Sentences with phrase «suggested on chromosomes»

The presence of additional modifying variants was suggested on chromosomes 3, 5 and 21; but the associations were not strong enough to be statistically significant.

Not exact matches

CBX2 has aroused interest as a possible master switch for maleness because tests in human cells suggest that mutations in it can shut off a gene on the Y chromosome critical for male sexual development.

Eventually, analysis of DNA from the Pima suggested that they have variations on certain chromosomes that are linked to fatness.

The findings, reported in tomorrow's issue of the Proceedings of the National Academy of Sciences, suggest that disruption of a DNA - tagging system on this chromosome could be responsible for the syndrome.

The study, published last year, found two strong links to homosexuality on different chromosomes, supporting Hamer's findings and suggesting that multiple genes are at work.

«Our data strongly suggest that KIF1Bβ, which is localized on chromosome 1p36, might be such a neuroblastoma tumor suppressor gene,» says principal investigator Susanne Schlisio at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet and Assistant Member at the Ludwig Institute for Cancer Research in Stockholm, Sweden.

Another surprise is that the nematode genes identified so far are packed much more tightly together on the chromosome than anyone had previously expected, which suggests that the nematode has many more genes in total than was previously thought.

Research from other scientists at Johns Hopkins, he says, had suggested that some tumors, particularly those that affect the nervous system, have mutations in the ATRX gene, which produces proteins that appear to maintain the length of telomeres, repetitive segments of DNA on the ends of chromosomes that typically shorten each time a cell divides.

The findings suggest that the information on the X and Y chromosomes that makes this division possible is primed during gametogenesis — the process of creating ovum or sperm cells — in the parents.

Furthermore, the cohanim were much more likely to carry a specific variant of another length of DNA found elsewhere on the Y chromosome than their lay counterparts, suggesting that they share a common ancestor who had this genetic signature.

Several scientists have also suggested that genes on the X chromosome have tended to be conserved in mammalian evolution; similar X-linked genes, that is, can be found in most mammalian species.

The fact that boys are three to four times more likely to be diagnosed with some form of the disorder suggests that at least some genes are carried on the sex chromosomes.

The evidence suggests it does: 249 pairs of siblings were more likely to both have diabetes, or both be healthy, if they shared the same set of genetic markers in the region of the IL - 12 gene on chromosome 5.

A report in the 15 February issue of the Proceedings of the National Academy of Sciences suggests that a lotion containing an algal protein can ward off sunburns — often the first step on the road to skin cancer — by repairing part of the damage to skin cells» chromosomes.

Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome - Wide Search

Traditional genetic methods, such as looking at family trees and sequencing individual genes, have linked defects in 80 genes on the X chromosome to XLMR, but the discovery rate has slowed, suggesting that those techniques have reached their limit.

The researchers also suggest that because the Y can not exchange genes with the X chromosome anymore, it uses other unusual ways to reconfigure its DNA, such as recombining with itself to add on new segments of identical DNA — or palindromes — into its genome.

According to Reeves, the result suggests that genes in the DSCR make their mischief by interacting with other abnormal genes far away on chromosome 21, and that the genetics of Down syndrome are probably more complex than has been generally thought.

Their findings on telomeres, the stretches of DNA at the ends of chromosomes that protect our genetic code and make it possible for cells to divide, suggest a potential target for preventive measures against cancer, aging and other diseases.

Reconstructing relationships using genetic information on the paternally inherited Y chromosome, the maternally inherited mitochondria and the bi-parentally inherited autosomes have suggested contradictory conclusions.

Studies show that the San carry some of the most divergent (oldest) Y - chromosome haplogroups, specific sub-groups of A and B, the two earliest branches on the human Y - chromosome tree, suggesting they may be descendents of a population ancestral to all modern humans.

The gene was mapped to a small region on chromosome 18, which previous studies have suggested may play a role in blood pressure regulation in humans, mice and rats.

The resulting DNA copy number variation and patterns of chromosome loss and gain are tumor - type specific, suggesting differential selective pressures on the two tumor cell types.

355/11: 30 Genetic diversity on the human X chromosome suggests there is no single pseudoautosomal boundary.

While the Anopheline Y had previously been implicated in male mating behavior, recent data from the Anopheles gambiae complex suggests that, apart from the putative primary sex - determiner, no other genes are conserved on the Y. Studying the functional basis of the evolutionary divergence of the Y chromosome in the gambiae complex is complicated by complete F1 male hybrid sterility.

The findings suggest that a gene on the X chromosome may increase a woman's risk of ovarian cancer, independent of other known risk genes, such as the BRCA genes.

New research from a team at Karolinska University suggests that people who stand a lot have longer telomeres - caps on the end of chromosomes which protect DNA from wear and tear.