behaviors that may suggest a cause (like scratching, which suggests itchiness), and about response to therapy.
The challenge results in these three studies strongly suggest a dietary role in the pathogenesis of this disorder and also illustrate the potential importance of dietary therapy.
Dr. Drumheller currently was treating a cat with the Companion Therapy Laser and suggested that just a few treatments may have the potential to improve Dixie's health.
These results show the potential of incorporating positive mood induction within therapeutic programs such as IPT and suggest that IPT could be a worthwhile therapy to use within this patient group.
The American Association of Marriage and Family Therapy (AAMFT) has suggested the following as potential signals of emotional distress which may benefit from professionaltherapy or counseling: