Sentences with phrase «suppress ctl»

However, findings published on August 14th in PLOS Pathogens now suggest that treatment with HDAC inhibitors might suppress CTL activity and therefore compromise the «kill» part of a two - pronged «flush - and - kill» HIV eradication strategy.

All three drugs also rapidly suppressed CTL production of the key immune mediator interferon gamma.

Not exact matches

The researchers also found that treating the mice with a molecule called CTL - associated antigen - 4 immunoglobulin (CTLA4Ig) suppressed damage to liver cells infected with hepatitis B virus, suggesting that this might be a potential approach to treatment.

Tumors can suppress CD4 + T cell activity and CTL tumor lysis directly through secretion of immunosuppressive factors including TGF - β1 but also PGE - 2, and IL - 10.

Using adoptive transfer experiments we found that spleen cells from persistently infected (carrier) mice actively suppressed the expected LCMV - specific CTL response of spleen cells from normal adult mice.

Such virus variants selectively suppress LCMV - specific CTL responses and cause persistent infections in immunocompetent mice.