«After a few minutes you could start to see the formation of iron -
sulfur clusters,» she says.
Less studied is the genesis of iron -
sulfur clusters, the active core in enzymes that drive almost every aspect of cellular chemistry.
A new study suggests that the iron - and -
sulfur clusters at the heart of many life - critical enzymes could have been floating around Earth's primordial seas some 4 billion years ago, produced by nothing more than primitive biomolecules, iron salts, and a previously unknown ingredient — ultraviolet (UV) light.
The Oncogenic Small Tumor Antigen of Merkel Cell Polyomavirus is an Iron -
Sulfur Cluster Protein that Enhances Viral DNA Replication.
In a recent paper in the Journal of Biological Chemistry, Nathan Johnson and colleagues at the University of Wisconsin - Madison write that they found that IRP - 1 activity also could be suppressed by degradation when the iron -
sulfur cluster biogenesis system was disabled, and that there were regulatory feedbacks between the protein degradation and iron -
sulfur cluster mechanisms.
When intracellular iron is high, IRP - 1 is inactivated by the insertion of an iron -
sulfur cluster.
Mutations in genes involved in iron -
sulfur cluster synthesis generally have normal sized red blood cells (normocytic) and may be syndromic or non-syndromic.
Not exact matches
Research shows that
sulfur, which onions are high in, may act as a natural blood thinner and helps prevent blood platelets from
clustering.
The microscopic organism — an archaea known as Metallosphaera sedula (seen as a
cluster of tiny dots sitting in the middle of the meteoritic dust particle pictured above)-- was originally found in 1989 living in Italy's hot acidic
sulfur springs around Vesuvius.
Oxygen is a very reactive molecule that can disrupt the iron - and -
sulfur - containing
clusters of proteins that are crucial to photosynthesis.
Mitochondria provide another cellular service: synthesizing
clusters of iron and
sulfur that are essential helpers for a variety of proteins.
The
clusters consist of cationic polymer binders, battery electrolyte, and anionic
sulfur - active materials.
This illustration shows the formation of complex ion
clusters during the cycling of a lithium -
sulfur battery cell.
The enigmatic SAR202
cluster up close: shedding light on a globally distributed dark ocean lineage involved in
sulfur cycling — Maliheh Mehrshad — The ISME Journal
Also, Peters» work has been vital in defining the first mechanisms for the biosynthesis of the unique iron -
sulfur metal
clusters in certain enzymes.